Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner.
about
The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferationA Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase geneStructural insights into gene repression by the orphan nuclear receptor SHPThe orphan nuclear receptor LRH-1 activates the ABCG5/ABCG8 intergenic promoterInterleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependentThe fetoprotein transcription factor (FTF) gene is essential to embryogenesis and cholesterol homeostasis and is regulated by a DR4 elementLRH-1 drives colon cancer cell growth by repressing the expression of the CDKN1A gene in a p53-dependent manner.Role of nuclear receptor SHP in metabolism and cancer.Combined deletion of Fxr and Shp in mice induces Cyp17a1 and results in juvenile onset cholestasis.Structural and biochemical basis for selective repression of the orphan nuclear receptor liver receptor homolog 1 by small heterodimer partner.Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screeningLoss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesisOrphan nuclear receptor small heterodimer partner inhibits angiotensin II- stimulated PAI-1 expression in vascular smooth muscle cells.E1A and a nuclear receptor corepressor splice variant (N-CoRI) are thyroid hormone receptor coactivators that bind in the corepressor mode.Nuclear receptors: mediators and modifiers of inflammation-induced cholestasis.Liver receptor homolog 1 controls the expression of carboxyl ester lipase.Sodium arsenite induces orphan nuclear receptor SHP gene expression via AMP-activated protein kinase to inhibit gluconeogenic enzyme gene expression.Nuclear receptors. I. Nuclear receptors and bile acid homeostasis.Does loss of bile acid homeostasis make mice melancholy?Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes.Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism.The orphan nuclear receptor small heterodimer partner is required for thiazolidinedione effects in leptin-deficient mice.A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways.Coregulator interactions with the thyroid hormone receptor.LRH-1-dependent glucose sensing determines intermediary metabolism in liver.Liver receptor homolog-1 (LRH-1): a potential therapeutic target for cancerCompromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1.Thyroid Hormone Regulates the mRNA Expression of Small Heterodimer Partner through Liver Receptor Homolog-1FXR and PXR: potential therapeutic targets in cholestasis.Emerging actions of the nuclear receptor LRH-1 in the gut.Enhanced ethanol catabolism in orphan nuclear receptor SHP-null mice.The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP.Cell signaling and nuclear receptors: new opportunities for molecular pharmaceuticals in liver disease.Bile acid signal-induced phosphorylation of small heterodimer partner by protein kinase Cζ is critical for epigenomic regulation of liver metabolic genesCritical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.Bile acid signaling pathways increase stability of Small Heterodimer Partner (SHP) by inhibiting ubiquitin-proteasomal degradation.The orphan nuclear receptor SHP inhibits apoptosis during the monocytic differentiation by inducing p21WAF1.The role of FXR in disorders of bile acid homeostasis.The orphan nuclear receptor SHP attenuates renal fibrosis.Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis.
P2860
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P2860
Dual mechanisms for repression of the monomeric orphan receptor liver receptor homologous protein-1 by the orphan small heterodimer partner.
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Dual mechanisms for repression ...... han small heterodimer partner.
@ast
Dual mechanisms for repression ...... han small heterodimer partner.
@en
Dual mechanisms for repression ...... han small heterodimer partner.
@nl
type
label
Dual mechanisms for repression ...... han small heterodimer partner.
@ast
Dual mechanisms for repression ...... han small heterodimer partner.
@en
Dual mechanisms for repression ...... han small heterodimer partner.
@nl
prefLabel
Dual mechanisms for repression ...... han small heterodimer partner.
@ast
Dual mechanisms for repression ...... han small heterodimer partner.
@en
Dual mechanisms for repression ...... han small heterodimer partner.
@nl
P2860
P356
P1476
Dual mechanisms for repression ...... han small heterodimer partner.
@en
P2093
David D Moore
Yoon-Kwang Lee
P2860
P304
P356
10.1074/JBC.M105161200
P407
P577
2001-10-19T00:00:00Z