Spectroscopic studies of substrate interactions with clavaminate synthase 2, a multifunctional alpha-KG-dependent non-heme iron enzyme: correlation with mechanisms and reactivities.
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Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alphaThe structural basis of cephalosporin formation in a mononuclear ferrous enzymeStructural Basis of Regiospecificity of a Mononuclear Iron Enzyme in Antibiotic Fosfomycin BiosynthesisThe Fe(II)/α-ketoglutarate-dependent taurine dioxygenases from Pseudomonas putida and Escherichia coli are tetramersMechanism of the C5 Stereoinversion Reaction in the Biosynthesis of Carbapenem AntibioticsStructure of the Dioxygenase AsqJ: Mechanistic Insights into a One-Pot Multistep Quinolone Antibiotic BiosynthesisMechanistic studies on three 2-oxoglutarate-dependent oxygenases of flavonoid biosynthesis: anthocyanidin synthase, flavonol synthase, and flavanone 3beta-hydroxylaseCatalytic Mechanisms of Fe(II)- and 2-Oxoglutarate-dependent OxygenasesStructure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum diseaseInhibition of 2-oxoglutarate dependent oxygenasesImposing function down a (cupin)-barrel: secondary structure and metal stereochemistry in the αKG-dependent oxygenases.Near-IR MCD of the nonheme ferrous active site in naphthalene 1,2-dioxygenase: correlation to crystallography and structural insight into the mechanism of Rieske dioxygenases.The crystal structure of a high-spin oxoiron(IV) complex and characterization of its self-decay pathwayStructural insight into antibiotic fosfomycin biosynthesis by a mononuclear iron enzyme.Non-heme Fe(IV)-oxo intermediates.The rate-limiting step of O2 activation in the α-ketoglutarate oxygenase factor inhibiting hypoxia inducible factor.Non-heme iron enzymes: contrasts to heme catalysisInterconversion of two oxidized forms of taurine/alpha-ketoglutarate dioxygenase, a non-heme iron hydroxylase: evidence for bicarbonate binding.Spectroscopic and electronic structure studies of aromatic electrophilic attack and hydrogen-atom abstraction by non-heme iron enzymesDirect spectroscopic detection of a C-H-cleaving high-spin Fe(IV) complex in a prolyl-4-hydroxylase.Substrate-mediated oxygen activation by homoprotocatechuate 2,3-dioxygenase: intermediates formed by a tyrosine 257 variant.Structural basis for the enantiospecificities of R- and S-specific phenoxypropionate/alpha-ketoglutarate dioxygenases.Inverse solvent isotope effects demonstrate slow aquo release from hypoxia inducible factor-prolyl hydroxylase (PHD2)Parallel and competitive pathways for substrate desaturation, hydroxylation, and radical rearrangement by the non-heme diiron hydroxylase AlkB.Mechanistic insights into the bifunctional non-heme iron oxygenase carbapenem synthase by active site saturation mutagenesisRevisiting the biosynthesis of dehydrophos reveals a tRNA-dependent pathway.Substrate-triggered formation and remarkable stability of the C-H bond-cleaving chloroferryl intermediate in the aliphatic halogenase, SyrB2Substrate-triggered addition of dioxygen to the diferrous cofactor of aldehyde-deformylating oxygenase to form a diferric-peroxide intermediate.Novel Approaches for the Accumulation of Oxygenated Intermediates to Multi-Millimolar Concentrations.The function and catalysis of 2-oxoglutarate-dependent oxygenases involved in plant flavonoid biosynthesis.Electronic structure analysis of the oxygen-activation mechanism by Fe(II)- and α-ketoglutarate (αKG)-dependent dioxygenases.Spectroscopic analyses of 2-oxoglutarate-dependent oxygenases: TauD as a case study.Dioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants.The facial triad in the α-ketoglutarate dependent oxygenase FIH: A role for sterics in linking substrate binding to O2 activation.Inverse solvent isotope effects arising from substrate triggering in the factor inhibiting hypoxia inducible factorUncoupled O2-activation in the human HIF-asparaginyl hydroxylase, FIH, does not produce reactive oxygen species.Substrate positioning by Gln(239) stimulates turnover in factor inhibiting HIF, an αKG-dependent hydroxylase.CD and MCD of CytC3 and taurine dioxygenase: role of the facial triad in alpha-KG-dependent oxygenases.Mechanism and Catalytic Diversity of Rieske Non-Heme Iron-Dependent Oxygenases.Auto-hydroxylation of FIH-1: an Fe(ii), alpha-ketoglutarate-dependent human hypoxia sensor.
P2860
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P2860
Spectroscopic studies of substrate interactions with clavaminate synthase 2, a multifunctional alpha-KG-dependent non-heme iron enzyme: correlation with mechanisms and reactivities.
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Spectroscopic studies of subst ...... h mechanisms and reactivities.
@ast
Spectroscopic studies of subst ...... h mechanisms and reactivities.
@en
Spectroscopic studies of subst ...... h mechanisms and reactivities.
@nl
type
label
Spectroscopic studies of subst ...... h mechanisms and reactivities.
@ast
Spectroscopic studies of subst ...... h mechanisms and reactivities.
@en
Spectroscopic studies of subst ...... h mechanisms and reactivities.
@nl
prefLabel
Spectroscopic studies of subst ...... h mechanisms and reactivities.
@ast
Spectroscopic studies of subst ...... h mechanisms and reactivities.
@en
Spectroscopic studies of subst ...... h mechanisms and reactivities.
@nl
P2093
P356
P1476
Spectroscopic studies of subst ...... h mechanisms and reactivities.
@en
P2093
B O Bachmann
C A Townsend
E I Solomon
P304
P356
10.1021/JA004025+
P407
P577
2001-08-01T00:00:00Z