Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice. - Wikidata - wikimedia - TriplyDB

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

http://www.wikidata.org/entity/Q34107651

about

Molecular basis of signaling specificity of insulin and IGF receptors: neglected corners and recent advances Identification of IGF1, SLC4A4, WWOX, and SFMBT1 as hypertension susceptibility genes in Han Chinese with a genome-wide gene-based association study Interaction with Grb14 results in site-specific regulation of tyrosine phosphorylation of the insulin receptor Phosphorylation of Grb14 BPS domain by GSK-3 correlates with complex forming of Grb14 and insulin receptor Polymorphism in the CETP gene region, HDL cholesterol, and risk of future myocardial infarction: Genomewide analysis among 18 245 initially healthy women from the Women's Genome Health Study The role of small adaptor proteins in the control of oncogenic signalingr driven by tyrosine kinases in human cancer Insights into the Genetic Susceptibility to Type 2 Diabetes from Genome-Wide Association Studies of Obesity-Related Traits Insulin receptor signaling in normal and insulin-resistant states Regulation of insulin and type 1 insulin-like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteins An actin filament population defined by the tropomyosin Tpm3.1 regulates glucose uptake Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14 Structural Basis for the Interaction between the Growth Factor-binding Protein GRB10 and the E3 Ubiquitin Ligase NEDD4 Structural Basis for the Interaction of the Adaptor Protein Grb14 with Activated Ras Genetic insights into the mechanisms of Fgf signaling G-protein-coupled receptor rhodopsin regulates the phosphorylation of retinal insulin receptor Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver Tankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and capping The transcriptome of the bowhead whale Balaena mysticetus reveals adaptations of the longest-lived mammal Structural basis for inhibition of the insulin receptor by the adaptor protein Grb14 Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity.Molecular mechanistic associations of human diseases Re-sequencing data for refining candidate genes and polymorphisms in QTL regions affecting adiposity in chicken.Molecular determinants of Grb14-mediated inhibition of insulin signaling.Beta-arrestin inhibits CAMKKbeta-dependent AMPK activation downstream of protease-activated-receptor-2.Pleiotropic genes for metabolic syndrome and inflammation Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution The adaptor protein Grb14 regulates the localization of 3-phosphoinositide-dependent kinase-1.Fine mapping and candidate gene search of quantitative trait loci for growth and obesity using mouse intersubspecific subcongenic intercrosses and exome sequencing.GRB14, GPD1, and GDF8 as potential network collaborators in weight loss-induced improvements in insulin action in human skeletal muscle.Protein kinase Cε modulates insulin receptor localization and trafficking in mouse embryonic fibroblasts.The cell migration protein Grb7 associates with transcriptional regulator FHL2 in a Grb7 phosphorylation-dependent manner.PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle.Phosphorylated Grb14 is an endogenous inhibitor of retinal protein tyrosine phosphatase 1B, and light-dependent activation of Src phosphorylates Grb14.Monoallelic loss of the imprinted gene Grb10 promotes tumor formation in irradiated Nf1+/- mice.Mice with a disruption of the imprinted Grb10 gene exhibit altered body composition, glucose homeostasis, and insulin signaling during postnatal life.Mechanisms regulating GLUT4 glucose transporter expression and glucose transport in skeletal muscle.Grb10 and Grb14: enigmatic regulators of insulin action--and more?Sex differences in human adipose tissues - the biology of pear shape Peripheral disruption of the Grb10 gene enhances insulin signaling and sensitivity in vivo.Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy.

P2860

Q21131281-2E97AFB8-F75A-447D-BC23-5D7E7D3C3701 Q21134736-68338D5C-A030-4E05-A261-8279632C7AD9 Q24313156-292D179D-FD1B-40DD-B25F-53A0A617F3DA Q24337487-F186AEE4-597A-4ADB-9620-9D780E439C31 Q24649155-BBE25967-8357-4C92-B087-A0335504630E Q26770682-E8A2FFE0-B363-49D4-8821-4EC39AAC0B90 Q26781353-43E60BDA-62E2-4F97-82AC-2333B3932598 Q26823171-94ED90A6-919C-4C2A-8C1A-865B2546666C Q26849720-13DAD359-E5D9-49DE-AB50-6AB0D2A3B14D Q27346602-416CFE16-DED4-40E2-B9F6-F6E88DE14D4B Q27656836-44080250-E179-4A26-8FB2-C3284DF47277 Q27665387-9498DED2-F6CD-4BA3-9E07-F89ABBBA9B9C Q27679785-11A47F35-5998-4304-9D24-757B9F247431 Q28066570-66C39796-D53A-42C5-9DD6-B2771E80CF09 Q28507840-FE9679FF-C02C-4517-AB09-CEB86130E49B Q28582739-2BCB3D10-974C-4FD8-9F02-829A9682E853 Q28593281-F9F9E719-EE22-4266-A3F8-0C27CF828DF3 Q28651042-1E9749EE-DD1D-4C6F-9271-E4413DEAEA58 Q28910355-8D07EB02-8152-4971-B516-925A61987AC8 Q30433606-BC521768-2445-429A-BF41-D99E9107D898 Q30496754-BA20139C-86B8-4E14-B2E5-0652B63C5EFA Q30863514-57E18B2C-CF9C-453C-A1C6-A07F218DBA64 Q33642170-C9FCA0D7-CFED-4AF7-9928-E284E598E8C9 Q33698673-379F3E43-BFC4-4E40-B8B2-30123131D9F0 Q34005816-94701FC3-4C48-4A89-B113-529508F29F98 Q34142739-0169AEB4-8ADB-4611-842D-7864CA0367BD Q34328370-9D3AA883-ED2A-43E1-B666-2FF847FA4836 Q34514766-9A536117-D068-4AC1-ACD3-2E45A042C8CD Q34548857-4667818D-EFB2-4D92-8F4E-4622B6FDA436 Q34613391-4B9CA2B3-D582-483A-9488-4C8E7EAB04AC Q34692283-9E913A60-23AB-47C0-8D56-33B32BE7E442 Q35005682-2D3149DD-9EC9-4A2A-BDAA-84155B0A9F39 Q35273915-75BED7FC-D0F6-4B9F-879E-1240DBB41F50 Q35639252-3BC7D8B3-7390-4349-8EA2-DBDD9480EB67 Q35950176-06D06C21-8780-445B-AD4A-0B4191E867F6 Q36011819-264D4DAF-F471-4373-87AC-D068D2DB765D Q36131371-D9C94C83-7196-4A31-B67C-5874F0985586 Q36138909-CAD83828-1900-48E1-8060-CDB2EB7CFAB4 Q36177520-2D028690-EFA1-4083-93C9-C214E7079281 Q36249775-D9684709-3308-484D-8C9F-47005B528AC5

P2860

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

http://www.wikidata.org/entity/Q34107651

description

2004 nî lūn-bûn

@nan

2004 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2004年の論文

@ja

2004年論文

@yue

2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

@ast

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

@en

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

@nl

type

label

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

@ast

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

@en

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

@nl

prefLabel

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

@ast

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

@en

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

@nl

P1433

Q34107651-0ED22DC9-40DD-46B8-BE87-5A69A28FAE06

P1476

Q34107651-256ABFB6-8C0D-4EDE-ABF5-E805E92AFCBA

P2093

Q34107651-0602192F-2761-423C-8ED7-214D28ECF558

Q34107651-124902DF-8297-4EA8-94B7-9B1397F1E341

Q34107651-1B1F74D3-728D-4797-9FFF-FC00C0E45275

Q34107651-30E2950B-3F13-4282-B8EA-64C31EE406C6

Q34107651-741B264B-B4DD-485D-B9F1-F422729C03D1

Q34107651-75C8A630-095A-402A-B277-B619A9E18B6E

Q34107651-B14C8237-73EE-4B60-9810-612F519678B5

Q34107651-B37C260B-69C5-4F71-8172-48C98DC2E8BD

Q34107651-CD51F42E-535F-440F-8041-FA96C0F6FE46

P2860

Q34107651-0C72A3E0-687F-470D-853C-69ED5AFFD1AD

Q34107651-17ECB583-226F-45E1-A635-F63B0AA86194

Q34107651-1B6073E9-C6CC-40C2-84D6-46269955F2FD

Q34107651-1D756FF7-E586-4A91-B3F4-16BF60958D9C

Q34107651-20815829-BCE1-4681-B5BA-D3EF479955AB

Q34107651-226047BE-ACA1-4FE7-A132-D30A3B81794A

Q34107651-234D9A48-A17C-4526-B9D2-6AB03A7D6D53

Q34107651-32C3E95D-BBAE-45F0-BDD4-75D5910F9D95

Q34107651-3B566BC8-0778-4BFC-86CF-98EE122DF590

Q34107651-4685369A-E7FB-471C-BF5A-BF2A7EECFB19

P304

Q34107651-43A7C080-0BC5-48B6-8FBF-50EBDD5E0073

P31

Q34107651-D4BA8E87-2FDA-42E6-8B8B-633FD860B8B0

P356

Q34107651-3937362D-CE1E-40A3-9201-ED1DDF9995A5

P407

Q34107651-B87E4AB2-7A63-44E2-9874-B26B812F9807

P433

Q34107651-D14A513B-4D36-4C10-9F02-5EB0D1795A90

P478

Q34107651-0D4F3F37-1112-425E-81C7-F63D821306FE

P50

Q34107651-AF0410B7-12E9-426A-A51D-03598A25402E

P577

Q34107651-12BD494F-157C-4506-8D49-8276CE4E73CF

P5875

Q34107651-0921DCEE-C176-4B28-8447-1BBA10BE03EF

P698

Q34107651-90586FB6-058C-43A9-B84A-5A75483DAE23

P921

Q34107651-D5DFCE47-3D55-48C2-A981-AD74C9728181

P932

Q34107651-53E9063E-2A9E-4101-AFFA-61633BA2061D

P356

SJ.EMBOJ.7600082

P1433

The EMBO Journal

P1476

Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.

@en

P2093

A Jayne Crew

http://www.w3.org/2001/XMLSchema#string

Christopher J Mitchell

http://www.w3.org/2001/XMLSchema#string

Christopher J Ormandy

http://www.w3.org/2001/XMLSchema#string

David E James

http://www.w3.org/2001/XMLSchema#string

Gregory J Cooney

http://www.w3.org/2001/XMLSchema#string

Juan Carlos Molero

http://www.w3.org/2001/XMLSchema#string

Roger J Daly

http://www.w3.org/2001/XMLSchema#string

Ruth J Lyons

http://www.w3.org/2001/XMLSchema#string

Thomas E Jensen

http://www.w3.org/2001/XMLSchema#string

P2860

Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins

Insulin signalling and the regulation of glucose and lipid metabolism

Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP

Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology and SH2

The adapter protein ZIP binds Grb14 and regulates its inhibitory action on insulin signaling by recruiting protein kinase Czeta

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function

Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partner

The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions

SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

P304

582-593

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.EMBOJ.7600082

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

23

http://www.w3.org/2001/XMLSchema#string

P50

P577

2004-01-29T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

8897057

http://www.w3.org/2001/XMLSchema#string

P698

14749734

http://www.w3.org/2001/XMLSchema#string

P921

P932

1271812

http://www.w3.org/2001/XMLSchema#string