Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance
about
Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparumArtemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of Plasmodium parasitesRecent advances in understanding apicomplexan parasitesGenome-wide association analysis identifies genetic loci associated with resistance to multiple antimalarials in Plasmodium falciparum from China-Myanmar borderPlasmodium falciparum: multifaceted resistance to artemisininsArtemisinin Action and Resistance in Plasmodium falciparumPlasmodium falciparum Maf1 Confers Survival upon Amino Acid StarvationLongitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistanceGenomic epidemiology of artemisinin resistant malariaLongitudinal study of Plasmodium pathogens identifies new loci associated with artemisinin resistance.The clinical impact of artemisinin resistance in Southeast Asia and the potential for future spread.Artemisinin resistance without pfkelch13 mutations in Plasmodium falciparum isolates from Cambodia.The Plasmodium PI(4)K inhibitor KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasitesA tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.Understanding artemisinin-resistant malaria: what a difference a year makesPlasmodium parasites mount an arrest response to dihydroartemisinin, as revealed by whole transcriptome shotgun sequencing (RNA-seq) and microarray study.Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisininsStructure- and function-based design of Plasmodium-selective proteasome inhibitorsAlternative methods for the Plasmodium falciparum artemisinin ring-stage survival assay with increased simplicity and parasite stage-specificity.Artemisinin-Resistant Plasmodium falciparum Malaria.Limited genetic diversity in the PvK12 Kelch protein in Plasmodium vivax isolates from Southeast AsiaAbsence of in vivo selection for K13 mutations after artemether-lumefantrine treatment in UgandaMalaria parasite clearance.Plasmodium falciparum kelch 13: a potential molecular marker for tackling artemisinin-resistant malaria parasites.Knockout of the peroxiredoxin 5 homologue PFAOP does not affect the artemisinin susceptibility of Plasmodium falciparum.Artemisinin as an anticancer drug: Recent advances in target profiling and mechanisms of action.Resisting resistance: is there a solution for malaria?The cryo-EM structure of the Plasmodium falciparum 20S proteasome and its use in the fight against malaria.Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort.A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile.Targeting proteasomes in infectious organisms to combat disease.Antimalarial Drug Resistance: A Threat to Malaria Elimination.Polymeric therapeutic delivery systems for the treatment of infectious diseases.Endoperoxide Drug Cross-Resistance Patterns for Plasmodium falciparum Exhibiting an Artemisinin Delayed-Clearance Phenotype.Protein Degradation Systems as Antimalarial Therapeutic Targets.Graphene oxide inhibits malaria parasite invasion and delays parasitic growth in vitro.Antimalarial drug resistance: linking Plasmodium falciparum parasite biology to the clinic.Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity.Host-mediated impairment of parasite maturation during blood-stage Plasmodium infection.Defining the Effectiveness of Antimalarial Chemotherapy: Investigation of the Lag in Parasite Clearance Following Drug Administration
P2860
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P2860
Targeting the cell stress response of Plasmodium falciparum to overcome artemisinin resistance
description
2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article scientifique
@fr
artículu científicu espublizáu en 2015
@ast
scientific article (publication date: April 2015)
@en
vedecký článok (publikovaný 2015-04)
@sk
vědecký článek publikovaný v roce 2015
@cs
wetenschappelijk artikel (gepubliceerd in 2015-04)
@nl
wissenschaftlicher Artikel
@de
наукова стаття, опублікована у квітні 2015
@uk
name
Targeting the cell stress resp ...... vercome artemisinin resistance
@ast
Targeting the cell stress resp ...... vercome artemisinin resistance
@en
Targeting the cell stress resp ...... vercome artemisinin resistance
@nl
type
label
Targeting the cell stress resp ...... vercome artemisinin resistance
@ast
Targeting the cell stress resp ...... vercome artemisinin resistance
@en
Targeting the cell stress resp ...... vercome artemisinin resistance
@nl
prefLabel
Targeting the cell stress resp ...... vercome artemisinin resistance
@ast
Targeting the cell stress resp ...... vercome artemisinin resistance
@en
Targeting the cell stress resp ...... vercome artemisinin resistance
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
Targeting the cell stress resp ...... vercome artemisinin resistance
@en
P2093
Con Dogovski
Gaetan Burgio
Judith Straimer
Julie A Simpson
Leann Tilley
Nectarios Klonis
Nina Gnädig
Shannon Kenny
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.1002132
P407
P50
P577
2015-04-01T00:00:00Z