Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis. - Wikidata - wikimedia - TriplyDB

Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis.

Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis.

http://www.wikidata.org/entity/Q34035269

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Impact of soluble epoxide hydrolase and epoxyeicosanoids on human health The role of epoxyeicosatrienoic acids in the cardiovascular system Anti-inflammatory effects of epoxyeicosatrienoic acids Soluble epoxide hydrolase: gene structure, expression and deletion Arg287Gln variant of EPHX2 and epoxyeicosatrienoic acids are associated with insulin sensitivity in humans Attenuation of cisplatin-induced renal injury by inhibition of soluble epoxide hydrolase involves nuclear factor κB signaling Inhibition of soluble epoxide hydrolase attenuates high-fat-diet-induced hepatic steatosis by reduced systemic inflammatory status in mice Soluble epoxide hydrolase deficiency alters pancreatic islet size and improves glucose homeostasis in a model of insulin resistance A dual COX-2/sEH inhibitor improves the metabolic profile and reduces kidney injury in Zucker diabetic fatty rat Epoxyeicosatrienoic acids and glucose homeostasis in mice and men The 2014 Bernard B. Brodie award lecture-epoxide hydrolases: drug metabolism to therapeutics for chronic pain Pharmacological inhibition of soluble epoxide hydrolase ameliorates diet-induced metabolic syndrome in rats Anti-Ulcer Efficacy of Soluble Epoxide Hydrolase Inhibitor TPPU on Diclofenac-Induced Intestinal Ulcers CYP2J2 and Its Metabolites EETs Attenuate Insulin Resistance via Regulating Macrophage Polarization in Adipose Tissue.Mechanism of protection by soluble epoxide hydrolase inhibition in type 2 diabetic stroke Beneficial effects of inhibition of soluble epoxide hydrolase on glucose homeostasis and islet damage in a streptozotocin-induced diabetic mouse model Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids.Epoxyeicosatrienoic acids mediate insulin-mediated augmentation in skeletal muscle perfusion and blood volume Soluble epoxide hydrolase as an anti-inflammatory target of the thrombolytic stroke drug SMTP-7 Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model Eicosanoids, β-cell function, and diabetes Effects of soluble epoxide hydrolase deficiency on acute pancreatitis in mice Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes.Soluble Epoxide Hydrolase Pharmacological Inhibition Ameliorates Experimental Acute Pancreatitis in Mice.Inhibition of soluble epoxide hydrolase in mice promotes reverse cholesterol transport and regression of atherosclerosis Intimal smooth muscle cells are a source but not a sensor of anti-inflammatory CYP450 derived oxylipins.Soluble epoxide hydrolase inhibition improves coronary endothelial function and prevents the development of cardiac alterations in obese insulin-resistant mice.Impact of soluble epoxide hydrolase inhibition on early kidney damage in hyperglycemic overweight mice.Acute augmentation of epoxygenated fatty acid levels rapidly reduces pain-related behavior in a rat model of type I diabetes.The Epoxyeicosatrienoic Acid Pathway Enhances Hepatic Insulin Signaling and is Repressed in Insulin-Resistant Mouse Liver.Pharmacological inhibition of soluble epoxide hydrolase provides cardioprotection in hyperglycemic rats.Soluble epoxide hydrolase deficiency or inhibition attenuates diet-induced endoplasmic reticulum stress in liver and adipose tissue.Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion.Genetic disruption of soluble epoxide hydrolase is protective against streptozotocin-induced diabetic nephropathy CYP450-derived oxylipins mediate inflammatory resolution.Role of soluble epoxide hydrolase in exacerbation of stroke by streptozotocin-induced type 1 diabetes mellitus.A potent soluble epoxide hydrolase inhibitor, t-AUCB, acts through PPARγ to modulate the function of endothelial progenitor cells from patients with acute myocardial infarction Basal and inducible anti-inflammatory epoxygenase activity in endothelial cells.Nitric oxide: orchestrator of endothelium-dependent responses.Reno-protective mechanisms of epoxyeicosatrienoic acids in cardiovascular disease.

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P2860

Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis.

http://www.wikidata.org/entity/Q34035269

description

2010 nî lūn-bûn

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2010 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2010 թվականի մայիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Inhibition or deletion of solu ...... , and reduces islet apoptosis.

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Inhibition or deletion of solu ...... , and reduces islet apoptosis.

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Inhibition or deletion of solu ...... , and reduces islet apoptosis.

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type

label

Inhibition or deletion of solu ...... , and reduces islet apoptosis.

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Inhibition or deletion of solu ...... , and reduces islet apoptosis.

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Inhibition or deletion of solu ...... , and reduces islet apoptosis.

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prefLabel

Inhibition or deletion of solu ...... , and reduces islet apoptosis.

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Inhibition or deletion of solu ...... , and reduces islet apoptosis.

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Inhibition or deletion of solu ...... , and reduces islet apoptosis.

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JPET.110.167544

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Journal of Pharmacology and Experimental Therapeutics

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Inhibition or deletion of solu ...... , and reduces islet apoptosis.

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P2093

Bruce D Hammock

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Christophe Morisseau

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Cong-Yi Wang

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Edward W Inscho

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Hsin-Hsin Chang

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Mong-Heng Wang

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Pengcheng Luo

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Shali Zhang

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Sung Hee Hwang

http://www.w3.org/2001/XMLSchema#string

Yiqiang Zhou

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P2860

Triggering and amplifying pathways of regulation of insulin secretion by glucose.

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas

Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation

Cytochrome P450 epoxygenases, soluble epoxide hydrolase, and the regulation of cardiovascular inflammation

Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function

The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion.

Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension

Dual role of proapoptotic BAD in insulin secretion and beta cell survival

Mechanisms linking obesity to insulin resistance and type 2 diabetes

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430-438

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10.1124/JPET.110.167544

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2

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44570357

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20439437

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