The PXR is a drug target for chronic inflammatory liver disease. - Wikidata - wikimedia - TriplyDB

The PXR is a drug target for chronic inflammatory liver disease.

The PXR is a drug target for chronic inflammatory liver disease.

http://www.wikidata.org/entity/Q34118368

about

Why we scratch an itch: the molecules, cells and circuits of itch Pregnane X receptor as a target for treatment of inflammatory bowel disorders Targeting xenobiotic receptors PXR and CAR for metabolic diseases Sustained Isoprostane E2 Elevation, Inflammation and Fibrosis after Acute Ischaemia-Reperfusion Injury Are Reduced by Pregnane X Receptor Activation Alleviation of gut inflammation by Cdx2/Pxr pathway in a mouse model of chemical colitis Hepatic effects of tartrazine (E 102) after systemic exposure are independent of oestrogen receptor interactions in the mouse.Sulfotransferase genes: regulation by nuclear receptors in response to xeno/endo-biotics.Targeting the pregnane X receptor in liver injury.Pregnane X receptor modulates the inflammatory response in primary cultures of hepatocytes RNA-Seq reveals common and unique PXR- and CAR-target gene signatures in the mouse liver transcriptome.Nuclear receptors as drug targets in cholestatic liver diseases.Xenobiotic receptor humanized mice and their utility.Nuclear receptors in the cross-talk of drug metabolism and inflammation.PXR cross-talks with internal and external signals in physiological and pathophysiological responses.Bile acid receptors as targets for drug development.The role of bile acids in functional GI disorders.Different dose-dependent mechanisms are involved in early cyclosporine a-induced cholestatic effects in hepaRG cells.Anticholestatic effects of bezafibrate in patients with primary biliary cirrhosis treated with ursodeoxycholic acid.Functions of pregnane X receptor in self-detoxification.From pathogenesis to novel therapies in the treatment of primary biliary cholangitis.Role of pregnane X-receptor in regulating bacterial translocation in chronic liver diseases.Role of Toll-like receptor 4 in drug-drug interaction between paclitaxel and irinotecan in vitro.Identification of a xenobiotic as a potential environmental trigger in primary biliary cholangitis Retinoid X Receptor Antagonists

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P2860

The PXR is a drug target for chronic inflammatory liver disease.

http://www.wikidata.org/entity/Q34118368

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

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2010年论文

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name

The PXR is a drug target for chronic inflammatory liver disease.

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The PXR is a drug target for chronic inflammatory liver disease.

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The PXR is a drug target for chronic inflammatory liver disease.

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type

label

The PXR is a drug target for chronic inflammatory liver disease.

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The PXR is a drug target for chronic inflammatory liver disease.

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The PXR is a drug target for chronic inflammatory liver disease.

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The PXR is a drug target for chronic inflammatory liver disease.

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The PXR is a drug target for chronic inflammatory liver disease.

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The PXR is a drug target for chronic inflammatory liver disease.

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J.JSBMB.2010.04.012

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The Journal of Steroid Biochemistry and Molecular Biology

P1476

The PXR is a drug target for chronic inflammatory liver disease.

@en

P2093

Andrew Axon

http://www.w3.org/2001/XMLSchema#string

David E Cowie

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Derek A Mann

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Dimitrios K Konstantinou

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Harald Carlsen

http://www.w3.org/2001/XMLSchema#string

Karen Wallace

http://www.w3.org/2001/XMLSchema#string

Matthew C Wright

http://www.w3.org/2001/XMLSchema#string

Matthew Koruth

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Stephen J Hill

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Steven A White

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P2860

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

Effects of long-term rifampicin administration in primary biliary cirrhosis

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

Missing pieces in the NF-kappaB puzzle

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

Tumor necrosis factor alpha transcription in macrophages is attenuated by an autocrine factor that preferentially induces NF-kappaB p50.

A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response

Peroxisome proliferator-activated receptors and inflammation.

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137-148

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10.1016/J.JSBMB.2010.04.012

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2-3

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120

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