2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system.
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Identifying Individual T Cell Receptors of Optimal Avidity for Tumor AntigensLower Affinity T Cells are Critical Components and Active Participants of the Immune ResponseAccumulation of serial forces on TCR and CD8 frequently applied by agonist antigenic peptides embedded in MHC molecules triggers calcium in T cells.Progression of relapsing-remitting demyelinating disease does not require increased TCR affinity or epitope spreadViral Escape Mutant Epitope Maintains TCR Affinity for Antigen yet Curtails CD8 T Cell Responses.Force-Regulated In Situ TCR-Peptide-Bound MHC Class II Kinetics Determine Functions of CD4+ T Cells.Normalized Synergy Predicts That CD8 Co-Receptor Contribution to T Cell Receptor (TCR) and pMHC Binding Decreases As TCR Affinity Increases in Human Viral-Specific T Cells.In situ and in silico kinetic analyses of programmed cell death-1 (PD-1) receptor, programmed cell death ligands, and B7-1 protein interaction network.Two-Dimensional Analysis of Cross-Junctional Molecular Interaction by Force Probes.Local Cellular and Cytokine Cues in the Spleen Regulate In Situ T Cell Receptor Affinity, Function, and Fate of CD8+ T Cells.The cellular environment regulates in situ kinetics of T-cell receptor interaction with peptide major histocompatibility complex.Relative Movements of Domains in Large Molecules of the Immune System.Accumulation of dynamic catch bonds between TCR and agonist peptide-MHC triggers T cell signaling.Dual Biomembrane Force Probe enables single-cell mechanical analysis of signal crosstalk between multiple molecular species.Generation of higher affinity T cell receptors by antigen-driven differentiation of progenitor T cells in vitro.Receptor-mediated cell mechanosensing.Binding constant of cell adhesion receptors and substrate-immobilized ligands depends on the distribution of ligands.Study of protein structural deformations under external mechanical perturbations by a coarse-grained simulation method.2D Kinetic Analysis of TCR and CD8 Coreceptor for LCMV GP33 Epitopes
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2D TCR-pMHC-CD8 kinetics determines T-cell responses in a self-antigen-specific TCR system.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 20 October 2013
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
2D TCR-pMHC-CD8 kinetics deter ...... f-antigen-specific TCR system.
@en
2D TCR-pMHC-CD8 kinetics deter ...... f-antigen-specific TCR system.
@nl
type
label
2D TCR-pMHC-CD8 kinetics deter ...... f-antigen-specific TCR system.
@en
2D TCR-pMHC-CD8 kinetics deter ...... f-antigen-specific TCR system.
@nl
prefLabel
2D TCR-pMHC-CD8 kinetics deter ...... f-antigen-specific TCR system.
@en
2D TCR-pMHC-CD8 kinetics deter ...... f-antigen-specific TCR system.
@nl
P2093
P2860
P356
P1476
2D TCR-pMHC-CD8 kinetics deter ...... lf-antigen-specific TCR system
@en
P2093
Karolina Malecek
Laura A Johnson
Michelle Krogsgaard
Steven A Rosenberg
P2860
P304
P356
10.1002/EJI.201343774
P407
P50
P577
2013-10-20T00:00:00Z