Nuclear factor TDP-43 can affect selected microRNA levels.
about
Early presymptomatic cholinergic dysfunction in a murine model of amyotrophic lateral sclerosisThe genetics and neuropathology of frontotemporal lobar degenerationAccumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer diseaseThe extreme N-terminus of TDP-43 mediates the cytoplasmic aggregation of TDP-43 and associated toxicity in vivoThe involvement of microRNAs in neurodegenerative diseasesNeuronal dark matter: the emerging role of microRNAs in neurodegenerationConverging mechanisms in ALS and FTD: disrupted RNA and protein homeostasisHyperphosphorylation as a defense mechanism to reduce TDP-43 aggregationIdentification of neuronal RNA targets of TDP-43-containing ribonucleoprotein complexesTDP-43 is a transcriptional repressor: the testis-specific mouse acrv1 gene is a TDP-43 target in vivo.miRNA malfunction causes spinal motor neuron disease.Non-human primate model of amyotrophic lateral sclerosis with cytoplasmic mislocalization of TDP-43Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 speciesNeuropathology of Amyotrophic Lateral Sclerosis and Its Variants.The Period protein homolog LIN-42 negatively regulates microRNA biogenesis in C. elegans.Resveratrol modulates the levels of microRNAs targeting genes encoding tumor-suppressors and effectors of TGFβ signaling pathway in SW480 cellsmiRNAs at the interface of cellular stress and diseaseThe emerging roles of microRNAs in the pathogenesis of frontotemporal dementia-amyotrophic lateral sclerosis (FTD-ALS) spectrum disordersCharacterization of the distal polyadenylation site of the ß-adducin (Add2) pre-mRNA.Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.Reversible behavioral phenotypes in a conditional mouse model of TDP-43 proteinopathiesAberrant RNA homeostasis in amyotrophic lateral sclerosis: potential for new therapeutic targets?Downregulation of microRNA-9 in iPSC-derived neurons of FTD/ALS patients with TDP-43 mutations.UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination.A network of RNA and protein interactions in Fronto Temporal Dementia.Advances in epigenetics and epigenomics for neurodegenerative diseases.Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration.TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexesMicroRNAs in Neural Stem Cells and NeurogenesisCause or Effect: Misregulation of microRNA Pathways in Neurodegeneration.Comparison of parallel high-throughput RNA sequencing between knockout of TDP-43 and its overexpression reveals primarily nonreciprocal and nonoverlapping gene expression changes in the central nervous system of DrosophilaDysregulated miRNA biogenesis downstream of cellular stress and ALS-causing mutations: a new mechanism for ALS.TDP-43 and FUS en route from the nucleus to the cytoplasm.Lack of miRNA Misregulation at Early Pathological Stages in Drosophila Neurodegenerative Disease Models.Truncation of the TAR DNA-binding protein 43 is not a prerequisite for cytoplasmic relocalization, and is suppressed by caspase inhibition and by introduction of the A90V sequence variantMicroRNA biogenesis: regulating the regulators.Expression of microRNAs in human post-mortem amyotrophic lateral sclerosis spinal cords provides insight into disease mechanismsThe truncated C-terminal RNA recognition motif of TDP-43 protein plays a key role in forming proteinaceous aggregates.Misregulated RNA processing in amyotrophic lateral sclerosis.RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond.
P2860
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P2860
Nuclear factor TDP-43 can affect selected microRNA levels.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Nuclear factor TDP-43 can affect selected microRNA levels.
@ast
Nuclear factor TDP-43 can affect selected microRNA levels.
@en
Nuclear factor TDP-43 can affect selected microRNA levels.
@nl
type
label
Nuclear factor TDP-43 can affect selected microRNA levels.
@ast
Nuclear factor TDP-43 can affect selected microRNA levels.
@en
Nuclear factor TDP-43 can affect selected microRNA levels.
@nl
prefLabel
Nuclear factor TDP-43 can affect selected microRNA levels.
@ast
Nuclear factor TDP-43 can affect selected microRNA levels.
@en
Nuclear factor TDP-43 can affect selected microRNA levels.
@nl
P2093
P50
P1433
P1476
Nuclear factor TDP-43 can affect selected microRNA levels.
@en
P2093
Francisco Baralle
Laura De Conti
Marco Baralle
P304
P356
10.1111/J.1742-4658.2010.07643.X
P407
P577
2010-05-01T00:00:00Z