Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase
about
Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicasesThe human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activityRoles of Werner syndrome protein in protection of genome integrityHuman premature aging, DNA repair and RecQ helicasesGlobal expression changes resulting from loss of telomeric DNA in fission yeastEvidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence.RecQ helicases in DNA double strand break repair and telomere maintenance.Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatinBreak-induced replication: a review and an example in budding yeastEvidence that a RecQ helicase slows senescence by resolving recombining telomeresPol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation.Length-dependent processing of telomeres in the absence of telomerase.Recruitment of Rad51 and Rad52 to short telomeres triggers a Mec1-mediated hypersensitivity to double-stranded DNA breaks in senescent budding yeastThe Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradationTelomere shortening exposes functions for the mouse Werner and Bloom syndrome genesRecQ helicases: caretakers of the genomeExpression of a RecQ helicase homolog affects progression through crisis in fission yeast lacking telomerase.Localization of telomeres and telomere-associated proteins in telomerase-negative Saccharomyces cerevisiaeNatural and pharmacological regulation of telomeraseSumoylation of the BLM ortholog, Sgs1, promotes telomere-telomere recombination in budding yeast.Distinct roles of RECQ1 in the maintenance of genomic stability.Recombination at long mutant telomeres produces tiny single- and double-stranded telomeric circlesExtrachromosomal telomeric circles contribute to Rad52-, Rad50-, and polymerase delta-mediated telomere-telomere recombination in Saccharomyces cerevisiae.Structural insights into G-quadruplexes: towards new anticancer drugs.A human nuclease specific for G4 DNAAn mre11 mutation that promotes telomere recombination and an efficient bypass of senescence.The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiaeBreak-induced DNA replicationAlternative lengthening of telomeres in mammalian cells.Telomeres: structures in need of unwinding.Involvement of replicative polymerases, Tel1p, Mec1p, Cdc13p, and the Ku complex in telomere-telomere recombination.Junction of RecQ helicase biochemistry and human disease.Characterization of RAD51-independent break-induced replication that acts preferentially with short homologous sequencesG4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition.Long telomeres produced by telomerase-resistant recombination are established from a single source and are subject to extreme sequence scramblingTelomere maintenance without telomerase.Many ways to telomere dysfunction: in vivo studies using mouse models.A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells.A novel family of regulated helicases/nucleases from Gram-positive bacteria: insights into the initiation of DNA recombination.Telomeres, chromosome instability and cancer
P2860
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P2860
Recombination-mediated lengthening of terminal telomeric repeats requires the Sgs1 DNA helicase
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
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2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Recombination-mediated lengthe ...... requires the Sgs1 DNA helicase
@ast
Recombination-mediated lengthe ...... requires the Sgs1 DNA helicase
@en
Recombination-mediated lengthe ...... equires the Sgs1 DNA helicase.
@nl
type
label
Recombination-mediated lengthe ...... requires the Sgs1 DNA helicase
@ast
Recombination-mediated lengthe ...... requires the Sgs1 DNA helicase
@en
Recombination-mediated lengthe ...... equires the Sgs1 DNA helicase.
@nl
prefLabel
Recombination-mediated lengthe ...... requires the Sgs1 DNA helicase
@ast
Recombination-mediated lengthe ...... requires the Sgs1 DNA helicase
@en
Recombination-mediated lengthe ...... equires the Sgs1 DNA helicase.
@nl
P2860
P356
P1476
Recombination-mediated lengthe ...... requires the Sgs1 DNA helicase
@en
P2093
P2860
P304
P356
10.1073/PNAS.061579598
P407
P577
2001-03-13T00:00:00Z