Phosphorylation-dependent proline isomerization catalyzed by Pin1 is essential for tumor cell survival and entry into mitosis
about
Nerve growth factor stimulates interaction of Cayman ataxia protein BNIP-H/Caytaxin with peptidyl-prolyl isomerase Pin1 in differentiating neuronsPin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c-Jun towards cyclin D1.Small family with key contacts: par14 and par17 parvulin proteins, relatives of pin1, now emerge in biomedical researchPin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism?The prolyl isomerase Pin1 in breast development and cancerStructural Basis for High-Affinity Peptide Inhibition of Human Pin1Understanding the role of PIN1 in hepatocellular carcinomaPin1: a molecular orchestrator in the heart.Membrane permeable cyclic peptidyl inhibitors against human Peptidylprolyl Isomerase Pin1.Peptidyl-prolyl isomerase Pin1 is a cellular factor required for hepatitis C virus propagation.Elevated PIN1 expression by C/EBPalpha-p30 blocks C/EBPalpha-induced granulocytic differentiation through c-Jun in AMLPin1 regulates centrosome duplication, and its overexpression induces centrosome amplification, chromosome instability, and oncogenesisSubnuclear compartmentalization of transiently expressed polyadenylated pri-microRNAs: processing at transcription sites or accumulation in SC35 foci.Peptidyl-prolyl isomerases: a new twist to transcription.Pin1-mediated Sp1 phosphorylation by CDK1 increases Sp1 stability and decreases its DNA-binding activity during mitosis.Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis.Proteasomal degradation of human peptidyl prolyl isomerase pin1-pointing phospho Bcl2 toward dephosphorylation.Prevalent overexpression of prolyl isomerase Pin1 in human cancersComplete determination of the Pin1 catalytic domain thermodynamic cycle by NMR lineshape analysis.Complete thermodynamic and kinetic characterization of the isomer-specific interaction between Pin1-WW domain and the amyloid precursor protein cytoplasmic tail phosphorylated at Thr668.Overexpressed cyclophilin B suppresses apoptosis associated with ROS and Ca2+ homeostasis after ER stress.Antioxidation of Cerium Oxide Nanoparticles to Several Series of Oxidative Damage Related to Type II Diabetes Mellitus In VitroPin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's disease.Increased expression of PIN1 gene in papillary thyroid carcinoma.A phosphorylated prodrug for the inhibition of Pin1.Overexpression of PvPin1, a Bamboo Homolog of PIN1-Type Parvulin 1, Delays Flowering Time in Transgenic Arabidopsis and Rice.Activation of beta-catenin signaling in prostate cancer by peptidyl-prolyl isomerase Pin1-mediated abrogation of the androgen receptor-beta-catenin interaction.
P2860
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P2860
Phosphorylation-dependent proline isomerization catalyzed by Pin1 is essential for tumor cell survival and entry into mitosis
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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Phosphorylation-dependent prol ...... urvival and entry into mitosis
@ast
Phosphorylation-dependent prol ...... urvival and entry into mitosis
@en
Phosphorylation-dependent prol ...... urvival and entry into mitosis
@nl
type
label
Phosphorylation-dependent prol ...... urvival and entry into mitosis
@ast
Phosphorylation-dependent prol ...... urvival and entry into mitosis
@en
Phosphorylation-dependent prol ...... urvival and entry into mitosis
@nl
prefLabel
Phosphorylation-dependent prol ...... urvival and entry into mitosis
@ast
Phosphorylation-dependent prol ...... urvival and entry into mitosis
@en
Phosphorylation-dependent prol ...... urvival and entry into mitosis
@nl
P2093
P3181
P1476
Phosphorylation-dependent prol ...... urvival and entry into mitosis
@en
P2093
B Guilliard
J F Rippmann
P Garin-Chesa
W J Rettig
P304
P3181
P407
P577
2000-07-01T00:00:00Z