Homoharringtonine: history, current research, and future direction. - Wikidata - wikimedia - TriplyDB

Homoharringtonine: history, current research, and future direction.

Homoharringtonine: history, current research, and future direction.

http://www.wikidata.org/entity/Q34105271

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Harnessing the apoptotic programs in cancer stem-like cells U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:The continuing search for antitumor agents from higher plants Omacetaxine: a protein translation inhibitor for treatment of chronic myelogenous leukemia Homoharringtonine suppresses imatinib resistance via the Bcl-6/p53 pathway in chronic myeloid leukemia cell lines Potential of plant-derived natural products in the treatment of leukemia and lymphoma Natural products from Cephalotaxus sp.: chemical diversity and synthetic aspects.Eukaryotic protein synthesis inhibitors identified by comparison of cytotoxicity profiles.Anticancer Alkaloids from Trees: Development into Drugs.Screening of allergic components mediated by H(1)R in homoharringtonine injection through H(1)R/CMC-HPLC/MS.A comparative proteomic study of Homoharringtonine-induced apoptosis in leukemia K562 cells.Drug discovery from natural sources.Chronic myeloid leukemia: mechanisms of resistance and treatment.Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells.Emerging therapeutics targeting mRNA translation Dasatinib: the emerging evidence of its potential in the treatment of chronic myeloid leukemia.Personalized medical treatment strategies for patients with chronic myeloid leukemia.A phase I dose-finding and pharmacokinetic study of subcutaneous semisynthetic homoharringtonine (ssHHT) in patients with advanced acute myeloid leukaemia.Synthesis of antiproliferative Cephalotaxus esters and their evaluation against several human hematopoietic and solid tumor cell lines: uncovering differential susceptibilities to multidrug resistance A phase II open-label study of the intravenous administration of homoharringtonine in the treatment of myelodysplastic syndrome Homoharringtonine for the treatment of chronic myelogenous leukemia.Homoharringtonine/omacetaxine mepesuccinate: the long and winding road to food and drug administration approval Pharmacokinetics and excretion of (14)C-omacetaxine in patients with advanced solid tumors Inhibitory effects of omacetaxine on leukemic stem cells and BCR-ABL-induced chronic myeloid leukemia and acute lymphoblastic leukemia in mice Novel therapeutic agents against cancer stem cells of chronic myeloid leukemia.Homoharringtonine acts synergistically with SG235-TRAIL, a conditionally replicating adenovirus, in human leukemia cell lines.Anticancer drugs from traditional toxic Chinese medicines.Omacetaxine mepesuccinate (synribo) - newly launched in chronic myeloid leukemia.Ester alkaloids from Cephalotaxus interfere with the 2'3'-cGAMP-induced type I interferon pathway in vitro.Preparation and in vivo safety evaluations of antileukemic homoharringtonine-loaded PEGylated liposomes.Riproximin modulates multiple signaling cascades leading to cytostatic and apoptotic effects in human breast cancer cells.Homoharringtonine induces apoptosis and growth arrest in human myeloma cells.2-[1'-(Benz-yloxy)spiro-[indane-1,2'-pyrrolidine]-5'-yl]aceto-nitrile.Long term curative effects of sequential therapy with all-trans retinoic acid, arsenious oxide and chemotherapy on patients with acute promyelocytic leukemia.The plant alkaloid and anti-leukemia drug homoharringtonine sensitizes resistant human colorectal carcinoma cells to TRAIL-induced apoptosis via multiple mechanisms.Therapeutic experience of adult acute myeloid leukemia in a single institution of China and its relationship with chromosome karyotype.Metabolism of homoharringtonine, a cytotoxic component of the evergreen plant Cephalotaxus harringtonia.Omacetaxine mepesuccinate for the treatment of leukemia.Aza-Quaternary Scaffolds from Selective Bond Cleavage of Bridgehead-Substituted 7-Azabicyclo[2.2.1]heptane: Total Synthesis of (+)-Cylindricines C-E and (-)-Lepadiformine A.Rhodium(III)-catalyzed [3+2] annulation of 5-aryl-2,3-dihydro-1H-pyrroles with internal alkynes through C(sp²)-H/alkene functionalization.

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P2860

Homoharringtonine: history, current research, and future direction.

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2001 nî lūn-bûn

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2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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Homoharringtonine: history, current research, and future direction.

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Homoharringtonine: history, current research, and future direction.

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Homoharringtonine: history, current research, and future direction.

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Homoharringtonine: history, current research, and future direction.

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Cheson B

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Kantarjian HM

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Murgo A

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Inhibition of translation in eukaryotic systems by harringtonine

Phase II study of low-dose continuous infusion homoharringtonine in refractory acute myelogenous leukemia.

Sequential emergence of MRP- and MDR1-gene over-expression as well as MDR1-gene translocation in homoharringtonine-selected K562 human leukemia cell lines.

Cephalotaxine esters: antileukemic advance or therapeutic failure?

Homoharringtonine--perspectives on an active new natural product.

Cytotoxicity and cell cycle specificity of homoharringtonine.

Modulation of drug resistance in homoharringtonine-resistant C-1300 neuroblastoma cells with cyclosporine A and dipyridamole.

Effect of homoharringtonine on the viability of murine leukemia P388 cells resistant to either adriamycin, vincristine, or 1-beta-D-arabinofuranosylcytosine.

Phase II study of homoharringtonine in patients with recurrent primary malignant central nervous system tumors.

Evaluation of homoharringtonine efficacy in the treatment of squamous cell carcinoma of the head and neck: a phase II Illinois Cancer Council Study.

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