mTORC1 links protein quality and quantity control by sensing chaperone availability. - Wikidata - wikimedia - TriplyDB

mTORC1 links protein quality and quantity control by sensing chaperone availability.

mTORC1 links protein quality and quantity control by sensing chaperone availability.

http://www.wikidata.org/entity/Q34094616

about

DRiPs solidify: progress in understanding endogenous MHC class I antigen processing Therapeutic Manipulation of Ageing: Repurposing Old Dogs and Discovering New Tricks Amino acid analog toxicity in primary rat neuronal and astrocyte cultures: implications for protein misfolding and TDP-43 regulation Organismal proteostasis: role of cell-nonautonomous regulation and transcellular chaperone signaling.The stress of protein misfolding: from single cells to multicellular organisms Cellular stress response pathways and ageing: intricate molecular relationships Premature translational termination products are rapidly degraded substrates for MHC class I presentation The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation.Inhibition of mammalian target of rapamycin signaling by CCI-779 (temsirolimus) induces growth inhibition and cell cycle arrest in Cashmere goat fetal fibroblasts (Capra hircus).HSF1: Guardian of Proteostasis in Cancer Cotranslational response to proteotoxic stress by elongation pausing of ribosomes.HSF1 critically attunes proteotoxic stress sensing by mTORC1 to combat stress and promote growth.mTOR signaling in protein homeostasis: less is more?Mammalian TOR signaling to the AGC kinases.Targeting the PI3K/Akt/mTOR signalling pathway in Cystic Fibrosis Co-translational mechanisms of quality control of newly synthesized polypeptides.HSF1 deficiency and impaired HSP90-dependent protein folding are hallmarks of aneuploid human cells.mTORC1 senses stresses: Coupling stress to proteostasis.β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice.TORC1-mediated sensing of chaperone activity alters glucose metabolism and extends lifespan.The case for therapeutic proteostasis modulators Regulation of mTORC1 complex assembly and signaling by GRp58/ERp57.Inhibition of protein synthesis by TOR inactivation revealed a conserved regulatory mechanism of the BiP chaperone in Chlamydomonas.Degradation of the endoplasmic reticulum by autophagy during endoplasmic reticulum stress in Arabidopsis.mTORC Inhibitors as Broad-Spectrum Therapeutics for Age-Related Diseases

P2860

Q27006750-E90E7F92-092A-4691-8079-04831D88ED48 Q28069996-633944C2-2D9D-472C-9AF3-6024A3609D93 Q28564723-D770561F-4757-4C44-8B61-7E34E306C176 Q33917420-DE47ACEE-36FC-4161-8D66-47C124A37721 Q34181891-BC48A524-848A-4F96-8FF0-BEBF36F26A4C Q34185656-4F72F3FA-C403-4AAC-8880-AEDF6699CFF5 Q34517453-6293ACB2-2972-4209-BBBE-3E74132AA873 Q35458694-B3E0548B-42B4-4642-810C-3CDAEBE79D03 Q36045128-0B8ED611-1324-45E0-A32B-6230F1902C72 Q36490084-94C57ABE-82DB-483A-B9F5-A89E6073B0CC Q36604984-D669BA6E-D045-49D8-B3BF-6DAB23659787 Q37686982-BF583373-454F-4DB8-B10D-F2E4CA3B3C20 Q37873702-9A487192-03E0-469F-838C-2AA3C7B9D35A Q37943416-CF771424-5B46-45E4-9DE3-06C39873293F Q38631561-9E40FE19-B08C-472A-A824-7B22958E09E2 Q38700656-5EBA7286-6959-4E42-8BF4-14317FA48E24 Q38957897-AEDBE51A-2577-4075-A0F7-072264793F92 Q39179555-39C66B5B-03FF-45FC-B21F-5675E281D5B5 Q40969425-AC3E49EC-DD22-48F1-8FA5-3F5BFAD5398B Q41628978-AA96B661-5641-4F7D-BAF0-BB44035D1D91 Q42245016-D0E32C00-44BB-4F75-A4CF-5144B3B7F5E0 Q42779914-9C503025-1BD8-43FE-B747-4153E48F0089 Q50514761-C92013F8-E94B-4A50-902E-EA63B46AE250 Q53759239-058CA947-F945-4F22-B90C-E0671EDF1D17 Q58795101-7A335FB9-5915-41D3-B607-E20B2C35C7DA

P2860

mTORC1 links protein quality and quantity control by sensing chaperone availability.

http://www.wikidata.org/entity/Q34094616

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

mTORC1 links protein quality and quantity control by sensing chaperone availability.

@ast

mTORC1 links protein quality and quantity control by sensing chaperone availability.

@en

mTORC1 links protein quality and quantity control by sensing chaperone availability.

@nl

type

label

mTORC1 links protein quality and quantity control by sensing chaperone availability.

@ast

mTORC1 links protein quality and quantity control by sensing chaperone availability.

@en

mTORC1 links protein quality and quantity control by sensing chaperone availability.

@nl

prefLabel

mTORC1 links protein quality and quantity control by sensing chaperone availability.

@ast

mTORC1 links protein quality and quantity control by sensing chaperone availability.

@en

mTORC1 links protein quality and quantity control by sensing chaperone availability.

@nl

P1433

Q34094616-606F37A2-2368-4B3D-A10C-58BE5879EEAE

P1476

Q34094616-E8262393-36D1-43BB-8422-97F42616435B

P2093

Q34094616-0BE27959-77DD-4F4B-B038-5D736A70EFE1

Q34094616-20CE29CF-3526-4691-AF96-EC562E458898

Q34094616-A0826F14-FDBB-45FF-9BC0-F4CD474D7FC3

Q34094616-A3BE4ACC-1C7F-4B50-98E3-09FF67D41990

Q34094616-FA496513-C549-4FD8-BD62-B430342A4889

P2860

Q34094616-1220CFDD-A2B2-426D-A6B0-C0EBC3222C7E

Q34094616-12D11FE3-C796-46B7-844E-A958B1D298AD

Q34094616-13987EF7-56BF-4E3A-9316-5879C0D89A72

Q34094616-13E683FE-304F-419E-B31E-484F2528F3C1

Q34094616-15B53215-C873-46B2-A29E-6DEABE454E0A

Q34094616-17F9DC60-42B3-4212-94EC-822D22898A57

Q34094616-23300099-B968-4053-9CAD-7DE2434AFE35

Q34094616-3086D594-C0AF-4A13-82E2-C3ACD3E315A8

Q34094616-343A31E4-0050-4D2D-B9B0-414A8F1ED9A3

Q34094616-3DA59C79-20C0-49B3-AA08-55FA0E79E721

P304

Q34094616-98D4988E-0D5F-41BB-9C55-9B80340A84D7

P31

Q34094616-58E27DDA-FAA5-4E3B-9165-3A93B6B24FB7

P356

Q34094616-C348013A-72D6-4AAF-BB56-E22D7DA1AC25

P407

Q34094616-C9595223-DCE2-4F97-BC27-6443F3AADD61

P433

Q34094616-F349FA45-4F1A-4F14-95CA-D79C88B0D56E

P478

Q34094616-38803BEF-C7C5-4C28-A835-7E6554FC21EC

P50

Q34094616-1A28ADFD-1B40-4EAF-A68E-F9F010617533

P577

Q34094616-6035423F-13F8-4670-BDDD-3C02C7D840B7

P698

Q34094616-A46FF72F-E2FD-43BB-9846-535E2601C3A4

P921

Q34094616-B991127A-77D4-4FAA-B468-EECCBFA4E377

P932

Q34094616-8727C8C3-A653-4D3C-9199-5B8D54A09DC2

P356

JBC.M110.120295

P1433

Journal of Biological Chemistry

P1476

mTORC1 links protein quality and quantity control by sensing chaperone availability.

@en

P2093

Cam Patterson

http://www.w3.org/2001/XMLSchema#string

Jack R Bennink

http://www.w3.org/2001/XMLSchema#string

Jun Sun

http://www.w3.org/2001/XMLSchema#string

Shu-Bing Qian

http://www.w3.org/2001/XMLSchema#string

Xingqian Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Differential role of hydrogen peroxide in UV-induced signal transduction.

Ultraviolet-induced phosphorylation of p70(S6k) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase c

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

Suppression of the mTOR-raptor signaling pathway by the inhibitor of heat shock protein 90 geldanamycin

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

TOR signaling in growth and metabolism

P304

27385-27395

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M110.120295

http://www.w3.org/2001/XMLSchema#string

P407

P433

35

http://www.w3.org/2001/XMLSchema#string

P478

285

http://www.w3.org/2001/XMLSchema#string

P50

Jonathan W Yewdell

P577

2010-07-06T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

20605781

http://www.w3.org/2001/XMLSchema#string

P921

molecular chaperones

P932

2930736

http://www.w3.org/2001/XMLSchema#string