The molecular balancing act of p16(INK4a) in cancer and aging.
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Biomarkers of Aging: From Function to Molecular BiologyThe rs11515 Polymorphism Is More Frequent and Associated With Aggressive Breast Tumors with Increased ANRIL and Decreased p16 (INK4a) ExpressionDownregulation of P16 promotes cigarette smoke extract-induced vascular smooth muscle cell proliferation via preventing G1/S phase transitionThe role of senescent cells in ageing.The history and future of targeting cyclin-dependent kinases in cancer therapy.mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation.Relationships among folate, alcohol consumption, gene variants in one-carbon metabolism and p16INK4a methylation and expression in healthy breast tissues.The overexpression of p16 is not a surrogate marker for high-risk human papilloma virus genotypes and predicts clinical outcomes for vulvar cancer.A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity.A Tox21 Approach to Altered Epigenetic Landscapes: Assessing Epigenetic Toxicity Pathways Leading to Altered Gene Expression and Oncogenic Transformation In VitroAcute myeloid leukemia requires Hhex to enable PRC2-mediated epigenetic repression of Cdkn2aMetabolic Reprogramming of Pancreatic Cancer Mediated by CDK4/6 Inhibition Elicits Unique VulnerabilitiesmiR-494-3p Induces Cellular Senescence and Enhances Radiosensitivity in Human Oral Squamous Carcinoma Cells.Amyloid β Protein Aggravates Neuronal Senescence and Cognitive Deficits in 5XFAD Mouse Model of Alzheimer's Disease.Polyunsaturated fatty acids ameliorate aging via redox-telomere-antioncogene axis.Clinicopathological and immunohistological features of polypoid endometriosis.Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with the variant RNF213-, ATIC- and TPM3-ALK fusions is characterized by copy number gain of the rearranged ALK gene.Melanocytic nevi and melanoma: unraveling a complex relationship.AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms.Aging: Treating the Older Patient.Management of Cancer in the Older Age Person: An Approach to Complex Medical Decisions.Copy number profiling of tumor suppressor genes in head and neck cancer.The Role of p16INK4a Pathway in Human Epidermal Stem Cell Self-Renewal, Aging and CancerEBV-Positive and EBV-Negative Posttransplant Diffuse Large B Cell Lymphomas Have Distinct Genomic and Transcriptomic Features.Increased p16 and p53 protein expression predicts poor prognosis in mucosal melanoma.Effect of Iodine Intake on p14ARF and p16INK4a Expression in Thyroid Papillary Carcinoma in Rats.The Biology of Aging and Cancer: A Brief Overview of Shared and Divergent Molecular Hallmarks.In vitro effects of Apixaban on 5 different cancer cell lines.Differential impact of RB status on E2F1 reprogramming in human cancer.Mitochondrial BMI1 maintains bioenergetic homeostasis in cells.Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia.Recent advances of cyclin-dependent kinases as potential therapeutic targets in HR+/HER2- metastatic breast cancer: a focus on ribociclib.TFIIA transcriptional activity is controlled by a 'cleave-and-run' Exportin-1/Taspase 1-switch.Cellular senescence and aging.Differential expression of cyclin D1, Ki‑67, pRb, and p53 in psoriatic skin lesions and normal skin.Cell Cycle Regulation in Treatment of Breast Cancer.Obesity and p16INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity.p16INK4A induces senescence and inhibits EMT through microRNA-141/microRNA-146b-5p-dependent repression of AUF1.Expression profiles analysis identifies a novel three-mRNA signature to predict overall survival in oral squamous cell carcinoma.High-fat diet modifies expression of hepatic cellular senescence gene p16(INK4a) through chromatin modifications in adult male rats.
P2860
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P2860
The molecular balancing act of p16(INK4a) in cancer and aging.
description
2013 nî lūn-bûn
@nan
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The molecular balancing act of p16
@nl
The molecular balancing act of p16(INK4a) in cancer and aging.
@ast
The molecular balancing act of p16(INK4a) in cancer and aging.
@en
type
label
The molecular balancing act of p16
@nl
The molecular balancing act of p16(INK4a) in cancer and aging.
@ast
The molecular balancing act of p16(INK4a) in cancer and aging.
@en
prefLabel
The molecular balancing act of p16
@nl
The molecular balancing act of p16(INK4a) in cancer and aging.
@ast
The molecular balancing act of p16(INK4a) in cancer and aging.
@en
P2860
P1476
The molecular balancing act of p16(INK4a) in cancer and aging.
@en
P2093
Christin E Burd
Kyle M LaPak
P2860
P304
P356
10.1158/1541-7786.MCR-13-0350
P577
2013-10-17T00:00:00Z