Biomimetic actinide chelators: an update on the preclinical development of the orally active hydroxypyridonate decorporation agents 3,4,3-LI(1,2-HOPO) and 5-LIO(Me-3,2-HOPO).
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Identification of process related trace level impurities in the actinide decorporation agent 3,4,3-LI(1,2-HOPO): Nozzle-skimmer fragmentation via ESI LC-QTOFMS.The role of chelation in the treatment of other metal poisonings.Characterization, HPLC method development and impurity identification for 3,4,3-LI(1,2-HOPO), a potent actinide chelator for radionuclide decorporation.In vitro metabolism and stability of the actinide chelating agent 3,4,3-LI(1,2-HOPO).New insights into structure and luminescence of Eu(III) and Sm(III) complexes of the 3,4,3-LI(1,2-HOPO) ligand.Siderocalin-mediated recognition, sensitization, and cellular uptake of actinidesDose-dependent efficacy and safety toxicology of hydroxypyridinonate actinide decorporation agents in rodents: towards a safe and effective human dosing regimen.Solution thermodynamic stability of complexes formed with the octadentate hydroxypyridinonate ligand 3,4,3-LI(1,2-HOPO): a critical feature for efficient chelation of lanthanide(IV) and actinide(IV) ions.3-Hydroxypyridinone derivatives as metal-sequestering agents for therapeutic use.Chelation therapy for treatment of systemic intoxication with uranium: A review.Actinide chelation: biodistribution and in vivo complex stability of the targeted metal ions.(238)Pu elimination profiles after delayed treatment with 3,4,3LI(1,2HOPO) in female and male Swiss-Webster mice.Multidentate terephthalamidate and hydroxypyridonate ligands: towards new orally active chelators.3,4,3-LI(1,2-HOPO): in vitro formation of highly stable lanthanide complexes translates into efficacious in vivo europium decorporation.Biodistribution of the multidentate hydroxypyridinonate ligand [(14) C]-3,4,3-LI(1,2-HOPO), a potent actinide decorporation agent.From early prophylaxis to delayed treatment: Establishing the plutonium decorporation activity window of hydroxypyridinonate chelating agents.Evaluating the potential of chelation therapy to prevent and treat gadolinium deposition from MRI contrast agents.Metallophores and Trace Metal Biogeochemistry
P2860
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P2860
Biomimetic actinide chelators: an update on the preclinical development of the orally active hydroxypyridonate decorporation agents 3,4,3-LI(1,2-HOPO) and 5-LIO(Me-3,2-HOPO).
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Biomimetic actinide chelators: ...... -HOPO) and 5-LIO(Me-3,2-HOPO).
@ast
Biomimetic actinide chelators: ...... -HOPO) and 5-LIO(Me-3,2-HOPO).
@en
Biomimetic actinide chelators: ...... -HOPO) and 5-LIO(Me-3,2-HOPO).
@nl
type
label
Biomimetic actinide chelators: ...... -HOPO) and 5-LIO(Me-3,2-HOPO).
@ast
Biomimetic actinide chelators: ...... -HOPO) and 5-LIO(Me-3,2-HOPO).
@en
Biomimetic actinide chelators: ...... -HOPO) and 5-LIO(Me-3,2-HOPO).
@nl
prefLabel
Biomimetic actinide chelators: ...... -HOPO) and 5-LIO(Me-3,2-HOPO).
@ast
Biomimetic actinide chelators: ...... -HOPO) and 5-LIO(Me-3,2-HOPO).
@en
Biomimetic actinide chelators: ...... -HOPO) and 5-LIO(Me-3,2-HOPO).
@nl
P2093
P2860
P1433
P1476
Biomimetic actinide chelators: ...... -HOPO) and 5-LIO(Me-3,2-HOPO).
@en
P2093
Birgitta Kullgren
Chris J Rosen
David K Shuh
Deborah I Bunin
Eleanor A Blakely
Kathleen A Bjornstad
Kenneth N Raymond
Patricia W Durbin
Polly Y Chang
P2860
P304
P356
10.1097/HP.0B013E3181C21273
P577
2010-09-01T00:00:00Z