Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis. - Wikidata - wikimedia - TriplyDB

Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis.

Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis.

http://www.wikidata.org/entity/Q34048178

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Insights on Molecular Mechanisms of Chondrocytes Death in Osteoarthritis When NRF2 talks, who's listening?Cytoprotection "gone astray": Nrf2 and its role in cancer The clinical potential of influencing Nrf2 signaling in degenerative and immunological disorders alpha4 beta1-Integrin regulates directionally persistent cell migration in response to shear flow stimulation.Microfluidics as a functional tool for cell mechanics Prolonged application of high fluid shear to chondrocytes recapitulates gene expression profiles associated with osteoarthritis.Loss of giant obscurins promotes breast epithelial cell survival through apoptotic resistance Shear stress modulates macrophage-induced urokinase plasminogen activator expression in human chondrocytes.Prostaglandin (PG)D(2) and 15-deoxy-Delta(12,14)-PGJ(2), but not PGE(2), mediate shear-induced chondrocyte apoptosis via protein kinase A-dependent regulation of polo-like kinases Prostaglandin E2 induces interleukin-6 expression in human chondrocytes via cAMP/protein kinase A- and phosphatidylinositol 3-kinase-dependent NF-kappaB activation.NSAIDs inhibit neovascularization of choroid through HO-1-dependent pathway.Elastomeric microposts integrated into microfluidics for flow-mediated endothelial mechanotransduction analysis.Shear-induced interleukin-6 synthesis in chondrocytes: roles of E prostanoid (EP) 2 and EP3 in cAMP/protein kinase A- and PI3-K/Akt-dependent NF-kappaB activation.Interleukin-6 synthesis in human chondrocytes is regulated via the antagonistic actions of prostaglandin (PG)E2 and 15-deoxy-Δ(12,14)-PGJ2.Targeting nrf2 signaling to combat chemoresistance.Thermomodulated cell culture∕harvest in polydimethylsiloxane microchannels with poly(N-isopropylacrylamide)-grafted surface.Oxidative stress in secondary osteoarthritis: from cartilage destruction to clinical presentation?Response of chondrocytes to shear stress: antagonistic effects of the binding partners Toll-like receptor 4 and caveolin-1.Biomechanical influence of cartilage homeostasis in health and disease A perspective on microarrays: current applications, pitfalls, and potential uses Fluid shear promotes chondrosarcoma cell invasion by activating matrix metalloproteinase 12 via IGF-2 and VEGF signaling pathways.By activating matrix metalloproteinase-7, shear stress promotes chondrosarcoma cell motility, invasion and lung colonization.Lubricin restoration in a mouse model of congenital deficiency.The antagonistic actions of endogenous interleukin-1β and 15-deoxy-Δ12,14-prostaglandin J2 regulate the temporal synthesis of matrix metalloproteinase-9 in sheared chondrocytes.Antioxidants block cyclic loading induced chondrocyte death Viability analysis and apoptosis induction of breast cancer cells in a microfluidic device: effect of cytostatic drugs.Cells of the synovium in rheumatoid arthritis. Chondrocytes.Notch4-dependent antagonism of canonical TGF-β1 signaling defines unique temporal fluctuations of SMAD3 activity in sheared proximal tubular epithelial cells.Regulation of chondrocytic gene expression by biomechanical signals.Age-related carbonylation of fibrocartilage structural proteins drives tissue degenerative modification.Cartilage homeostasis in health and rheumatic diseases.Rifampicin Attenuated Global Cerebral Ischemia Injury via Activating the Nuclear Factor Erythroid 2-Related Factor Pathway.Over-expression of Toll-like receptor 2 up-regulates heme oxygenase-1 expression and decreases oxidative injury in dairy goats.The cytoprotective role of the Keap1-Nrf2 pathway.Physiology and pathophysiology of nitrosative and oxidative stress in osteoarthritic joint destruction.The potential for dietary factors to prevent or treat osteoarthritis.Chondropenia: current concept review.The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction.EGFR-activated signaling and actin remodeling regulate cyclic stretch-induced NRF2-ARE activation.

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Divergent responses of chondrocytes and endothelial cells to shear stress: cross-talk among COX-2, the phase 2 response, and apoptosis.

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2005 nî lūn-bûn

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2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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Divergent responses of chondro ...... ase 2 response, and apoptosis.

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Divergent responses of chondro ...... ase 2 response, and apoptosis.

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Divergent responses of chondro ...... ase 2 response, and apoptosis.

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Divergent responses of chondro ...... ase 2 response, and apoptosis.

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Divergent responses of chondro ...... ase 2 response, and apoptosis.

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Divergent responses of chondro ...... ase 2 response, and apoptosis.

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Divergent responses of chondro ...... ase 2 response, and apoptosis.

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Divergent responses of chondro ...... ase 2 response, and apoptosis.

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Divergent responses of chondro ...... ase 2 response, and apoptosis.

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Divergent responses of chondro ...... ase 2 response, and apoptosis.

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Konstantinos Konstantopoulos

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Mary B Goldring

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Norman H Lee

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Paul Talalay

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Thomas W Kensler

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Xiangqun Gao

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Zachary R Healy

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P2860

CITED2-mediated regulation of MMP-1 and MMP-13 in human chondrocytes under flow shear

Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors.

Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress

Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins

Differential responses of the Nrf2-Keap1 system to laminar and oscillatory shear stresses in endothelial cells

Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes

Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers

The glutathione defense system in the pathogenesis of rheumatoid arthritis.

Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: the indirect antioxidant effects of sulforaphane.

A concise guide to cDNA microarray analysis.

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