Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists. - Wikidata - wikimedia - TriplyDB

Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists.

Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists.

http://www.wikidata.org/entity/Q34036974

about

Evidence for a single heptahelical domain being turned on upon activation of a dimeric GPCR Different functional roles of T1R subunits in the heteromeric taste receptors Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling Outside-in signaling--a brief review of GPCR signaling with a focus on the Drosophila GPCR family Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior Allosteric modulation of metabotropic glutamate receptors.Metabotropic glutamate receptors: from the workbench to the bedside.High-potency olfactory receptor agonists discovered by virtual high-throughput screening: molecular probes for receptor structure and olfactory function.Structure and ligand recognition of class C GPCRs Mutation-induced quisqualic acid and ibotenic acid affinity at the metabotropic glutamate receptor subtype 4: ligand selectivity results from a synergy of several amino acid residues.Gαo is required for L-canavanine detection in Drosophila.Interdomain movements in metabotropic glutamate receptor activation.Known regulators of nitric oxide synthase and arginase are agonists at the human G-protein-coupled receptor GPRC6A.Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors Estimation of ligand efficacies of metabotropic glutamate receptors from conformational forces obtained from molecular dynamics simulations.How and why do GPCRs dimerize?Molecular basis for amino acid sensing by family C G-protein-coupled receptors.G-protein-coupled receptor oligomers: two or more for what? Lessons from mGlu and GABAB receptors.Metabotropic glutamate receptors: physiology, pharmacology, and disease.Dimers of G-protein coupled receptors as versatile storage and response units Allosteric modulation of metabotropic glutamate receptors: structural insights and therapeutic potential.Human biology of taste.Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1.Organization and functions of mGlu and GABAB receptor complexes.A missense mutation in the seven-transmembrane domain of the human Ca2+ receptor converts a negative allosteric modulator into a positive allosteric modulator.Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.Molecular determinants involved in the allosteric control of agonist affinity in the GABAB receptor by the GABAB2 subunit.Divergent evolution in metabotropic glutamate receptors. A new receptor activated by an endogenous ligand different from glutamate in insects.Molecular similarities in the ligand binding pockets of an odorant receptor and the metabotropic glutamate receptors.Delineating a Ca2+ binding pocket within the venus flytrap module of the human calcium-sensing receptor.

P2860

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P2860

Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists.

http://www.wikidata.org/entity/Q34036974

description

2002 nî lūn-bûn

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2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2002 թվականի հուլիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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name

Closure of the Venus flytrap m ...... ing antagonists into agonists.

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Closure of the Venus flytrap m ...... ing antagonists into agonists.

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Closure of the Venus flytrap m ...... ing antagonists into agonists.

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type

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Closure of the Venus flytrap m ...... ing antagonists into agonists.

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Closure of the Venus flytrap m ...... ing antagonists into agonists.

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Closure of the Venus flytrap m ...... ing antagonists into agonists.

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Closure of the Venus flytrap m ...... ing antagonists into agonists.

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Closure of the Venus flytrap m ...... ing antagonists into agonists.

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Closure of the Venus flytrap m ...... ing antagonists into agonists.

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Proceedings of the National Academy of Sciences of the United States of America

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Closure of the Venus flytrap m ...... ing antagonists into agonists.

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P2093

Anne-Sophie Bessis

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Florence Gaven

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Francine Acher

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Isabelle Brabet

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Jean-Philippe Pin

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Laurent Prezeau

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Nicolas Triballeau

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Philippe Rondard

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Heterodimerization is required for the formation of a functional GABA(B) receptor

Molecular tinkering of G protein-coupled receptors: an evolutionary success

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Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone

Structural views of the ligand-binding cores of a metabotropic glutamate receptor complexed with an antagonist and both glutamate and Gd3+.

Crystal structure of AmiC: the controller of transcription antitermination in the amidase operon of Pseudomonas aeruginosa

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10.1073/PNAS.162138699

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17

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12151600

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