UDP is a competitive antagonist at the human P2Y14 receptor - Wikidata - wikimedia - TriplyDB

UDP is a competitive antagonist at the human P2Y14 receptor

UDP is a competitive antagonist at the human P2Y14 receptor

http://www.wikidata.org/entity/Q34053041

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The purinergic neurotransmitter revisited: a single substance or multiple players?The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors Development of selective agonists and antagonists of P2Y receptors.Human P2Y(14) receptor agonists: truncation of the hexose moiety of uridine-5'-diphosphoglucose and its replacement with alkyl and aryl groups.Role of spinal P2Y6 and P2Y11 receptors in neuropathic pain in rats: possible involvement of glial cells.Polyamidoamine (PAMAM) dendrimer conjugates of "clickable" agonists of the A3 adenosine receptor and coactivation of the P2Y14 receptor by a tethered nucleotide.Discovery of novel P2Y14 agonist and antagonist using conventional and nonconventional methods.Signalling and pharmacological properties of the P2Y receptor.Enhanced potency of nucleotide-dendrimer conjugates as agonists of the P2Y14 receptor: multivalent effect in G protein-coupled receptor recognition.The impact of commercially available purinergic ligands on purinergic signalling research.UDP-Sugars as Extracellular Signaling Molecules: Cellular and Physiologic Consequences of P2Y14 Receptor Activation.The UDP-sugar-sensing P2Y(14) receptor promotes Rho-mediated signaling and chemotaxis in human neutrophils.A selective high-affinity antagonist of the P2Y14 receptor inhibits UDP-glucose-stimulated chemotaxis of human neutrophils.The nucleotide sugar UDP-glucose mobilizes long-term repopulating primitive hematopoietic cells.Synthesis and P2Y receptor activity of nucleoside 5'-phosphonate derivatives.Pharmacological characterization of the P2 receptors profile in the podocytes of the freshly isolated rat glomeruli.Molecular recognition in the P2Y(14) receptor: Probing the structurally permissive terminal sugar moiety of uridine-5'-diphosphoglucose Quantification of Gi-mediated inhibition of adenylyl cyclase activity reveals that UDP is a potent agonist of the human P2Y14 receptor.Novel vasocontractile role of the P2Y₁₄ receptor: characterization of its signalling in porcine isolated pancreatic arteries.P2Y receptor subtypes evoke different Ca2+ signals in cultured aortic smooth muscle cells Gi-dependent cell signaling responses of the human P2Y14 receptor in model cell systems Ca(2+) signalling by P2Y receptors in cultured rat aortic smooth muscle cells.Secretion of matrix metalloproteinase-9 from astrocytes by inhibition of tonic P2Y14-receptor-mediated signal(s).

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P2860

UDP is a competitive antagonist at the human P2Y14 receptor

http://www.wikidata.org/entity/Q34053041

description

2008 nî lūn-bûn

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2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2008年の論文

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2008年論文

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2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

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2008年论文

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name

UDP is a competitive antagonist at the human P2Y14 receptor

@ast

UDP is a competitive antagonist at the human P2Y14 receptor

@en

UDP is a competitive antagonist at the human P2Y14 receptor

@nl

type

label

UDP is a competitive antagonist at the human P2Y14 receptor

@ast

UDP is a competitive antagonist at the human P2Y14 receptor

@en

UDP is a competitive antagonist at the human P2Y14 receptor

@nl

prefLabel

UDP is a competitive antagonist at the human P2Y14 receptor

@ast

UDP is a competitive antagonist at the human P2Y14 receptor

@en

UDP is a competitive antagonist at the human P2Y14 receptor

@nl

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JPET.108.136309

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Journal of Pharmacology and Experimental Therapeutics

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UDP is a competitive antagonist at the human P2Y14 receptor

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P2093

Eduardo R Lazarowski

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Ingrid P Fricks

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Rhonda L Carter

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Robert A Nicholas

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Savitri Maddileti

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T Kendall Harden

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P2860

A G protein-coupled receptor for UDP-glucose

Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase

Cloning, functional expression and tissue distribution of the human P2Y6 receptor

Positive inotropic effects by uridine triphosphate (UTP) and uridine diphosphate (UDP) via P2Y2 and P2Y6 receptors on cardiomyocytes and release of UTP in man during myocardial infarction

Agonist versus antagonist action of ATP at the P2Y4 receptor is determined by the second extracellular loop

Human immature monocyte-derived dendritic cells express the G protein-coupled receptor GPR105 (KIAA0001, P2Y14) and increase intracellular calcium in response to its agonist, uridine diphosphoglucose

Release of cellular UDP-glucose as a potential extracellular signaling molecule

Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription-polymerase chain reaction study

Differential coupling of the human P2Y(11) receptor to phospholipase C and adenylyl cyclase

Competitive inhibition by adenosine 5'-triphosphate of the actions on human platelets of 2-chloroadenosine 5'-diphosphate, 2-azidoadenosine 5'-diphosphate and 2-methylthioadenosine 5'-diphosphate

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588-594

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2

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325

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Kenneth A. Jacobson

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2008-02-05T00:00:00Z

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5599075

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