PBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer.
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Mechanisms of oestrogen receptor (ER) gene regulation in breast cancerSimilarities between the Epstein-Barr Virus (EBV) Nuclear Protein EBNA1 and the Pioneer Transcription Factor FoxA: Is EBNA1 a "Bookmarking" Oncoprotein that Alters the Host Cell Epigenotype?Cooperating transcription factors mediate the function of estrogen receptorDifferential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasionIdentification of inherited genetic variations influencing prognosis in early-onset breast cancerDynamic estrogen receptor interactomes control estrogen-responsive trefoil Factor (TFF) locus cell-specific activities.Heregulin Co-opts PR Transcriptional Action Via Stat3 Role As a Coregulator to Drive Cancer Growth.PBX1 is a favorable prognostic biomarker as it modulates 13-cis retinoic acid-mediated differentiation in neuroblastoma.Identification of PBX1 target genes in cancer cells by global mapping of PBX1 binding sites.Estrogen receptor coregulators and pioneer factors: the orchestrators of mammary gland cell fate and development.HOX genes and their role in the development of human cancers.SOX4 mediates TGF-β-induced expression of mesenchymal markers during mammary cell epithelial to mesenchymal transition.PI3K pathway regulates ER-dependent transcription in breast cancer through the epigenetic regulator KMT2D.ChIP-seq and beyond: new and improved methodologies to detect and characterize protein-DNA interactions.Lipid-induced epigenomic changes in human macrophages identify a coronary artery disease-associated variant that regulates PPAP2B Expression through Altered C/EBP-beta binding.Retrovirus-Mediated Expression of E2A-PBX1 Blocks Lymphoid Fate but Permits Retention of Myeloid Potential in Early Hematopoietic Progenitors.Estrogen receptor alpha signaling promotes Sle1-induced loss of tolerance and immune cell activation and is responsible for sex bias in B6.Sle1 congenic mice.Research resource: whole-genome estrogen receptor α binding in mouse uterine tissue revealed by ChIP-seq.HOXB7 Is an ERα Cofactor in the Activation of HER2 and Multiple ER Target Genes Leading to Endocrine Resistance.Overexpression of lipid metabolism genes and PBX1 in the contralateral breasts of women with estrogen receptor-negative breast cancer.The pioneer factor PBX1 is a novel driver of metastatic progression in ERα-positive breast cancerThe Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1.Estrogen receptors and human disease: an update.RARγ is essential for retinoic acid induced chromatin remodeling and transcriptional activation in embryonic stem cellsInvestigation of the effects of estrogen on skeletal gene expression during zebrafish larval head development.Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer.Endocrine resistance in breast cancer: from cellular signaling pathways to epigenetic mechanisms.Epigenetic regulation of estrogen signaling in breast cancerPbx1 is required for adult subventricular zone neurogenesis.Estrogen represses gene expression through reconfiguring chromatin structures.A Common Docking Domain in Progesterone Receptor-B links DUSP6 and CK2 signaling to proliferative transcriptional programs in breast cancer cellsBenzoquinone from Fusarium pigment inhibits the proliferation of estrogen receptor-positive MCF-7 cells through the NF-κB pathway via estrogen receptor signaling.FOXC1 is involved in ERα silencing by counteracting GATA3 binding and is implicated in endocrine resistance.Pancancer modelling predicts the context-specific impact of somatic mutations on transcriptional programs.Integrative analysis of 1q23.3 copy-number gain in metastatic urothelial carcinoma.The gep proto-oncogene Gα12 mediates LPA-stimulated activation of CREB in ovarian cancer cells.Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer.Chromatin landscape and endocrine response in breast cancer.Approaches for assessing and discovering protein interactions in cancer.Glimpse into Hox and tale regulation of cell differentiation and reprogramming.
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P2860
PBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer.
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
PBX1 genomic pioneer function ...... progression in breast cancer.
@ast
PBX1 genomic pioneer function ...... progression in breast cancer.
@en
PBX1 genomic pioneer function ...... progression in breast cancer.
@nl
type
label
PBX1 genomic pioneer function ...... progression in breast cancer.
@ast
PBX1 genomic pioneer function ...... progression in breast cancer.
@en
PBX1 genomic pioneer function ...... progression in breast cancer.
@nl
prefLabel
PBX1 genomic pioneer function ...... progression in breast cancer.
@ast
PBX1 genomic pioneer function ...... progression in breast cancer.
@en
PBX1 genomic pioneer function ...... progression in breast cancer.
@nl
P2860
P1433
P1476
PBX1 genomic pioneer function ...... g progression in breast cancer
@en
P2093
Elizabeth B Ballantyne
Xiaoyang Zhang
P2860
P304
P356
10.1371/JOURNAL.PGEN.1002368
P577
2011-11-17T00:00:00Z