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SRC: a century of science brought to the clinic.

SRC: a century of science brought to the clinic.

http://www.wikidata.org/entity/Q34041298

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ErbB2, EphrinB1, Src kinase and PTPN13 signaling complex regulates MAP kinase signaling in human cancers Dinosaurs and ancient civilizations: reflections on the treatment of cancer AMPK as a potential anticancer target - friend or foe?Emerging therapeutic strategies for Epstein-Barr virus+ post-transplant lymphoproliferative disorder Lipid raft: A floating island of death or survival CCR5 receptor antagonists block metastasis to bone of v-Src oncogene-transformed metastatic prostate cancer cell lines.Novel autophosphorylation sites of Src family kinases regulate kinase activity and SH2 domain-binding capacity Regulation of SRC family kinases in human cancers AFAP1 Is a Novel Downstream Mediator of TGF-β1 for CCN2 Induction in Osteoblasts The blood-testis barrier and its implications for male contraception In silico investigation of potential SRC kinase ligands from traditional Chinese medicine ASPP2 suppresses stem cell-like characteristics and chemoresistance by inhibiting the Src/FAK/Snail axis in hepatocellular carcinoma.The regulation of N-methyl-D-aspartate receptors by Src kinase.Interaction of Src and Alpha-V Integrin Regulates Fibroblast Migration and Modulates Lung Fibrosis in A Preclinical Model of Lung Fibrosis Carcinoma matrix controls resistance to cisplatin through talin regulation of NF-kB C-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics.Posttranscriptional deregulation of Src due to aberrant miR34a and miR203 contributes to gastric cancer development Combined BRAF(V600E)- and SRC-inhibition induces apoptosis, evokes an immune response and reduces tumor growth in an immunocompetent orthotopic mouse model of anaplastic thyroid cancer.Emerging therapies in metastatic bone pain.Therapeutic targeting of SRC kinase in myofibroblast differentiation and pulmonary fibrosis.ADAM15 adds to apoptosis resistance of synovial fibroblasts by modulating focal adhesion kinase signaling.Elucidation of the roles of the Src kinases in pancreatic acinar cell signaling Src-mediated phosphorylation of the tyrosine phosphatase PRL-3 is required for PRL-3 promotion of Rho activation, motility and invasion VEGFR2 and Src kinase inhibitors suppress Andes virus-induced endothelial cell permeability Transcriptome Analysis Reveals Novel Entry Mechanisms and a Central Role of SRC in Host Defense during High Multiplicity Mycobacterial Infection Differential transformation capacity of Src family kinases during the initiation of prostate cancer.Targeting tumor cell motility to prevent metastasis.Src family kinases and paclitaxel sensitivity.A critical role of Src family kinase in SDF-1/CXCR4-mediated bone-marrow progenitor cell recruitment to the ischemic heart.The interconnectedness of cancer cell signaling.SRC family kinase inhibitors antagonize the toxicity of multiple serotypes of botulinum neurotoxin in human embryonic stem cell-derived motor neurons Activation pathway of Src kinase reveals intermediate states as targets for drug design LRIG1 modulates cancer cell sensitivity to Smac mimetics by regulating TNFα expression and receptor tyrosine kinase signaling Phosphatidylinositol Phosphate 5-Kinase Iγ and Phosphoinositide 3-Kinase/Akt Signaling Couple to Promote Oncogenic Growth.EGFR inhibition evokes innate drug resistance in lung cancer cells by preventing Akt activity and thus inactivating Ets-1 function Shear stress induces cell apoptosis via a c-Src-phospholipase D-mTOR signaling pathway in cultured podocytes.Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line.Heat dissipation guides activation in signaling proteins Src/STAT3-dependent heme oxygenase-1 induction mediates chemoresistance of breast cancer cells to doxorubicin by promoting autophagy.Src-signaling interference impairs the dissemination of blood-borne tumor cells

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SRC: a century of science brought to the clinic.

http://www.wikidata.org/entity/Q34041298

description

2010 nî lūn-bûn

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2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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SRC: a century of science brought to the clinic.

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SRC: a century of science brought to the clinic.

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SRC: a century of science brought to the clinic.

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SRC: a century of science brought to the clinic.

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SRC: a century of science brought to the clinic.

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SRC: a century of science brought to the clinic.

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SRC: a century of science brought to the clinic.

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SRC: a century of science brought to the clinic.

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Alexey Aleshin

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Richard S Finn

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The Hallmarks of Cancer

Identification of protein-tyrosine phosphatase 1B as the major tyrosine phosphatase activity capable of dephosphorylating and activating c-Src in several human breast cancer cell lines

Integrin-regulated FAK-Src signaling in normal and cancer cells

Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases

A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent manner

SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells.

Tyrosine kinase signalling in breast cancer: epidermal growth factor receptor and c-Src interactions in breast cancer.

The hunting of the Src

Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias

PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells

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599-607

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scholarly article

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10.1593/NEO.10328

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8

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12

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2010-08-01T00:00:00Z

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45509134

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20689754

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2915404

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