TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model. - Wikidata - wikimedia - TriplyDB

TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model.

TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model.

http://www.wikidata.org/entity/Q34062681

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The T-box gene family: emerging roles in development, stem cells and cancer Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancer.Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex.Human breast progenitor cell numbers are regulated by WNT and TBX3.Transgenic mouse model expressing P53(R172H), luciferase, EGFP, and KRAS(G12D) in a single open reading frame for live imaging of tumor.Gli activity is critical at multiple stages of embryonic mammary and nipple development.The orthologous Tbx transcription factors Omb and TBX2 induce epithelial cell migration and extrusion in vivo without involvement of matrix metalloproteinases TOX3 is expressed in mammary ER(+) epithelial cells and regulates ER target genes in luminal breast cancer.Identification of a novel percent mammographic density locus at 12q24.TBX3 promotes human embryonic stem cell proliferation and neuroepithelial differentiation in a differentiation stage-dependent manner T-box3 is a ciliary protein and regulates stability of the Gli3 transcription factor to control digit number.Regulation of the T-box transcription factor Tbx3 by the tumour suppressor microRNA-206 in breast cancer.Illuminating cancer systems with genetically engineered mouse models and coupled luciferase reporters in vivo The T-box transcription factors TBX2 and TBX3 in mammary gland development and breast cancer The T-box transcription factor 3 is a promising biomarker and a key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypes SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication.Chemically induced specification of retinal ganglion cells from human embryonic and induced pluripotent stem cells.Regulation of organogenesis and stem cell properties by T-box transcription factors.Proliferation assays (BrdU and EdU) on skeletal tissue sections.Putative Breast Cancer Driver Mutations in TBX3 Cause Impaired Transcriptional Repression.Expression level of TBX3 gene in renal carcinoma and its clinical significance.

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TBX3 over-expression causes mammary gland hyperplasia and increases mammary stem-like cells in an inducible transgenic mouse model.

http://www.wikidata.org/entity/Q34062681

description

2011 nî lūn-bûn

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2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

TBX3 over-expression causes ma ...... ucible transgenic mouse model.

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TBX3 over-expression causes ma ...... ucible transgenic mouse model.

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TBX3 over-expression causes ma ...... ucible transgenic mouse model.

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TBX3 over-expression causes ma ...... ucible transgenic mouse model.

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TBX3 over-expression causes ma ...... ucible transgenic mouse model.

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TBX3 over-expression causes ma ...... ucible transgenic mouse model.

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TBX3 over-expression causes ma ...... ucible transgenic mouse model.

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TBX3 over-expression causes ma ...... ucible transgenic mouse model.

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1471-213X-11-65

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BMC Developmental Biology

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TBX3 over-expression causes ma ...... ucible transgenic mouse model.

@en

P2093

Andy Liu

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Gultekin Gulsen

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Jing Liu

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Taosheng Huang

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Taraneh Esmailpour

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Xiying Shang

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P2860

The T-box family

Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome

TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence

Tbx3 impinges on the p53 pathway to suppress apoptosis, facilitate cell transformation and block myogenic differentiation

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome

The spectrum of mutations in TBX3: Genotype/Phenotype relationship in ulnar-mammary syndrome.

Key stages in mammary gland development: the cues that regulate ductal branching morphogenesis.

The T-box repressors TBX2 and TBX3 specifically regulate the tumor suppressor gene p14ARF via a variant T-site in the initiator

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1471-213x-11-65

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10.1186/1471-213X-11-65

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2011-10-31T00:00:00Z

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