Tip links in hair cells: molecular composition and role in hearing loss. - Wikidata - wikimedia - TriplyDB

Tip links in hair cells: molecular composition and role in hearing loss.

Tip links in hair cells: molecular composition and role in hearing loss.

http://www.wikidata.org/entity/Q34066652

about

Integrating the biophysical and molecular mechanisms of auditory hair cell mechanotransduction Proteomic analysis of the enterocyte brush border Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransduction The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice TMHS is an integral component of the mechanotransduction machinery of cochlear hair cells Noise-induced hearing loss: new animal models.Rapid positional cloning of zebrafish mutations by linkage and homozygosity mapping using whole-genome sequencing.Biophysical mechanisms underlying outer hair cell loss associated with a shortened tectorial membrane.Molecular biology of hearing.Hearing loss alters quantal release at cochlear nucleus stellate cells.Linking LIMK1 deficiency to hyperacusis and progressive hearing loss in individuals with Williams syndrome Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2 Cadherin-23 mediates heterotypic cell-cell adhesion between breast cancer epithelial cells and fibroblasts Targeted next generation sequencing for molecular diagnosis of Usher syndrome.Myosin motor function: the ins and outs of actin-based membrane protrusions.Unconventional mechanics of lipid membranes: a potential role for mechanotransduction of hair cell stereocilia.Spatio-temporally restricted expression of cell adhesion molecules during chicken embryonic development TMC1 and TMC2 Localize at the Site of Mechanotransduction in Mammalian Inner Ear Hair Cell Stereocilia USH1G with unique retinal findings caused by a novel truncating mutation identified by genome-wide linkage analysis.Usher protein functions in hair cells and photoreceptors.Gene expression profiles of the cochlea and vestibular endorgans: localization and function of genes causing deafness.Adhesion GPCRs as a Putative Class of Metabotropic Mechanosensors.Functional effects of adult human olfactory stem cells on early-onset sensorineural hearing loss.

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P2860

Tip links in hair cells: molecular composition and role in hearing loss.

http://www.wikidata.org/entity/Q34066652

description

2009 nî lūn-bûn

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2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

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2009年論文

@zh-tw

2009年论文

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name

Tip links in hair cells: molecular composition and role in hearing loss.

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Tip links in hair cells: molecular composition and role in hearing loss.

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Tip links in hair cells: molecular composition and role in hearing loss.

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type

label

Tip links in hair cells: molecular composition and role in hearing loss.

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Tip links in hair cells: molecular composition and role in hearing loss.

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Tip links in hair cells: molecular composition and role in hearing loss.

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prefLabel

Tip links in hair cells: molecular composition and role in hearing loss.

@ast

Tip links in hair cells: molecular composition and role in hearing loss.

@en

Tip links in hair cells: molecular composition and role in hearing loss.

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MOO.0B013E3283303472

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Current Opinion in Otolaryngology & Head and Neck Surgery

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Tip links in hair cells: molecular composition and role in hearing loss.

@en

P2093

Bechara Kachar

http://www.w3.org/2001/XMLSchema#string

Hirofumi Sakaguchi

http://www.w3.org/2001/XMLSchema#string

Joshua Tokita

http://www.w3.org/2001/XMLSchema#string

Ulrich Müller

http://www.w3.org/2001/XMLSchema#string

P2860

A defect in harmonin, a PDZ domain-containing protein expressed in the inner ear sensory hair cells, underlies Usher syndrome type 1C

Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D

Mutations of the protocadherin gene PCDH15 cause Usher syndrome type 1F

Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F

Usher syndrome type I G (USH1G) is caused by mutations in the gene encoding SANS, a protein that associates with the USH1C protein, harmonin

PCDH15 is expressed in the neurosensory epithelium of the eye and ear and mutant alleles are responsible for both USH1F and DFNB23

Defective myosin VIIA gene responsible for Usher syndrome type 1B

Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle.

Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of the novel cadherin-like gene CDH23

The Usher syndrome proteins cadherin 23 and harmonin form a complex by means of PDZ-domain interactions.

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388-393

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scholarly article

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10.1097/MOO.0B013E3283303472

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5

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17

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2009-10-01T00:00:00Z

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19633555

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2921850

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