R1507, an anti-insulin-like growth factor-1 receptor (IGF-1R) antibody, and EWS/FLI-1 siRNA in Ewing's sarcoma: convergence at the IGF/IGFR/Akt axis

R1507, an anti-insulin-like growth factor-1 receptor (IGF-1R) antibody, and EWS/FLI-1 siRNA in Ewing's sarcoma: convergence at the IGF/IGFR/Akt axis

Item
http://www.wikidata.org/entity/Q34055933
Children's Oncology Group's 2013 blueprint for research: bone tumorsTeprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes.Can we unlock the potential of IGF-1R inhibition in cancer therapy?Growth-promoting role of the miR-106a~363 cluster in Ewing sarcoma.Novel secondary somatic mutations in Ewing's sarcoma and desmoplastic small round cell tumorsPI3K/AKT signaling modulates transcriptional expression of EWS/FLI1 through specificity protein 1.A kinase-independent biological activity for insulin growth factor-1 receptor (IGF-1R) : implications for inhibition of the IGF-1R signal.Preclinical evaluation of the PARP inhibitor, olaparib, in combination with cytotoxic chemotherapy in pediatric solid tumors.Ewing's sarcoma: overcoming the therapeutic plateau.Antitumor efficacy of the heparan sulfate mimic roneparstat (SST0001) against sarcoma models involves multi-target inhibition of receptor tyrosine kinases.Let-7a functions as a tumor suppressor in Ewing's sarcoma cell lines partly by targeting cyclin-dependent kinase 6.Targeted therapy in rare cancers--adopting the orphans.Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy.Prognostic and therapeutic relevance of the IGF pathway in Ewing's sarcoma patients.Identification of common and distinctive mechanisms of resistance to different anti-IGF-IR agents in Ewing's sarcoma.Type 1 insulin-like growth factor receptor targeted therapies in pediatric cancer.Significant association between cytotoxic T lymphocyte antigen 4 +49G>A polymorphism and risk of malignant bone tumors.
P2860

R1507, an anti-insulin-like growth factor-1 receptor (IGF-1R) antibody, and EWS/FLI-1 siRNA in Ewing's sarcoma: convergence at the IGF/IGFR/Akt axis

Item
http://www.wikidata.org/entity/Q34055933
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
R1507, an anti-insulin-like gr ...... gence at the IGF/IGFR/Akt axis
@ast
R1507, an anti-insulin-like gr ...... gence at the IGF/IGFR/Akt axis
@en
R1507, an anti-insulin-like gr ...... gence at the IGF/IGFR/Akt axis
@nl
type
label
R1507, an anti-insulin-like gr ...... gence at the IGF/IGFR/Akt axis
@ast
R1507, an anti-insulin-like gr ...... gence at the IGF/IGFR/Akt axis
@en
R1507, an anti-insulin-like gr ...... gence at the IGF/IGFR/Akt axis
@nl
prefLabel
R1507, an anti-insulin-like gr ...... gence at the IGF/IGFR/Akt axis
@ast
R1507, an anti-insulin-like gr ...... gence at the IGF/IGFR/Akt axis
@en
R1507, an anti-insulin-like gr ...... gence at the IGF/IGFR/Akt axis
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
P356
P1433
P1476
R1507, an anti-insulin-like gr ...... gence at the IGF/IGFR/Akt axis
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0026060
P407
P433
P478
P50
P577
P5875
P698
P921
P932