Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
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An induced rebinding model of antigen discriminationWIPI-Mediated Autophagy and LongevityExperimental and theoretical bases for mechanisms of antigen discrimination by T cellsSystems model of T cell receptor proximal signaling reveals emergent ultrasensitivity.Mechanical modulation of receptor-ligand interactions at cell-cell interfaces.Interplay between T cell receptor binding kinetics and the level of cognate peptide presented by major histocompatibility complexes governs CD8+ T cell responsiveness.Multisite Phosphorylation Modulates the T Cell Receptor ζ-Chain Potency but not the Switchlike Response.Cellular-level versus receptor-level response threshold hierarchies in T-cell activation.Structure-Based, Rational Design of T Cell Receptors.Can non-lytic CD8+ T cells drive HIV-1 escape?Architecture of a minimal signaling pathway explains the T-cell response to a 1 million-fold variation in antigen affinity and dose.2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system.Heterogeneity assessment of functional T cell avidity.Non-catalytic tyrosine-phosphorylated receptors.Mathematical Models for Immunology: Current State of the Art and Future Research Directions.T lymphocytes need less than 3 min to discriminate between peptide MHCs with similar TCR-binding parameters.Improved ligand discrimination by force-induced unbinding of the T cell receptor from peptide-MHC.Meeting report: Signal transduction meets systems biology.Coreceptor scanning by the T cell receptor provides a mechanism for T cell tolerance.TCR/pMHC Interaction: Phenotypic Model for an Unsolved Enigma.A stochastic T cell response criterion.The Serial Engagement Model 17 Years After: From TCR Triggering to Immunotherapy.PD-L1 blockade enhances response of pancreatic ductal adenocarcinoma to radiotherapy.Comparison of T Cell Activities Mediated by Human TCRs and CARs That Use the Same Recognition Domains.
P2860
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P2860
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
@ast
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
@en
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
@nl
type
label
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
@ast
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
@en
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
@nl
prefLabel
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
@ast
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
@en
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
@nl
P2093
P2860
P50
P1433
P1476
Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation.
@en
P2093
Ji-Li Chen
Milos Aleksic
Yan-Chun Peng
P2860
P356
10.1126/SCISIGNAL.2001430
P50
P577
2011-06-07T00:00:00Z