Design of potent inhibitors of human RAD51 recombinase based on BRC motifs of BRCA2 protein: modeling and experimental validation of a chimera peptide.
about
Valine 1532 of human BRC repeat 4 plays an important role in the interaction between BRCA2 and RAD51Surfing the Protein-Protein Interaction Surface Using Docking Methods: Application to the Design of PPI InhibitorsChemotherapeutic compounds targeting the DNA double-strand break repair pathways: the good, the bad, and the promisingInterrogation of the protein-protein interactions between human BRCA2 BRC repeats and RAD51 reveals atomistic determinants of affinityContributions of the RAD51 N-terminal domain to BRCA2-RAD51 interaction.Applications of isothermal titration calorimetry in pure and applied research--survey of the literature from 2010.RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cellsAn optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity.Quantitative Affinity Determination by Fluorescence Anisotropy Measurements of Individual Nanoliter Droplets.A phosphorylation-deubiquitination cascade regulates the BRCA2-RAD51 axis in homologous recombination.Targeting homologous recombination-mediated DNA repair in cancer.High levels of BRC4 induced by a Tet-On 3G system suppress DNA repair and impair cell proliferation in vertebrate cells.Computational prediction and analysis of the DR6-NAPP interaction.Structure-activity relationship of the peptide binding-motif mediating the BRCA2:RAD51 protein-protein interaction.
P2860
Q24304116-BE2D3CF8-1683-4EA8-A722-0C7D0FEC29D8Q26823990-CF9DA23E-68AF-44EC-BB6D-F9BE37D98878Q26863501-21390809-3AF3-41ED-B8F1-EA883528C842Q28479016-DEAE631C-CCF4-4B83-A088-411548BBAFCCQ30551528-FD69B08B-4FC4-4412-A2AF-781FB6D5B486Q34244067-ABA23FCA-3508-4744-9128-7C1CAEB6D096Q34273832-8437FEB6-9322-45EC-BE9E-F182D70651A8Q34316998-95FD4E37-EC6F-4A4B-BCF3-E590D354ACC9Q36278893-79DAE4A1-0CDD-4D39-A028-AC4A83DD0395Q37548532-7E39F3E1-5FC9-4155-9184-8CEE269359E0Q38184667-EF6EC465-584E-4603-B202-36716D97D727Q38956850-250A2651-5E87-4125-95B1-5AB889D9D47EQ39780607-81522DC4-DF3D-4780-88D0-A7B8C07ACED1Q42837372-BCE46E10-2C97-451D-B405-C526441E806B
P2860
Design of potent inhibitors of human RAD51 recombinase based on BRC motifs of BRCA2 protein: modeling and experimental validation of a chimera peptide.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Design of potent inhibitors of ...... lidation of a chimera peptide.
@ast
Design of potent inhibitors of ...... lidation of a chimera peptide.
@en
Design of potent inhibitors of ...... lidation of a chimera peptide.
@nl
type
label
Design of potent inhibitors of ...... lidation of a chimera peptide.
@ast
Design of potent inhibitors of ...... lidation of a chimera peptide.
@en
Design of potent inhibitors of ...... lidation of a chimera peptide.
@nl
prefLabel
Design of potent inhibitors of ...... lidation of a chimera peptide.
@ast
Design of potent inhibitors of ...... lidation of a chimera peptide.
@en
Design of potent inhibitors of ...... lidation of a chimera peptide.
@nl
P2093
P2860
P356
P1476
Design of potent inhibitors of ...... lidation of a chimera peptide.
@en
P2093
Alicja Z Stasiak
Andrzej Stasiak
Axelle Renodon-Cornière
Julian Nomme
Kazuyasu Sakaguchi
Masayuki Takahashi
Yuya Asanomi
P2860
P304
P356
10.1021/JM1002974
P407
P50
P577
2010-08-01T00:00:00Z