Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML - Wikidata - wikimedia - TriplyDB

Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML

Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML

http://www.wikidata.org/entity/Q34072688

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Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins Prolyl isomerase Pin1 in cancer The yeast Ess1 prolyl isomerase controls Swi6 and Whi5 nuclear localization.KSHV reactivation and novel implications of protein isomerization on lytic switch control Global Cell Proteome Profiling, Phospho-signaling and Quantitative Proteomics for Identification of New Biomarkers in Acute Myeloid Leukemia Patients Pin1-mediated Runx2 modification is critical for skeletal development The roles of peptidyl-proline isomerases in gene regulation.C/EBPα regulated microRNA-34a targets E2F3 during granulopoiesis and is down-regulated in AML with CEBPA mutations Connectedness of PPI network neighborhoods identifies regulatory hub proteins.Restoration of CCAAT enhancer binding protein α P42 induces myeloid differentiation and overcomes all-trans retinoic acid resistance in human acute promyelocytic leukemia NB4-R1 cells.C/EBPα-p30 protein induces expression of the oncogenic long non-coding RNA UCA1 in acute myeloid leukemia Up-regulation of translation eukaryotic initiation factor 4E in nucleophosmin 1 haploinsufficient cells results in changes in CCAAT enhancer-binding protein α activity: implications in myelodysplastic syndrome and acute myeloid leukemia.Lenalidomide-mediated enhanced translation of C/EBPα-p30 protein up-regulates expression of the antileukemic microRNA-181a in acute myeloid leukemia Transcription factor C/EBPα-induced microRNA-30c inactivates Notch1 during granulopoiesis and is downregulated in acute myeloid leukemia Oncogenic roles of PRL-3 in FLT3-ITD induced acute myeloid leukaemia.Pin1 modulates ERα levels in breast cancer through inhibition of phosphorylation-dependent ubiquitination and degradation.PI3-kinase/p38 kinase-dependent E2F1 activation is critical for Pin1 induction in tamoxifen-resistant breast cancer cells A noncanonical Flt3ITD/NF-κB signaling pathway represses DAPK1 in acute myeloid leukemia.The role of PIN1 on odontogenic and adipogenic differentiation in human dental pulp stem cells.c-Myc suppresses miR-451⊣YWTAZ/AKT axis via recruiting HDAC3 in acute myeloid leukemia.Proteomic approaches in myeloid leukemia.Peptidyl-prolyl cis-trans isomerase Pin1 in ageing, cancer and Alzheimer disease.Proteomics approaches for myeloid leukemia drug discovery.Resolving the functions of peptidylprolyl isomerases: insights from the mutagenesis of the nuclear FKBP25 enzyme.The isomerase PIN1 controls numerous cancer-driving pathways and is a unique drug target.Deguelin, a selective silencer of the NPM1 mutant, potentiates apoptosis and induces differentiation in AML cells carrying the NPM1 mutation.Pin1 interacts with the Epstein-Barr virus DNA polymerase catalytic subunit and regulates viral DNA replication.C/EBPα deregulation as a paradigm for leukemogenesis.The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia.Comparative proteomics in acute myeloid leukemia.Pin1 inhibition exerts potent activity against acute myeloid leukemia through blocking multiple cancer-driving pathways.BCR-ABL enhances the prolyl isomerase activity of Pin 1 by interacting with DAPK1 in ph+ ALL.Inhibition of Casein Kinase 2 Disrupts Differentiation of Myeloid Cells in Cancer and Enhances the Efficacy of Immunotherapy in Mice Prolyl isomerase Pin1: a promoter of cancer and a target for therapy Gears-In-Motion: The Interplay of WW and PPIase Domains in Pin1

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Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AML

http://www.wikidata.org/entity/Q34072688

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Elevated PIN1 expression by C/ ...... entiation through c-Jun in AML

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Elevated PIN1 expression by C/ ...... entiation through c-Jun in AML

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Elevated PIN1 expression by C/ ...... entiation through c-Jun in AML

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Elevated PIN1 expression by C/ ...... entiation through c-Jun in AML

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Elevated PIN1 expression by C/ ...... entiation through c-Jun in AML

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Elevated PIN1 expression by C/ ...... entiation through c-Jun in AML

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Elevated PIN1 expression by C/ ...... entiation through c-Jun in AML

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Elevated PIN1 expression by C/ ...... entiation through c-Jun in AML

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Elevated PIN1 expression by C/ ...... entiation through c-Jun in AML

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A Kawasaki

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A Ryo

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Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia

Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

A human peptidyl-prolyl isomerase essential for regulation of mitosis

Phosphorylation-dependent proline isomerization catalyzed by Pin1 is essential for tumor cell survival and entry into mitosis

Phosphorylation-specific prolyl isomerization: is there an underlying theme?

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

The MADS transcription factor Mef2c is a pivotal modulator of myeloid cell fate

E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo

Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha

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