Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells.
about
MSRE-PCR for analysis of gene-specific DNA methylationDNA methylation-independent reversion of gemcitabine resistance by hydralazine in cervical cancer cellsImportant roles of multiple Sp1 binding sites and epigenetic modifications in the regulation of the methionine sulfoxide reductase B1 (MsrB1) promoterQuantitative correlation between promoter methylation and messenger RNA levels of the reduced folate carrierDrug resistance in cancer: an overview.The reduced folate carrier (RFC) is cytotoxic to cells under conditions of severe folate deprivation. RFC as a double edged sword in folate homeostasisHypermethylation of the human proton-coupled folate transporter (SLC46A1) minimal transcriptional regulatory region in an antifolate-resistant HeLa cell line.Resistance to antifolates.Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targeting.Simultaneous Analysis of Wnt and NF-κB Signaling Pathways in Doxorubicin Sensitive and Methotrexate Resistant PLC/ PRF/5 CellsArray-based multiplex analysis of DNA methylation in breast cancer tissues.Paradoxical impact of two folate receptors, FRα and RFC, in ovarian cancer: effect on cell proliferation, invasion and clinical outcome.Polymorphisms and methylation of the reduced folate carrier in osteosarcoma.The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer.DCTPP1 attenuates the sensitivity of human gastric cancer cells to 5-fluorouracil by up-regulating MDR1 expression epigenetically.Genetic and epigenetic predictors of responsiveness to treatment in RA.Heterogeneous response of different tumor cell lines to methotrexate-coupled nanoparticles in presence of hyperthermia.Alterations in the expression of transcription factors and the reduced folate carrier as a novel mechanism of antifolate resistance in human leukemia cells.DNA Methylation of ADME Genes.Methotrexate-grafted-oligochitosan micelles as drug carriers: synthesis and biological evaluations.Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation.Impact of hyperhomocysteinemia on breast cancer initiation and progression: epigenetic perspective.Determinants of orofacial clefting II: Effects of 5-Aza-2'-deoxycytidine on gene methylation during development of the first branchial arch.MicroRNA-mediated drug resistance in ovarian cancer.Genetic and epigenetic alterations of the reduced folate carrier in untreated diffuse large B-cell lymphoma.Roles of USF, Ikaros and Sp proteins in the transcriptional regulation of the human reduced folate carrier B promoter.Genetic and epigenetic alterations of the APC gene in malignant melanoma.Severe hypoxia induces complete antifolate resistance in carcinoma cells due to cell cycle arrest.Regulation of multidrug resistance in cancer cells by hyaluronan.Aberrant methylation in the promoter region of the reduced folate carrier gene is a potential mechanism of resistance to methotrexate in primary central nervous system lymphomas.Structure and regulation of the murine reduced folate carrier gene: identification of four noncoding exons and promoters and regulation by dietary folates.Coupling to a cancer-selective heparan-sulfate-targeted branched peptide can by-pass breast cancer cell resistance to methotrexate.Targeting the Epigenome as a Novel Therapeutic Approach for Breast Cancer.Adoptive cancer immunotherapy using DNA-demethylated T helper cells as antigen-presenting cells.Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models
P2860
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P2860
Methylation-dependent silencing of the reduced folate carrier gene in inherently methotrexate-resistant human breast cancer cells.
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Methylation-dependent silencin ...... ant human breast cancer cells.
@ast
Methylation-dependent silencin ...... ant human breast cancer cells.
@en
Methylation-dependent silencin ...... ant human breast cancer cells.
@nl
type
label
Methylation-dependent silencin ...... ant human breast cancer cells.
@ast
Methylation-dependent silencin ...... ant human breast cancer cells.
@en
Methylation-dependent silencin ...... ant human breast cancer cells.
@nl
prefLabel
Methylation-dependent silencin ...... ant human breast cancer cells.
@ast
Methylation-dependent silencin ...... ant human breast cancer cells.
@en
Methylation-dependent silencin ...... ant human breast cancer cells.
@nl
P2093
P2860
P356
P1476
Methylation-dependent silencin ...... ant human breast cancer cells.
@en
P2093
A F Kirkin
K N Dzhandzhugazyan
P Guldberg
P2860
P304
39990-40000
P356
10.1074/JBC.M103181200
P407
P577
2001-08-16T00:00:00Z