Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41. - Wikidata - wikimedia - TriplyDB

Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41.

Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41.

http://www.wikidata.org/entity/Q34109778

about

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation HIV Genome-Wide Protein Associations: a Review of 30 Years of Research Identification of a cluster of HIV-1 controllers infected with low replicating viruses Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration SERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins.Exposing HIV's weaknesses Structure-guided alterations of the gp41-directed HIV-1 broadly neutralizing antibody 2F5 reveal new properties regarding its neutralizing function.Human and murine APOBEC3s restrict replication of koala retrovirus by different mechanisms.Comparative proteomic analysis of HIV-1 particles reveals a role for Ezrin and EHD4 in the Nef-dependent increase of virus infectivity.The frantic play of the concealed HIV envelope cytoplasmic tail.HIV-1 Nef responsiveness is determined by Env variable regions involved in trimer association and correlates with neutralization sensitivity The Nef-like effect of murine leukemia virus glycosylated gag on HIV-1 infectivity is mediated by its cytoplasmic domain and depends on the AP-2 adaptor complex.The activity of Nef on HIV-1 infectivity Effect of HIV-1 Env on SERINC5 Antagonism The host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles.Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5.SERINC as a Restriction Factor to Inhibit Viral Infectivity and the Interaction with HIV.Inhibiting the Ins and Outs of HIV Replication: Cell-Intrinsic Antiretroviral Restrictions at the Plasma Membrane.HIV-1 cell-to-cell transmission and broadly neutralizing antibodies

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Nef decreases HIV-1 sensitivity to neutralizing antibodies that target the membrane-proximal external region of TMgp41.

http://www.wikidata.org/entity/Q34109778

description

2011 nî lūn-bûn

@nan

2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Nef decreases HIV-1 sensitivit ...... mal external region of TMgp41.

@ast

Nef decreases HIV-1 sensitivit ...... mal external region of TMgp41.

@en

Nef decreases HIV-1 sensitivit ...... mal external region of TMgp41.

@nl

type

label

Nef decreases HIV-1 sensitivit ...... mal external region of TMgp41.

@ast

Nef decreases HIV-1 sensitivit ...... mal external region of TMgp41.

@en

Nef decreases HIV-1 sensitivit ...... mal external region of TMgp41.

@nl

prefLabel

Nef decreases HIV-1 sensitivit ...... mal external region of TMgp41.

@ast

Nef decreases HIV-1 sensitivit ...... mal external region of TMgp41.

@en

Nef decreases HIV-1 sensitivit ...... mal external region of TMgp41.

@nl

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JOURNAL.PPAT.1002442

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Nef decreases HIV-1 sensitivit ...... mal external region of TMgp41.

@en

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Heinrich Göttlinger

http://www.w3.org/2001/XMLSchema#string

Jin Yan

http://www.w3.org/2001/XMLSchema#string

Massimo Pizzato

http://www.w3.org/2001/XMLSchema#string

Rachel P J Lai

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of HIV-1 gp41 including both fusion peptide and membrane proximal external regions

Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2

Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1

Proline-rich (PxxP) motifs in HIV-1 Nef bind to SH3 domains of a subset of Src kinases and are required for the enhanced growth of Nef+ viruses but not for down-regulation of CD4

Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain

Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions

The highly conserved C-terminal dileucine motif in the cytosolic domain of the human immunodeficiency virus type 1 envelope glycoprotein is critical for its association with the AP-1 clathrin adaptor [correction of adapter]

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e1002442

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scholarly article

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10.1371/JOURNAL.PPAT.1002442

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12

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7

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Jonathan L. Heeney

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2011-12-15T00:00:00Z

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51920804

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22194689

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3240605

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