about
CC-1065 and the duocarmycins: unraveling the keys to a new class of naturally derived DNA alkylating agentsCleavage behavior of calicheamicin gamma 1 and calicheamicin TMechanistic studies on DNA damage by minor groove binding copper-phenanthroline conjugates.Small molecule chemical probes of microRNA functionCrystal structure of a berenil-dodecanucleotide complex: the role of water in sequence-specific ligand bindingVariability in DNA minor groove width recognised by ligand binding: the crystal structure of a bis-benzimidazole compound bound to the DNA duplex d(CGCGAATTCGCG)2Sequence-dependent effects in drug-DNA interaction: the crystal structure of Hoechst 33258 bound to the d(CGCAAATTTGCG)2 duplexDesigner DNA-binding drugs: the crystal structure of a meta-hydroxy analogue of Hoechst 33258 bound to d(CGCGAATTCGCG)2Structure of a bis-amidinium derivative of hoechst 33258 complexed to dodecanucleotide d(CGCGAATTCGCG)2: the role of hydrogen bonding in minor groove drug-DNA recognitionRecognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligandsFoldamers as versatile frameworks for the design and evolution of functionPolyamide-scorpion cyclam lexitropsins selectively bind AT-rich DNA independently of the nature of the coordinated metalNew Chemical and Stereochemical Applications of Organoiron ComplexesSite-specific cleavage of RNA by Fe(II).bleomycin.Dissociation of minor groove binders from DNA: insights from metadynamics simulations.Interaction between antitumor drugs and a double-stranded oligonucleotide studied by electrospray ionization mass spectrometry.FTIR study of specific binding interactions between DNA minor groove binding ligands and polynucleotides.The Hoechst 33258 covalent dimer covers a total turn of the double-stranded DNA.Tris(tetramethylphenanthroline)ruthenium(II): a chiral probe that cleaves A-DNA conformations.De novo design of antimicrobial polymers, foldamers, and small molecules: from discovery to practical applications.Reactivity of Nucleic Acid Radicals.Bidirectional binding of the TATA box binding protein to the TATA boxEvidence for DNA phosphate backbone alkylation and cleavage by pyrrolo[1,2-a]benzimidazoles: small molecules capable of causing base-pair-specific phosphodiester bond hydrolysis.Esperamicins, a class of potent antitumor antibiotics: mechanism of action.Model of the interactions of calichemicin gamma 1 with a DNA fragment from pBR322.Binding of actinomycin D to DNA: evidence for a nonclassical high-affinity binding mode that does not require GpC sites.Neomycin-neomycin dimer: an all-carbohydrate scaffold with high affinity for AT-rich DNA duplexes.Factors influencing the DNA nuclease activity of iron, cobalt, nickel, and copper chelates.The td intron endonuclease I-TevI makes extensive sequence-tolerant contacts across the minor groove of its DNA targetReal-time imaging of single DNA molecules with fluorescence microscopy.Drug Self-Assembly on DNA: Sequence Effects with trans-bis-(4-N-methylpyridiniumyl)diphenyl Porphyrin and Hoechst 33258.Design, synthesis and biological evaluation of a novel class of anticancer agents: anthracenylisoxazole lexitropsin conjugatesGuiding the design of synthetic DNA-binding molecules with massively parallel sequencing.Mithramycin blocks protein binding and function of the SV40 early promoter.An NMR study of [d(CGCGAATTCGCG)]2 containing an interstrand cross-link derived from a distamycin-pyrrole conjugateHoogsteen base pairs proximal and distal to echinomycin binding sites on DNAOrigins of netropsin binding affinity and specificity: correlations of thermodynamic and structural dataThe binding modes of a rationally designed photoactivated DNA nuclease determined by NMR.Sequence specific inhibition of DNA restriction enzyme cleavage by PNA.Double-stranded cleavage of pBR322 by a diiron complex via a "hydrolytic" mechanism
P2860
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P2860
description
1986 nî lūn-bûn
@nan
1986 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
Design of sequence-specific DNA-binding molecules.
@ast
Design of sequence-specific DNA-binding molecules.
@en
Design of sequence-specific DNA-binding molecules.
@nl
type
label
Design of sequence-specific DNA-binding molecules.
@ast
Design of sequence-specific DNA-binding molecules.
@en
Design of sequence-specific DNA-binding molecules.
@nl
prefLabel
Design of sequence-specific DNA-binding molecules.
@ast
Design of sequence-specific DNA-binding molecules.
@en
Design of sequence-specific DNA-binding molecules.
@nl
P356
P1433
P1476
Design of sequence-specific DNA-binding molecules.
@en
P2093
P304
P356
10.1126/SCIENCE.2421408
P407
P577
1986-04-01T00:00:00Z