Lauriston S. Taylor Lecture: the quest for therapeutic actinide chelators.
about
Using the antenna effect as a spectroscopic tool: photophysics and solution thermodynamics of the model luminescent hydroxypyridonate complex [Eu(III)(3,4,3-LI(1,2-HOPO))]-.Biomimetic actinide chelators: an update on the preclinical development of the orally active hydroxypyridonate decorporation agents 3,4,3-LI(1,2-HOPO) and 5-LIO(Me-3,2-HOPO).Identification of process related trace level impurities in the actinide decorporation agent 3,4,3-LI(1,2-HOPO): Nozzle-skimmer fragmentation via ESI LC-QTOFMS.The role of chelation in the treatment of other metal poisonings.On the use of X-ray absorption spectroscopy to elucidate the structure of lutetium adenosine mono- and triphosphate complexes.Characterization, HPLC method development and impurity identification for 3,4,3-LI(1,2-HOPO), a potent actinide chelator for radionuclide decorporation.Sodium bicarbonate protects uranium-induced acute nephrotoxicity through uranium-decorporation by urinary alkalinization in rats.Sensitizing curium luminescence through an antenna protein to investigate biological actinide transport mechanismsDose-dependent efficacy and safety toxicology of hydroxypyridinonate actinide decorporation agents in rodents: towards a safe and effective human dosing regimen.Solution thermodynamic stability of complexes formed with the octadentate hydroxypyridinonate ligand 3,4,3-LI(1,2-HOPO): a critical feature for efficient chelation of lanthanide(IV) and actinide(IV) ions.Actinide chelation: biodistribution and in vivo complex stability of the targeted metal ions.Pharmacological properties of orally available, amphipathic polyaminocarboxylic acid chelators for actinide decorporation.(238)Pu elimination profiles after delayed treatment with 3,4,3LI(1,2HOPO) in female and male Swiss-Webster mice.Texturing formulations for uranium skin decontamination.Multidentate terephthalamidate and hydroxypyridonate ligands: towards new orally active chelators.3,4,3-LI(1,2-HOPO): in vitro formation of highly stable lanthanide complexes translates into efficacious in vivo europium decorporation.Biodistribution of the multidentate hydroxypyridinonate ligand [(14) C]-3,4,3-LI(1,2-HOPO), a potent actinide decorporation agent.From early prophylaxis to delayed treatment: Establishing the plutonium decorporation activity window of hydroxypyridinonate chelating agents.Evaluating the potential of chelation therapy to prevent and treat gadolinium deposition from MRI contrast agents.The toxicological mechanisms and detoxification of depleted uranium exposure.Binding constant determination of uranyl-citrate complex by ACE using a multi-injection method
P2860
Q33866083-EB885847-21C8-4F44-BCD4-68A169BC70B8Q34064275-E3402AFC-A524-4842-8E21-EAB6A590118EQ34266594-68E7FAD7-6084-4CAE-B46C-C08D8FEE01C0Q34376795-059AF2D9-9EF3-4E86-8BEF-E0E4811D7301Q34751955-085D0D00-1E9D-48B5-8A5A-835C6853597AQ35039838-153C98E3-925C-44FB-8BC9-196F264CE6C5Q35649303-DD38FCE5-7B23-4EBE-A7FE-360A472D2D69Q36702166-5A1D9F47-AC08-4438-AE22-A6A4F529AA74Q36787963-4CC410C6-EDDD-458D-8EA0-689D62AD1F55Q37166814-AFD038A0-68BD-48BA-B4D1-F53C1E88D55BQ39556737-9FA7F827-F451-4996-89CA-2426D7A3C6A8Q41937662-E3FD9E4D-8B54-4061-9A96-732EE4EF5E31Q43452617-614FEFD6-611F-4978-AE89-ED2D959AED27Q43736823-02CBBEA1-1186-4BD0-891A-EDF53E50C5FFQ46957159-95C244C7-5CF6-4E67-8C99-D493BC3097A5Q50529124-C2EAC864-6C61-4A0A-81DC-6007EB4FF547Q51035615-D710A05A-78E4-4DB9-9DB4-8C7BEA110EFFQ53132183-633BBFFA-5339-4A20-9AC5-80B6F6881F07Q55016125-A58B3533-B460-4349-9B19-54058E9ECADEQ55037631-441BA6B3-A280-4981-A772-68B79519E932Q57342986-251FC473-BA65-439D-932D-0BC35078398C
P2860
Lauriston S. Taylor Lecture: the quest for therapeutic actinide chelators.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Lauriston S. Taylor Lecture: the quest for therapeutic actinide chelators.
@en
Lauriston S. Taylor Lecture: the quest for therapeutic actinide chelators.
@nl
type
label
Lauriston S. Taylor Lecture: the quest for therapeutic actinide chelators.
@en
Lauriston S. Taylor Lecture: the quest for therapeutic actinide chelators.
@nl
prefLabel
Lauriston S. Taylor Lecture: the quest for therapeutic actinide chelators.
@en
Lauriston S. Taylor Lecture: the quest for therapeutic actinide chelators.
@nl
P1433
P1476
Lauriston S. Taylor Lecture: the quest for therapeutic actinide chelators.
@en
P2093
Patricia W Durbin
P304
P356
10.1097/01.HP.0000326345.41816.C2
P577
2008-11-01T00:00:00Z