Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection. - Wikidata - wikimedia - TriplyDB

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

http://www.wikidata.org/entity/Q34093225

about

HTLV-1 tax specific CD8+ T cells express low levels of Tim-3 in HTLV-1 infection: implications for progression to neurological complications Role of PD-1 in HIV pathogenesis and as target for therapy Immune Checkpoint Modulators: An Emerging Antiglioma Armamentarium Restoring homeostasis of CD4⁺ T cells in hepatitis-B-virus-related liver fibrosis Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators Molecular and cellular insights into T cell exhaustion Overcoming T cell exhaustion in infection and cancer The Regulation of CD4(+) T Cell Responses during Protozoan Infections Leveraging fluorinated glucosamine action to boost antitumor immunity The enduring tale of T cells in HIV immunopathogenesis Functional classification of memory CD8(+) T cells by CX3CR1 expression.Memory T cells in transplantation - progress and challenges.Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints.Regulation of immunity during visceral Leishmania infection Innate and Adaptive Immune Regulation During Chronic Viral Infections TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway Age-related expansion of Tim-3 expressing T cells in vertically HIV-1 infected children Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection T cell Ig and mucin domain-containing protein 3 is recruited to the immune synapse, disrupts stable synapse formation, and associates with receptor phosphatases Tsc1 promotes the differentiation of memory CD8+ T cells via orchestrating the transcriptional and metabolic programs PD-1, PD-L1 and PD-L2 Gene Expression on T-Cells and Natural Killer Cells Declines in Conjunction with a Reduction in PD-1 Protein during the Intensive Phase of Tuberculosis Treatment DNA/MVA Vaccination of HIV-1 Infected Participants with Viral Suppression on Antiretroviral Therapy, followed by Treatment Interruption: Elicitation of Immune Responses without Control of Re-Emergent Virus Programmed Cell Death-1/Programmed Death-ligand 1 Pathway: A New Target for Sepsis Blimp-1-mediated CD4 T cell exhaustion causes CD8 T cell dysfunction during chronic toxoplasmosis.Liver-primed CD8+ T cells suppress antiviral adaptive immunity through galectin-9-independent T-cell immunoglobulin and mucin 3 engagement of high-mobility group box 1 in mice.Prospects for treatment of latent HIV.HIV-1 Vaccine Trials: Evolving Concepts and Designs Tim-3 negatively regulates IL-12 expression by monocytes in HCV infection.The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia Influenza-specific T cells from older people are enriched in the late effector subset and their presence inversely correlates with vaccine response.CD40 activation rescues antiviral CD8⁺ T cells from PD-1-mediated exhaustion.Tissue-resident exhausted effector memory CD8+ T cells accumulate in the retina during chronic experimental autoimmune uveoretinitis.In vitro and in vivo antivirus activity of an anti-programmed death-ligand 1 (PD-L1) rat-bovine chimeric antibody against bovine leukemia virus infection.Association of T-cell immunoglobulin and mucin domain-containing molecule 3 (Tim-3) polymorphisms with susceptibility and disease progression of HBV infection.Reversal of NK-cell exhaustion in advanced melanoma by Tim-3 blockade.Cancer immunotherapy by targeting immune checkpoints: mechanism of T cell dysfunction in cancer immunity and new therapeutic targets.IL-21-mediated reversal of NK cell exhaustion facilitates anti-tumour immunity in MHC class I-deficient tumours Proliferation conditions promote intrinsic changes in NK cells for an IL-10 response.Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of γδ T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia.

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P2860

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

http://www.wikidata.org/entity/Q34093225

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

@ast

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

@en

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

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type

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Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

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Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

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Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

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Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

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Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

@en

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

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PNAS.1009731107

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Proceedings of the National Academy of Sciences of the United States of America

P1476

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.

@en

P2093

Ana C Anderson

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Erin E West

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Gordon J Freeman

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Hyun-Tak Jin

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Koichi Araki

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Rafi Ahmed

http://www.w3.org/2001/XMLSchema#string

Vijay K Kuchroo

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Wendy G Tan

http://www.w3.org/2001/XMLSchema#string

P2860

Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection

PD-1 and its ligands in tolerance and immunity

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

Restoring function in exhausted CD8 T cells during chronic viral infection

Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance

Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells

Tissue-specific differences in PD-1 and PD-L1 expression during chronic viral infection: implications for CD8 T-cell exhaustion

Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination.

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease.

Memory CD8 T-cell differentiation during viral infection.

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14733-14738

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10.1073/PNAS.1009731107

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107

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