DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
about
Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9The human Rad9 checkpoint protein stimulates the carbamoyl phosphate synthetase activity of the multifunctional protein CADLoading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitroStructure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1USP37 deubiquitinates Cdt1 and contributes to regulate DNA replicationRad9A is required for G2 decatenation checkpoint and to prevent endoreduplication in response to topoisomerase II inhibitionGenotoxin-induced Rad9-Hus1-Rad1 (9-1-1) chromatin association is an early checkpoint signaling event.A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage.Tousled-like kinase-dependent phosphorylation of Rad9 plays a role in cell cycle progression and G2/M checkpoint exit.Contributions of Rad9 to tumorigenesis.Regulation of NEIL1 protein abundance by RAD9 is important for efficient base excision repairChk1 Activation Protects Rad9A from Degradation as Part of a Positive Feedback Loop during Checkpoint Signalling.Candidate protein biodosimeters of human exposure to ionizing radiation.The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1.Caspase-3-mediated cleavage of Rad9 during apoptosis.A role for the phosphorylation of hRad9 in checkpoint signaling.Phosphorylation of human Rad9 is required for genotoxin-activated checkpoint signaling.Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethalityThe Tousled-Like Kinases as Guardians of Genome IntegrityE2A-PBX1 interacts directly with the KIX domain of CBP/p300 in the induction of proliferation in primary hematopoietic cells.Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.Application of hRad9 in lung cancer treatment as a molecular marker and a molecular target.
P2860
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P2860
DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
@ast
DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
@en
DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
@nl
type
label
DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
@ast
DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
@en
DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
@nl
prefLabel
DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
@ast
DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
@en
DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
@nl
P2093
P2860
P356
P1476
DNA damage-dependent and -independent phosphorylation of the hRad9 checkpoint protein.
@en
P2093
P2860
P304
41898-41905
P356
10.1074/JBC.M105152200
P407
P577
2001-09-10T00:00:00Z