Towards germline gene therapy of inherited mitochondrial diseases.
about
Biotechnology. A prudent path forward for genomic engineering and germline gene modificationModulating mitochondrial quality in disease transmission: towards enabling mitochondrial DNA disease carriers to have healthy childrenGenetic manipulation for inherited neurodegenerative diseases: myth or reality?Pairomics, the omics way to mate choiceMitochondrial geneticsArtificial gametes: a systematic review of biological progress towards clinical applicationEvolutionary defined role of the mitochondrial DNA in fertility, disease and ageingMitochondrial transfer: Implications for assisted reproductive technologiesA neurodegenerative perspective on mitochondrial optic neuropathiesCRISPR/Cas9 and mitochondrial gene replacement therapy: promising techniques and ethical considerationsIs there treatment for Leber hereditary optic neuropathy?Mitochondrial DNA disease and developmental implications for reproductive strategiesIs the World of ART Ready for a Ménage à Trois?Nonreductive moral classification and the limits of philosophy.Applying evolutionary biology to address global challenges.The egg. The inside story of a cell.Human embryonic stem cells derived by somatic cell nuclear transfer.Novel methods of treating ovarian infertility in older and POF women, testicular infertility, and other human functional diseases.Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease.Treatment strategies for inherited optic neuropathies: past, present and futureThe costs of being male: are there sex-specific effects of uniparental mitochondrial inheritance?Mitochondrial replacement therapies can circumvent mtDNA-based disease transmissionCloning debate: Stem-cell researchers must stay engaged.A national perspective on prenatal testing for mitochondrial diseaseThree-parent in vitro fertilization: gene replacement for the prevention of inherited mitochondrial diseasesInvestigating human disease using stem cell models.Mitochondrial replacement therapy in reproductive medicine.Selective elimination of mitochondrial mutations in the germline by genome editingStochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism.Implications of human evolution and admixture for mitochondrial replacement therapy.International regulatory landscape and integration of corrective genome editing into in vitro fertilization.Creating a three-parent child: an educational paradigm for the responsible conduct of research.The challenges of mitochondrial replacement.Concise reviews: Assisted reproductive technologies to prevent transmission of mitochondrial DNA diseaseReal-Time PCR Quantification of Heteroplasmy in a Mouse Model with Mitochondrial DNA of C57BL/6 and NZB/BINJ StrainsEliminate mitochondrial diseases by gene editing in germ-line cells and embryos.Maternal control of early embryogenesis in mammalsPreventing the transmission of pathogenic mitochondrial DNA mutations: Can we achieve long-term benefits from germ-line gene transfer?Baby Steps to Superintelligence: Neuroprosthetics and Children.Rendered invisible? The absent presence of egg providers in U.K. debates on the acceptability of research and therapy for mitochondrial disease
P2860
Q22065510-1BDC9860-23B2-4713-B913-F80DBA1B172AQ26741333-E43E06F0-024C-4FE3-8BB7-0ACAA74B4D0FQ26752831-E025BCBE-9A89-4EC2-8482-5CBD6A0FD713Q26809970-6B6E1503-4C29-4798-9CC8-5A610DCAC02FQ26849285-26436D45-5E66-4B43-94A7-806910BEB08FQ27008497-120D05A9-D625-4A98-9A0D-47AD547A474BQ27024089-3661BB77-88E9-4FB2-A2C5-788C993280E3Q28066343-9268104B-70A1-44CB-A9CF-6911DC444224Q28072026-F19EFDAF-2FF9-426C-9637-66FC5CC51EC2Q28073860-A190FBEC-153E-4DD1-822A-49F1B3EDBCC1Q28081486-E85B2A42-7208-476D-B690-126E644D5205Q28649392-B713398A-6828-4220-915B-DDE1C31732BFQ28649733-83429695-FBAA-4229-81D6-FEB568A3B666Q30358900-08A57B0A-F171-4672-9286-501F14D0CA19Q30387318-A2B7FA8F-348C-435F-BACA-E2C20604EF18Q30431119-5B3879CF-3325-4354-8670-2F57198E2AB1Q30544785-C4BA3310-C34A-4963-89A8-A74270291E9DQ30645234-3578292D-C39D-41F6-8920-B0938EE2AF17Q30830400-040558EE-46E6-42C8-BE2D-C6AD01431AB8Q33595163-4773F80D-27E8-45E8-A7A8-F975775BD912Q33655973-0F389F23-9631-4635-8B23-108C1200A9EFQ33893400-D54102CE-6F79-49BC-98C7-58728ECD7CDEQ34350726-3ADFA295-C8B1-456D-A3EB-404A1EB68280Q34356787-13F76883-136B-4610-9D05-02EDD836DB66Q34395166-17444667-0715-4362-8535-A49E2150F214Q34431170-226B8A02-8C11-4F16-A1FF-D4630F6E6133Q34457409-A3EA8405-14AD-45E6-B398-78AAC1075C60Q34473537-3BD52094-5B0A-40EB-8483-17B772FD892DQ34478955-A629DEC9-E078-4E68-9D57-39254E6A238FQ34550835-9BB31D90-1DAF-4AA2-BE82-2858459BF3BCQ34611496-54682E76-3D97-4E1C-930A-F1B28C412E58Q34782004-F4A83149-54BB-4869-B985-2A3E0B304D33Q35156793-3FF4F232-ABB6-4833-9DEB-DA1D303D29FFQ35177384-BAA090A0-116A-4D73-BF6A-89CCE22303BDQ35746098-9B500B0E-CC07-4814-AFB8-F4CABCFDC617Q35816077-EDED62C6-6F53-486C-9AD5-750ECA34ADF6Q35984494-C902F871-5F52-4FD0-BBE5-7A80375FCE06Q36607471-FDB585D2-2575-4704-98CF-CFFF4C8EFD7CQ36678813-90D6D2A1-CB87-4778-B714-4415DA1556E9Q36712666-36633C16-859D-46F4-9682-C7BDC97BDB62
P2860
Towards germline gene therapy of inherited mitochondrial diseases.
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Towards germline gene therapy of inherited mitochondrial diseases.
@ast
Towards germline gene therapy of inherited mitochondrial diseases.
@en
Towards germline gene therapy of inherited mitochondrial diseases.
@nl
type
label
Towards germline gene therapy of inherited mitochondrial diseases.
@ast
Towards germline gene therapy of inherited mitochondrial diseases.
@en
Towards germline gene therapy of inherited mitochondrial diseases.
@nl
prefLabel
Towards germline gene therapy of inherited mitochondrial diseases.
@ast
Towards germline gene therapy of inherited mitochondrial diseases.
@en
Towards germline gene therapy of inherited mitochondrial diseases.
@nl
P2093
P2860
P4510
P356
P1433
P1476
Towards germline gene therapy of inherited mitochondrial diseases.
@en
P2093
Cathy Ramsey
Dario Melguizo Sanchis
David Battaglia
Eunju Kang
Hyo-Sang Lee
Jeffrey Jensen
Joy Woodward
P2860
P2888
P304
P356
10.1038/NATURE11647
P407
P577
2012-10-24T00:00:00Z
P5875
P6179
1041811808