DEF-1/ASAP1 is a GTPase-activating protein (GAP) for ARF1 that enhances cell motility through a GAP-dependent mechanism. - Wikidata - wikimedia - TriplyDB

DEF-1/ASAP1 is a GTPase-activating protein (GAP) for ARF1 that enhances cell motility through a GAP-dependent mechanism.

DEF-1/ASAP1 is a GTPase-activating protein (GAP) for ARF1 that enhances cell motility through a GAP-dependent mechanism.

http://www.wikidata.org/entity/Q34107593

about

The brefeldin A-inhibited guanine nucleotide-exchange protein, BIG2, regulates the constitutive release of TNFR1 exosome-like vesicles ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome Concerted regulation of cell dynamics by BNIP-2 and Cdc42GAP homology/Sec14p-like, proline-rich, and GTPase-activating protein domains of a novel Rho GTPase-activating protein, BPGAP1 Microvesicle removal of anticancer drugs contributes to drug resistance in human pancreatic cancer cells ACAP-A/B are ArfGAP homologs in dictyostelium involved in sporulation but not in chemotaxis Src-dependent phosphorylation of ASAP1 regulates podosomes.The Arf GAP Asap promotes Arf1 function at the Golgi for cleavage furrow biosynthesis in Drosophila ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.CrkL directs ASAP1 to peripheral focal adhesions.Arf6 plays an early role in platelet activation by collagen and convulxin Substrate specificities and activities of AZAP family Arf GAPs in vivo.The membrane-associated protein, supervillin, accelerates F-actin-dependent rapid integrin recycling and cell motility.AlFx affects the formation of focal complexes by stabilizing the Arf-GAP ASAP1 in a complex with Arf1.Small G proteins in peroxisome biogenesis: the potential involvement of ADP-ribosylation factor 6.A novel mode of action of an ArfGAP, AMAP2/PAG3/Papa lpha, in Arf6 function.Constitutive p21-activated kinase (PAK) activation in breast cancer cells as a result of mislocalization of PAK to focal adhesions GB virus type C E2 protein inhibits human immunodeficiency virus type 1 Gag assembly by downregulating human ADP-ribosylation factor 1.An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I.Ena/VASP is required for endothelial barrier function in vivo.Arf GAPs and their interacting proteins.Arf GAPs as regulators of the actin cytoskeleton.The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis.Overexpression of ASAP1 is associated with poor prognosis in epithelial ovarian cancer.eIF5B increases ASAP1 expression to promote HCC proliferation and invasion.The biology of uveal melanoma The GTPase function of LRRK2.Arf proteins in cancer cell migration.The small GTPase Arf6 is essential for the Tram/Trif pathway in TLR4 signaling.Focus on cutaneous and uveal melanoma specificities.ARFGAP3, an androgen target gene, promotes prostate cancer cell proliferation and migration.Internalization of coxsackievirus A9 is mediated by {beta}2-microglobulin, dynamin, and Arf6 but not by caveolin-1 or clathrin.AMAP1 as a negative-feedback regulator of nuclear factor-κB under inflammatory conditions ASAP3 expression in non-small cell lung cancer: association with cancer development and patients' clinical outcome.OsAGAP, an ARF-GAP from rice, regulates root development mediated by auxin in Arabidopsis.Genome-wide siRNA screen identifies UNC50 as a regulator of Shiga toxin 2 trafficking.CCL18-dependent translocation of AMAP1 is critical for epithelial to mesenchymal transition in breast cancer.Neurotrophin responsiveness of sympathetic neurons is regulated by rapid mobilization of the p75 receptor to the cell surface through TrkA activation of Arf6.

P2860

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P2860

DEF-1/ASAP1 is a GTPase-activating protein (GAP) for ARF1 that enhances cell motility through a GAP-dependent mechanism.

http://www.wikidata.org/entity/Q34107593

description

2001 nî lūn-bûn

@nan

2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

DEF-1/ASAP1 is a GTPase-activa ...... ugh a GAP-dependent mechanism.

@ast

DEF-1/ASAP1 is a GTPase-activa ...... ugh a GAP-dependent mechanism.

@en

DEF-1/ASAP1 is a GTPase-activating protein

@nl

type

label

DEF-1/ASAP1 is a GTPase-activa ...... ugh a GAP-dependent mechanism.

@ast

DEF-1/ASAP1 is a GTPase-activa ...... ugh a GAP-dependent mechanism.

@en

DEF-1/ASAP1 is a GTPase-activating protein

@nl

prefLabel

DEF-1/ASAP1 is a GTPase-activa ...... ugh a GAP-dependent mechanism.

@ast

DEF-1/ASAP1 is a GTPase-activa ...... ugh a GAP-dependent mechanism.

@en

DEF-1/ASAP1 is a GTPase-activating protein

@nl

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P1433

Journal of Biological Chemistry

P1476

DEF-1/ASAP1 is a GTPase-activa ...... ugh a GAP-dependent mechanism.

@en

P2093

Bruce R Zetter

http://www.w3.org/2001/XMLSchema#string

Craig Furman

http://www.w3.org/2001/XMLSchema#string

Sarah M Short

http://www.w3.org/2001/XMLSchema#string

Thomas M Roberts

http://www.w3.org/2001/XMLSchema#string

P2860

ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.

A new paxillin-binding protein, PAG3/Papalpha/KIAA0400, bearing an ADP-ribosylation factor GTPase-activating protein activity, is involved in paxillin recruitment to focal adhesions and cell migration

Identification of a new Pyk2 target protein with Arf-GAP activity

ACAPs are arf6 GTPase-activating proteins that function in the cell periphery

Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein beta

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

High-efficiency transformation of mammalian cells by plasmid DNA

Rho GTPases and the actin cytoskeleton

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

Mechanisms of intracellular protein transport

P304

7962-7969

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scholarly article

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10.1074/JBC.M109149200

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P433

10

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P478

277

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Romesh Subramanian

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2001-12-31T00:00:00Z

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P5875

11584984

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P698

11773070

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