about
Double strand binding-single strand incision mechanism for human flap endonuclease: implications for the superfamilyComplexes of HIV-1 RT, NNRTI and RNA/DNA hybrid reveal a structure compatible with RNA degradationThe orientation of the C-terminal domain of the Saccharomyces cerevisiae Rap1 protein is determined by its binding to DNAStructural Characterization of Viral Ortholog of Human DNA Glycosylase NEIL1 Bound to Thymine Glycol or 5-Hydroxyuracil-containing DNAStructural Insights into the Role of Domain Flexibility in Human DNA Ligase IVNMR structure of an ethylene interstrand cross-linked DNA which mimics the lesion formed by 1,3-bis(2-chloroethyl)-1-nitrosoureaPathophysiology of bronchoconstriction: role of oxidatively damaged DNA repairDeveloping advanced X-ray scattering methods combined with crystallography and computationSoftware for the high-throughput collection of SAXS data using an enhanced Blu-Ice/DCS control system.Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a timeXPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase.XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaksXLF regulates filament architecture of the XRCC4·ligase IV complex.Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypesAn S/T-Q cluster domain census unveils new putative targets under Tel1/Mec1 control.A new structural framework for integrating replication protein A into DNA processing machinery.A structural model for regulation of NHEJ by DNA-PKcs autophosphorylationCharacterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod-Debye law.Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNAAll stressed out without ATM kinaseValidation of macromolecular flexibility in solution by small-angle X-ray scattering (SAXS).Accurate SAXS profile computation and its assessment by contrast variation experimentsThe disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactionsRepair of double-strand breaks by end joining.Three-pronged probes: high-affinity DNA binding with cap, β-alanines and oligopyrrolamides.What Combined Measurements From Structures and Imaging Tell Us About DNA Damage Responses.Structural biology of DNA repair: spatial organisation of the multicomponent complexes of nonhomologous end joining.Detection of parametric changes in the Peyrard-Bishop- Dauxois model of DNA using nonlinear Kalman filtering.The fidelity of the ligation step determines how ends are resolved during nonhomologous end joining.Spatial and temporal organization of multi-protein assemblies: achieving sensitive control in information-rich cell-regulatory systems.
P2860
Q26850039-D7812EF5-BD8E-4A0C-8360-6D810B9808C1Q27675888-552E3EE2-B65E-4B75-9F76-80F2FA3E5CB7Q27675973-A82863C9-A276-45B4-96E2-8D1A16FE6856Q27676196-1C49514F-7AA6-4618-BA17-AEC8BB33CCE2Q27679426-9D6D7294-A6B0-4292-8A54-30E1BE9C588FQ27690740-93BA3E27-0A7E-4E9B-BF2C-A34CAA7248B3Q28088316-93583B68-8582-4F43-BA66-D6A505C45A21Q28681355-980AA7DD-6E91-45F5-A8D5-01E29B5DEA57Q33727781-750D9923-4529-4238-81C5-B302FBFE960CQ33914715-BF159CB5-8DA0-415C-B7B2-C02E6FB8447FQ34184951-8BB5347A-581B-40C8-885C-99AC93B15407Q34329896-5C3D7B0B-89C5-4D64-A6E6-7B5DF217A1CFQ34432615-FEB53482-5791-4564-9C7C-467F602E5312Q34433470-FB54F21D-BEBD-4D6E-861F-CE8E7B5FECA2Q34442177-8959B86A-8E24-40F3-A7F1-3C8F8741F69FQ34487215-2B64DB37-DF0B-4D12-BDAE-E7E23141F6B2Q34543373-592C1F66-B22A-42CC-8745-F5E6710C2127Q34610477-05F190B6-7932-48C3-A1BD-EC42C6B7ED0BQ35012139-C6F8CFBF-EE17-4CCB-87CE-EF98B8D7CCFFQ35224383-10E065AC-B488-4BD2-86FA-432A716ED7A8Q35841601-6B031B3A-B794-466F-8BA1-0C393AEDB8D7Q36293440-D67766A9-BEBB-49B9-AB15-A7DD9AFAAA18Q37117438-5E47B027-BDD9-4DB9-A0DA-5E91D5CD4BE7Q37187941-7D01B01D-E0DD-4744-BBAB-EACF8260F7D5Q38103528-A1AD1007-1AD5-459A-92CE-A017C267CB46Q38311246-E4BFED24-609F-4F95-BBA9-6403C910BA72Q41319392-A76D891F-DAA4-4AE3-AD91-C92CD868AFBAQ41772188-84E760BE-9092-4D43-871E-36F49EF09AABQ42554033-3B49EF57-1B4C-490F-AC85-0A1DE3782B6CQ42744119-70E79399-C29E-49B0-89F9-921572EEB7D0Q48526269-73854A0A-4FB8-46E1-9B68-9DCB32027ABD
P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structural dynamics in DNA damage signaling and repair
@ast
Structural dynamics in DNA damage signaling and repair
@en
Structural dynamics in DNA damage signaling and repair
@nl
type
label
Structural dynamics in DNA damage signaling and repair
@ast
Structural dynamics in DNA damage signaling and repair
@en
Structural dynamics in DNA damage signaling and repair
@nl
prefLabel
Structural dynamics in DNA damage signaling and repair
@ast
Structural dynamics in DNA damage signaling and repair
@en
Structural dynamics in DNA damage signaling and repair
@nl
P2093
P2860
P1476
Structural dynamics in DNA damage signaling and repair
@en
P2093
Elizabeth Cotner-Gohara
J Jefferson P Perry
John A Tainer
Tom Ellenberger
P2860
P304
P356
10.1016/J.SBI.2010.03.012
P577
2010-05-01T00:00:00Z