about
Newer gene editing technologies toward HIV gene therapyGenome-edited human stem cell-derived beta cells: a powerful tool for drilling down on type 2 diabetes GWAS biologyDissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing toolsTherapeutic genome editing: prospects and challengesQuantifying the transcriptional output of single alleles in single living mammalian cells.Zinc finger nuclease mediated knockout of ADP-dependent glucokinase in cancer cell lines: effects on cell survival and mitochondrial oxidative metabolism.Structure based design of protein linkers for zinc finger nuclease.Rescue the failed half-ZFN by a sensitive mammalian cell-based luciferase reporter systemGenomic editing tools to model human diseases with isogenic pluripotent stem cells.Comparison of T7E1 and surveyor mismatch cleavage assays to detect mutations triggered by engineered nucleases.Targeted In Situ Gene Correction of Dysfunctional APOE Alleles to Produce Atheroprotective Plasma ApoE3 Protein.Balancing between affinity and speed in target DNA search by zinc-finger proteins via modulation of dynamic conformational ensemblePluripotent stem cell applications for regenerative medicineEENdb: a database and knowledge base of ZFNs and TALENs for endonuclease engineeringMagnetic separation and antibiotics selection enable enrichment of cells with ZFN/TALEN-induced mutations.Structural basis for specific single-stranded RNA recognition by designer pentatricopeptide repeat proteinsDeimmunization for gene therapy: host matching of synthetic zinc finger constructs enables long-term mutant Huntingtin repression in mice.An alternative novel tool for DNA editing without target sequence limitation: the structure-guided nucleaseThermodynamic Additivity for Impacts of Base-Pair Substitutions on Association of the Egr-1 Zinc-Finger Protein with DNA.Oligonucleotide-directed gene-editing technology: mechanisms and future prospects.Use of genome-editing tools to treat sickle cell disease.May I Cut in? Gene Editing Approaches in Human Induced Pluripotent Stem Cells.Compact designer TALENs for efficient genome engineering.Speed-stability paradox in DNA-scanning by zinc-finger proteins.A Prospective Treatment Option for Lysosomal Storage Diseases: CRISPR/Cas9 Gene Editing Technology for Mutation Correction in Induced Pluripotent Stem Cells.Gene Editing and Human Pluripotent Stem Cells: Tools for Advancing Diabetes Disease Modeling and Beta-Cell Development.Prediction of DNA-binding specificity in zinc finger proteins.Minimum length of direct repeat sequences required for efficient homologous recombination induced by zinc finger nuclease in yeast.Opportunities and challenges for metabolic engineering of secondary metabolite pathways for improved human health characters in fruit and vegetable cropsHigh-throughput ‘On Chip’ Protein and Nucleic Acid Transfection
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Zinc-finger nucleases: how to play two good hands.
@ast
Zinc-finger nucleases: how to play two good hands.
@en
Zinc-finger nucleases: how to play two good hands.
@nl
type
label
Zinc-finger nucleases: how to play two good hands.
@ast
Zinc-finger nucleases: how to play two good hands.
@en
Zinc-finger nucleases: how to play two good hands.
@nl
prefLabel
Zinc-finger nucleases: how to play two good hands.
@ast
Zinc-finger nucleases: how to play two good hands.
@en
Zinc-finger nucleases: how to play two good hands.
@nl
P2860
P356
P1433
P1476
Zinc-finger nucleases: how to play two good hands.
@en
P2093
Mark Isalan
P2860
P2888
P356
10.1038/NMETH.1805
P577
2011-12-28T00:00:00Z
P5875
P6179
1023839866