Assessing subunit dependency of the Plasmodium proteasome using small molecule inhibitors and active site probes
about
Artemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of Plasmodium parasitesTargeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistanceGlobal analysis of protein N-myristoylation and exploration of N-myristoyltransferase as a drug target in the neglected human pathogen Leishmania donovani.Covalent Tethering of Fragments For Covalent Probe DiscoveryStructure- and function-based design of Plasmodium-selective proteasome inhibitorsMonitoring Target Engagement of Deubiquitylating Enzymes Using Activity Probes: Past, Present, and Future.The cryo-EM structure of the Plasmodium falciparum 20S proteasome and its use in the fight against malaria.Activity-based probes for the multicatalytic proteasome.Targeting proteasomes in infectious organisms to combat disease.Proteases as antimalarial targets: strategies for genetic, chemical, and therapeutic validation.Protein Degradation Systems as Antimalarial Therapeutic Targets.Development of two novel high-throughput assays to quantify ubiquitylated proteins in cell lysates: application to screening of new anti-malarials.The Proteasome in Modern Drug Discovery: Second Life of a Highly Valuable Drug TargetRational Design of Proteasome Inhibitors as Antimalarial Drugs.Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery.Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance
P2860
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P2860
Assessing subunit dependency of the Plasmodium proteasome using small molecule inhibitors and active site probes
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Assessing subunit dependency o ...... ibitors and active site probes
@ast
Assessing subunit dependency o ...... ibitors and active site probes
@en
Assessing subunit dependency o ...... ibitors and active site probes
@nl
type
label
Assessing subunit dependency o ...... ibitors and active site probes
@ast
Assessing subunit dependency o ...... ibitors and active site probes
@en
Assessing subunit dependency o ...... ibitors and active site probes
@nl
prefLabel
Assessing subunit dependency o ...... ibitors and active site probes
@ast
Assessing subunit dependency o ...... ibitors and active site probes
@en
Assessing subunit dependency o ...... ibitors and active site probes
@nl
P2093
P2860
P50
P356
P1433
P1476
Assessing subunit dependency o ...... ibitors and active site probes
@en
P2093
Bogdan I Florea
Fiona E McAllister
Joshua E Elias
Kavitha Govindaswamy
Purnima Bhanot
Wouter A van der Linden
P2860
P304
P356
10.1021/CB5001263
P577
2014-06-19T00:00:00Z