MDM2 regulates hypoxic hypoxia-inducible factor 1α stability in an E3 ligase, proteasome, and PTEN-phosphatidylinositol 3-kinase-AKT-dependent manner.
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DUBs, New Members in the Hypoxia Signaling clUbCurrent relevance of hypoxia in head and neck cancerAnti-tumor effect of a novel PI3-kinase inhibitor, SF1126, in (12) V-Ha-Ras transgenic mouse glioma model.TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation.DEC2 expression is positively correlated with HIF-1 activation and the invasiveness of human osteosarcomas.Hispidulin prevents hypoxia-induced epithelial-mesenchymal transition in human colon carcinoma cells.Hypoxia-inducible factors in cancer stem cells and inflammation.Folic Acid Represses Hypoxia-Induced Inflammation in THP-1 Cells through Inhibition of the PI3K/Akt/HIF-1α PathwayPerturbations of PIP3 signalling trigger a global remodelling of mRNA landscape and reveal a transcriptional feedback loop.Hypoxia induces H19 expression through direct and indirect Hif-1α activity, promoting oncogenic effects in glioblastomaThe clinical and therapeutic uses of MDM2 and PSMA and their potential interaction in aggressive cancers.Single Agent and Synergistic Activity of the "First-in-Class" Dual PI3K/BRD4 Inhibitor SF1126 with Sorafenib in Hepatocellular Carcinoma.FAT1 is a novel upstream regulator of HIF1α and invasion of high grade glioma.Pan-PI-3 kinase inhibitor SF1126 shows antitumor and antiangiogenic activity in renal cell carcinoma.GATA3 interacts with and stabilizes HIF-1α to enhance cancer cell invasiveness.Hypoxia-Induced Signaling Promotes Prostate Cancer Progression: Exosomes Role as Messenger of Hypoxic Response in Tumor MicroenvironmentOverexpression of hypoxia-inducible factor and metabolic pathways: possible targets of cancer.Non-Canonical Mechanisms Regulating Hypoxia-Inducible Factor 1 Alpha in Cancer.Tyrosines-740/751 of PDGFRβ contribute to the activation of Akt/Hif1α/TGFβ nexus to drive high glucose-induced glomerular mesangial cell hypertrophy.The expression pattern of Bcl11a, Mdm2 and Pten genes in B-cell acute lymphoblastic leukemia.BP-1T, an antiangiogenic benzophenone-thiazole pharmacophore, counteracts HIF-1 signalling through p53/MDM2-mediated HIF-1α proteasomal degradation.
P2860
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P2860
MDM2 regulates hypoxic hypoxia-inducible factor 1α stability in an E3 ligase, proteasome, and PTEN-phosphatidylinositol 3-kinase-AKT-dependent manner.
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
MDM2 regulates hypoxic hypoxia ...... 3-kinase-AKT-dependent manner.
@ast
MDM2 regulates hypoxic hypoxia ...... 3-kinase-AKT-dependent manner.
@en
MDM2 regulates hypoxic hypoxia ...... 3-kinase-AKT-dependent manner.
@nl
type
label
MDM2 regulates hypoxic hypoxia ...... 3-kinase-AKT-dependent manner.
@ast
MDM2 regulates hypoxic hypoxia ...... 3-kinase-AKT-dependent manner.
@en
MDM2 regulates hypoxic hypoxia ...... 3-kinase-AKT-dependent manner.
@nl
prefLabel
MDM2 regulates hypoxic hypoxia ...... 3-kinase-AKT-dependent manner.
@ast
MDM2 regulates hypoxic hypoxia ...... 3-kinase-AKT-dependent manner.
@en
MDM2 regulates hypoxic hypoxia ...... 3-kinase-AKT-dependent manner.
@nl
P2093
P2860
P356
P1476
MDM2 regulates hypoxic hypoxia ...... 3-kinase-AKT-dependent manner.
@en
P2093
Alok R Singh
Donald L Durden
Shweta Joshi
P2860
P304
22785-22797
P356
10.1074/JBC.M114.587493
P407
P577
2014-06-30T00:00:00Z