UDP is a competitive antagonist at the human P2Y14 receptor
about
The purinergic neurotransmitter revisited: a single substance or multiple players?The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsDevelopment of selective agonists and antagonists of P2Y receptors.Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups.Role of spinal P2Y6 and P2Y11 receptors in neuropathic pain in rats: possible involvement of glial cells.Polyamidoamine (PAMAM) dendrimer conjugates of "clickable" agonists of the A3 adenosine receptor and coactivation of the P2Y14 receptor by a tethered nucleotide.Discovery of novel P2Y14 agonist and antagonist using conventional and nonconventional methods.Signalling and pharmacological properties of the P2Y receptor.Enhanced potency of nucleotide-dendrimer conjugates as agonists of the P2Y14 receptor: multivalent effect in G protein-coupled receptor recognition.The impact of commercially available purinergic ligands on purinergic signalling research.UDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiologic Consequences of P2Y14 Receptor Activation.The UDP-sugar-sensing P2Y(14) receptor promotes Rho-mediated signaling and chemotaxis in human neutrophils.A selective high-affinity antagonist of the P2Y14 receptor inhibits UDP-glucose-stimulated chemotaxis of human neutrophils.The nucleotide sugar UDP-glucose mobilizes long-term repopulating primitive hematopoietic cells.Synthesis and P2Y receptor activity of nucleoside 5'-phosphonate derivatives.Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli.Molecular recognition in the P2Y(14) receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucoseQuantification of Gi-mediated inhibition of adenylyl cyclase activity reveals that UDP is a potent agonist of the human P2Y14 receptor.Novel vasocontractile role of the P2Y₁₄ receptor: characterization of its signalling in porcine isolated pancreatic arteries.P2Y receptor subtypes evoke different Ca2+ signals in cultured aortic smooth muscle cellsGi-dependent cell signaling responses of the human P2Y14 receptor in model cell systemsCa(2+) signalling by P2Y receptors in cultured rat aortic smooth muscle cells.Secretion of matrix metalloproteinase-9 from astrocytes by inhibition of tonic P2Y14-receptor-mediated signal(s).
P2860
Q26824817-72683E24-54B3-41A7-A972-25BA80CBD8E0Q30486707-7126E61A-2899-4358-8E1E-D04FAFA47C0BQ33348980-C8DC9152-B5B1-4899-A2B0-890D6F2D85C7Q33584104-5A7DAB8E-C1DB-4218-BA55-322754D6443CQ33690286-680E26CA-AB1F-42C1-A829-1B526AD45982Q33754704-F576B36C-FEA6-4ECF-A957-643BAED7D44BQ33984656-929320F4-8869-47B1-8444-8AF0F8DAAFAFQ34033769-F72FB19B-ED6E-4DCE-9F0E-FAB851F9B960Q35020387-98253439-DF2D-4F65-B7D7-B5CE89AD3440Q35693550-DC29D2D6-2290-4A77-A068-323E2411DF8CQ35745912-3C88BFB8-8319-475A-9820-A33998260E33Q36308957-F2688682-9754-4B1D-9D78-ED3F48781733Q36935278-A53A2BCF-0911-49BF-8BA7-D60527601D19Q37052874-467FF3C7-0080-40EE-9EF0-B6D08DA6503DQ37290544-707EF297-74A2-4498-979F-F382207647D5Q37341915-EDED3C5D-BE17-4AA9-9AFE-4E066897EDF3Q37383623-6E69BF20-A855-43D0-8D81-978DF919AE75Q37444485-DE1B4879-4AD9-451C-A2BD-2CB3FD9BC7F4Q37671297-5FAD8EA0-CBAD-4BA9-A430-B220A82FA42CQ39319010-82124AEC-4457-4A32-94B8-7229FA2D6D6AQ39865234-277503C5-B939-44D8-BAAF-BFA20408E1C2Q42150644-ED45B908-7FA1-4826-A5E4-DCBDCD9DBB6CQ45419914-D6A507E5-A0A7-461A-BDE5-48480F35B14A
P2860
UDP is a competitive antagonist at the human P2Y14 receptor
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
UDP is a competitive antagonist at the human P2Y14 receptor
@ast
UDP is a competitive antagonist at the human P2Y14 receptor
@en
UDP is a competitive antagonist at the human P2Y14 receptor
@nl
type
label
UDP is a competitive antagonist at the human P2Y14 receptor
@ast
UDP is a competitive antagonist at the human P2Y14 receptor
@en
UDP is a competitive antagonist at the human P2Y14 receptor
@nl
prefLabel
UDP is a competitive antagonist at the human P2Y14 receptor
@ast
UDP is a competitive antagonist at the human P2Y14 receptor
@en
UDP is a competitive antagonist at the human P2Y14 receptor
@nl
P2093
P2860
P356
P1476
UDP is a competitive antagonist at the human P2Y14 receptor
@en
P2093
Eduardo R Lazarowski
Ingrid P Fricks
Rhonda L Carter
Robert A Nicholas
Savitri Maddileti
T Kendall Harden
P2860
P304
P356
10.1124/JPET.108.136309
P407
P577
2008-02-05T00:00:00Z