The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
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The telomere syndromesGlobal expression changes resulting from loss of telomeric DNA in fission yeastEvidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence.Axis of ageing: telomeres, p53 and mitochondriaNdj1, a telomere-associated protein, promotes meiotic recombination in budding yeastEvidence that a RecQ helicase slows senescence by resolving recombining telomeresRecruitment of Rad51 and Rad52 to short telomeres triggers a Mec1-mediated hypersensitivity to double-stranded DNA breaks in senescent budding yeastLocalization of telomeres and telomere-associated proteins in telomerase-negative Saccharomyces cerevisiaeThe genome-wide transcription response to telomerase deficiency in the thermotolerant yeast Hansenula polymorpha DL-1.Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence.Long telomeres produced by telomerase-resistant recombination are established from a single source and are subject to extreme sequence scramblingActivation of a LTR-retrotransposon by telomere erosionTelomere maintenance and cancer -- look, no telomerase.Recombination can either help maintain very short telomeres or generate longer telomeres in yeast cells with weak telomerase activity.DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?The telotype defines the telomere state in Saccharomyces cerevisiae and is inherited as a dominant non-Mendelian characteristic in cells lacking telomerase.Identification of novel noncoding transcripts in telomerase-negative yeast using RNA-seq.Hypothesis: Paralog Formation from Progenitor Proteins and Paralog Mutagenesis Spur the Rapid Evolution of Telomere Binding Proteins.The transcriptome of prematurely aging yeast cells is similar to that of telomerase-deficient cells.Saccharomyces cerevisiae as a Model to Study Replicative Senescence Triggered by Telomere Shortening.Telomerase as a useful target in cancer fighting-the breast cancer case.Epigenetic silencing mediates mitochondria stress-induced longevity.Rap1 relocalization contributes to the chromatin-mediated gene expression profile and pace of cell senescenceAging of signal transduction pathways, and pathology.Taming the tiger by the tail: modulation of DNA damage responses by telomeres.Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice.Transcriptional outcome of telomere signalling.Telomere recombination pathways: tales of several unhappy marriages.Mitotic cyclins regulate telomeric recombination in telomerase-deficient yeast cells.Cellular and gene expression responses involved in the rapid growth inhibition of human cancer cells by RNA interference-mediated depletion of telomerase RNA.Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast.Early telomerase inactivation accelerates aging independently of telomere length.Genome-wide transcriptional plasticity underlies cellular adaptation to novel challenge.Est1 protects telomeres and inhibits subtelomeric y'-element recombination.A genomewide suppressor and enhancer analysis of cdc13-1 reveals varied cellular processes influencing telomere capping in Saccharomyces cerevisiae.A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection.Early Loss of Telomerase Action in Yeast Creates a Dependence on the DNA Damage Response Adaptor Proteins.Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction.Cell size regulation during telomere-directed senescence in Saccharomyces cerevisiae.Genotoxicity of chemical compounds identification and assessment by yeast cells transformed with GFP reporter constructs regulated by the PLM2 or DIN7 promoter.
P2860
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P2860
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
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2002 nî lūn-bûn
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2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2002 թվականի հունիսին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
@ast
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
@en
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
@nl
type
label
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
@ast
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
@en
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
@nl
prefLabel
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
@ast
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
@en
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
@nl
P2860
P356
P1476
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
@en
P2093
Joseph L DeRisi
Shivani Nautiyal
P2860
P304
P356
10.1073/PNAS.142162499
P407
P577
2002-06-25T00:00:00Z