The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity. - Wikidata - wikimedia - TriplyDB

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

http://www.wikidata.org/entity/Q34097297

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A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7 Interleukin-33 and Mast Cells Bridge Innate and Adaptive Immunity: From the Allergologist's Perspective Autoantigen Microarray for High-throughput Autoantibody Profiling in Systemic Lupus Erythematosus Regulation of nuclear factor-κB in autoimmunity Deconstructing innate immune signaling in myelodysplastic syndromes Regulation of NF-κB by ubiquitination TNFAIP3 promotes survival of CD4 T cells by restricting MTOR and promoting autophagy Linear ubiquitination in immunity The immunogenetics of Behçet's disease: A comprehensive review Does antigen masking by ubiquitin chains protect from the development of autoimmune diseases?The Trypanosoma cruzi protease cruzain mediates immune evasion An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunity Genome wide transcriptome analysis of dendritic cells identifies genes with altered expression in psoriasis.B-cell tolerance regulates production of antibodies causing heparin-induced thrombocytopenia.Three single nucleotide polymorphisms of TNFAIP3 gene increase the risk of rheumatoid arthritis.Hypomorphic A20 expression confers susceptibility to psoriasis.Molecular control of steady-state dendritic cell maturation and immune homeostasis.The tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) imposes a brake on antitumor activity of CD8 T cells A20 (Tnfaip3) deficiency in myeloid cells protects against influenza A virus infection.Intestinal epithelial expression of TNFAIP3 results in microbial invasion of the inner mucus layer and induces colitis in IL-10-deficient mice.Ubiquitin makes its mark on immune regulation.Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimmune disease.A20 restricts wnt signaling in intestinal epithelial cells and suppresses colon carcinogenesis.Protein ubiquitination in lymphoid malignancies.A20 restricts ubiquitination of pro-interleukin-1β protein complexes and suppresses NLRP3 inflammasome activity.Autophagy enhances NFκB activity in specific tissue macrophages by sequestering A20 to boost antifungal immunity.Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.Lack of the ubiquitin-editing enzyme A20 results in loss of hematopoietic stem cell quiescence HCV infection and B-cell lymphomagenesis B-cell-intrinsic hepatitis C virus expression leads to B-cell-lymphomagenesis and induction of NF-κB signalling.Targeting lymphocyte signaling pathways as a therapeutic approach to systemic lupus erythematosus.Polyubiquitin binding to ABIN1 is required to prevent autoimmunity.Neurodegenerative and inflammatory pathway components linked to TNF-α/TNFR1 signaling in the glaucomatous human retina.The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis LKB1 inhibition of NF-κB in B cells prevents T follicular helper cell differentiation and germinal center formation.Characteristics of A20 gene polymorphisms and clinical significance in patients with rheumatoid arthritis Mechanisms of B cell autoimmunity in SLE.Ubiquitin-specific protease 4 mitigates Toll-like/interleukin-1 receptor signaling and regulates innate immune activation.Meta-analysis of the TNFAIP3 region in psoriasis reveals a risk haplotype that is distinct from other autoimmune diseases

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P2860

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

http://www.wikidata.org/entity/Q34097297

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

@ast

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

@en

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

@nl

type

label

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

@ast

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

@en

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

@nl

prefLabel

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

@ast

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

@en

The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity.

@nl

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J.IMMUNI.2010.07.017

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The ubiquitin modifying enzyme A20 restricts B cell survival and prevents autoimmunity

@en

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Averil Ma

http://www.w3.org/2001/XMLSchema#string

Barbara A Malynn

http://www.w3.org/2001/XMLSchema#string

Chih L Liu

http://www.w3.org/2001/XMLSchema#string

Clifford A Lowell

http://www.w3.org/2001/XMLSchema#string

Julio Barrera

http://www.w3.org/2001/XMLSchema#string

Lesley Rhee

http://www.w3.org/2001/XMLSchema#string

Patrizia Scapini

http://www.w3.org/2001/XMLSchema#string

Paul J Utz

http://www.w3.org/2001/XMLSchema#string

Rommel Advincula

http://www.w3.org/2001/XMLSchema#string

P2860

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

Significance analysis of microarrays applied to the ionizing radiation response

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein

The ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signals

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

Shared principles in NF-kappaB signaling

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements.

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181-191

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scholarly article

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10.1016/J.IMMUNI.2010.07.017

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2

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20705491

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2931361

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