Pharmacophore-based discovery of FXR agonists. Part I: Model development and experimental validation.

Pharmacophore-based discovery of FXR agonists. Part I: Model development and experimental validation.

Item
http://www.wikidata.org/entity/Q34054283
Virtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid actionA combination of receptor-based pharmacophore modeling & QM techniques for identification of human chymase inhibitorsAccessing biological actions of Ganoderma secondary metabolites by in silico profilingIdentification of novel liver X receptor activators by structure-based modelingAn updated review on drug-induced cholestasis: mechanisms and investigation of physicochemical properties and pharmacokinetic parameters.Discovery of novel, non-acidic mPGES-1 inhibitors by virtual screening with a multistep protocol.Hit Identification of a Novel Dual Binder for h-telo/c-myc G-Quadruplex by a Combination of Pharmacophore Structure-Based Virtual Screening and Docking Refinement.Medicinal chemistry of farnesoid X receptor ligands: from agonists and antagonists to modulators.Characterizing ligands for farnesoid X receptor--available in vitro test systems for farnesoid X receptor modulator development.Identification of potential dual agonists of FXR and TGR5 using e-pharmacophore based virtual screening.Simultaneous diastereo- and enantioseparation of farnesoid X receptor (FXR) agonists with a quinine carbamate-based chiral stationary phase.Identification of InhA inhibitors: A combination of virtual screening, molecular dynamics simulations and quantum chemical studies.Discovery of new FXR agonists based on 6-ECDCA binding properties by virtual screening and molecular docking
P2860

Pharmacophore-based discovery of FXR agonists. Part I: Model development and experimental validation.

Item
http://www.wikidata.org/entity/Q34054283
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Pharmacophore-based discovery ...... t and experimental validation.
@ast
Pharmacophore-based discovery ...... t and experimental validation.
@en
Pharmacophore-based discovery ...... t and experimental validation.
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type
label
Pharmacophore-based discovery ...... t and experimental validation.
@ast
Pharmacophore-based discovery ...... t and experimental validation.
@en
Pharmacophore-based discovery ...... t and experimental validation.
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prefLabel
Pharmacophore-based discovery ...... t and experimental validation.
@ast
Pharmacophore-based discovery ...... t and experimental validation.
@en
Pharmacophore-based discovery ...... t and experimental validation.
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Pharmacophore-based discovery ...... t and experimental validation.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932