Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes. - Wikidata - wikimedia - TriplyDB

Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes.

Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes.

http://www.wikidata.org/entity/Q34130987

about

Rationale for therapeutic targeting insulin-like growth factor-1 receptor and bone marrow-derived fibrocytes in thyroid-associated ophthalmopathy Update on thyroid-associated Ophthalmopathy with a special emphasis on the ocular surface Teprotumumab for Thyroid-Associated Ophthalmopathy.Bidirectional TSH and IGF-1 receptor cross talk mediates stimulation of hyaluronan secretion by Graves' disease immunoglobins TSH-Mediated TNFα Production in Human Fibrocytes Is Inhibited by Teprotumumab, an IGF-1R Antagonist.CD40 Expression in Fibrocytes Is Induced by TSH: Potential Synergistic Immune Activation.Pentraxin-3 Is a TSH-Inducible Protein in Human Fibrocytes and Orbital Fibroblasts.Disrupted TSH Receptor Expression in Female Mouse Lung Fibroblasts Alters Subcellular IGF-1 Receptor Distribution.TSH-receptor-expressing fibrocytes and thyroid-associated ophthalmopathy.TSH/IGF-1 Receptor Cross Talk in Graves' Ophthalmopathy Pathogenesis.Advances in the management of thyroid eye diseases: An overview.Pathogenesis of thyroid eye disease: review and update on molecular mechanisms.Novel Therapies for Thyroid Autoimmune Diseases.Inhibiting thyrotropin/insulin-like growth factor 1 receptor crosstalk to treat Graves' ophthalmopathy: studies in orbital fibroblasts in vitro.TSHR as a therapeutic target in Graves' disease.Dysthyroid optic neuropathy: update on pathogenesis, diagnosis, and management.miR-29a-3p suppresses cell proliferation and migration by downregulating IGF1R in hepatocellular carcinoma.TSH/IGF-1 Receptor Cross-Talk Rapidly Activates Extracellular Signal-Regulated Kinases in Multiple Cell Types.New advances in understanding thyroid-associated ophthalmopathy and the potential role for insulin-like growth factor-I receptor.CD34- Orbital Fibroblasts From Patients With Thyroid-Associated Ophthalmopathy Modulate TNF-α Expression in CD34+ Fibroblasts and Fibrocytes.

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Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes.

http://www.wikidata.org/entity/Q34130987

description

2014 nî lūn-bûn

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2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

Teprotumumab, an IGF-1R blocki ...... nd IGF-1 action in fibrocytes.

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Teprotumumab, an IGF-1R blocki ...... nd IGF-1 action in fibrocytes.

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Teprotumumab, an IGF-1R blocki ...... nd IGF-1 action in fibrocytes.

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Teprotumumab, an IGF-1R blocki ...... nd IGF-1 action in fibrocytes.

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Teprotumumab, an IGF-1R blocki ...... nd IGF-1 action in fibrocytes.

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Teprotumumab, an IGF-1R blocki ...... nd IGF-1 action in fibrocytes.

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Teprotumumab, an IGF-1R blocki ...... nd IGF-1 action in fibrocytes.

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Teprotumumab, an IGF-1R blocki ...... nd IGF-1 action in fibrocytes.

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Teprotumumab, an IGF-1R blocki ...... nd IGF-1 action in fibrocytes.

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The Journal of Clinical Endocrinology and Metabolism

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Teprotumumab, an IGF-1R blocki ...... and IGF-1 action in fibrocytes

@en

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Courtney Y Kauh

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Hong Chen

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Nupur Raychaudhuri

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Shivani Gupta

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Tünde Mester

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P2860

A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.

Increased generation of fibrocytes in thyroid-associated ophthalmopathy.

Cytokines, Graves' disease, and thyroid-associated ophthalmopathy

R1507, an anti-insulin-like growth factor-1 receptor (IGF-1R) antibody, and EWS/FLI-1 siRNA in Ewing's sarcoma: convergence at the IGF/IGFR/Akt axis

Detection of alveolar fibrocytes in idiopathic pulmonary fibrosis and systemic sclerosis

Orbital fibroblasts exhibit a novel pattern of responses to proinflammatory cytokines: potential basis for the pathogenesis of thyroid-associated ophthalmopathy.

A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor

The role of the fibrocyte, a bone marrow-derived mesenchymal progenitor, in reactive and reparative fibroses.

Fibroblasts expressing the thyrotropin receptor overarch thyroid and orbit in Graves' disease.

A stimulatory thyrotropin receptor antibody enhances hyaluronic acid synthesis in graves' orbital fibroblasts: inhibition by an IGF-I receptor blocking antibody.

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E1635-40

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scholarly article

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10.1210/JC.2014-1580

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9

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Raymond S Douglas

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2014-05-30T00:00:00Z

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262956412

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24878056

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4154099

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