Environmental DNA-encoded antibiotics fasamycins A and B inhibit FabF in type II fatty acid biosynthesis - Wikidata - wikimedia - TriplyDB

Environmental DNA-encoded antibiotics fasamycins A and B inhibit FabF in type II fatty acid biosynthesis

Environmental DNA-encoded antibiotics fasamycins A and B inhibit FabF in type II fatty acid biosynthesis

http://www.wikidata.org/entity/Q34120353

about

Whole-genome sequencing targets drug-resistant bacterial infections Expanding our understanding of sequence-function relationships of type II polyketide biosynthetic gene clusters: bioinformatics-guided identification of Frankiamicin A from Frankia sp. EAN1pec Designing and Implementing an Assay for the Detection of Rare and Divergent NRPS and PKS Clones in European, Antarctic and Cuban Soils Endless Resistance. Endless Antibiotics?Mining the metabiome: identifying novel natural products from microbial communities.Metagenomic small molecule discovery methods.Functional metagenomic discovery of bacterial effectors in the human microbiome and isolation of commendamide, a GPCR G2A/132 agonist Dung-inhabiting fungi: a potential reservoir of novel secondary metabolites for the control of plant pathogens.Inhibition of the growth of Bacillus subtilis DSM10 by a newly discovered antibacterial protein from the soil metagenome.Environmental fatty acids enable emergence of infectious Staphylococcus aureus resistant to FASII-targeted antimicrobials.Emerging trends in the discovery of natural product antibacterials.Recent advances in inhibitors of bacterial fatty acid synthesis type II (FASII) system enzymes as potential antibacterial agents.Strategies for target identification of antimicrobial natural products.Formicamycins, antibacterial polyketides produced by Streptomyces formicae isolated from African Tetraponera plant-ants.Phylogeny-guided (meta)genome mining approach for the targeted discovery of new microbial natural products.Naphthacemycins, novel circumventors of β-lactam resistance in MRSA, produced by Streptomyces sp. KB-3346-5. I. The taxonomy of the producing strain, and the fermentation, isolation and antibacterial activities.Naphthacemycins, novel circumventors of β-lactam resistance in MRSA, produced by Streptomyces sp. KB-3346-5. II. Structure elucidation.Total synthesis of (±)-naphthacemycin A9, possessing both antibacterial activity against methicillin-resistant Staphylococcus aureus and circumventing effect of β-lactam resistance.Tetarimycin A, an MRSA-active antibiotic identified through induced expression of environmental DNA gene clusters.Advancing Weed Management Strategies Using Metagenomic Techniques Mutation in Elongation Factor G Confers Resistance to the Antibiotic Argyrin in the Opportunistic PathogenPseudomonas aeruginosa Structures of Pseudomonas aeruginosa β-ketoacyl-(acyl-carrier-protein) synthase II (FabF) and a C164Q mutant provide templates for antibacterial drug discovery and identify a buried potassium ion and a ligand-binding site that is an artefact of the Metagenomics: An Application Based Perspective

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P2860

Environmental DNA-encoded antibiotics fasamycins A and B inhibit FabF in type II fatty acid biosynthesis

http://www.wikidata.org/entity/Q34120353

description

2012 nî lūn-bûn

@nan

2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2012年の論文

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2012年論文

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2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

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name

Environmental DNA-encoded anti ...... ype II fatty acid biosynthesis

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Environmental DNA-encoded anti ...... ype II fatty acid biosynthesis

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Environmental DNA-encoded anti ...... ype II fatty acid biosynthesis

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type

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Environmental DNA-encoded anti ...... ype II fatty acid biosynthesis

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Environmental DNA-encoded anti ...... ype II fatty acid biosynthesis

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Environmental DNA-encoded anti ...... ype II fatty acid biosynthesis

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Environmental DNA-encoded anti ...... ype II fatty acid biosynthesis

@ast

Environmental DNA-encoded anti ...... ype II fatty acid biosynthesis

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Environmental DNA-encoded anti ...... ype II fatty acid biosynthesis

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Journal of the American Chemical Society

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Environmental DNA-encoded anti ...... ype II fatty acid biosynthesis

@en

P2093

Boojala Vijay B Reddy

http://www.w3.org/2001/XMLSchema#string

Debjani Chakraborty

http://www.w3.org/2001/XMLSchema#string

Scott B Dewell

http://www.w3.org/2001/XMLSchema#string

Sean F Brady

http://www.w3.org/2001/XMLSchema#string

Zhiyang Feng

http://www.w3.org/2001/XMLSchema#string

P2860

The Uncultured Microbial Majority

Fast and accurate short read alignment with Burrows-Wheeler transform

Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

The Sequence Alignment/Map format and SAMtools

Antibacterial targets in fatty acid biosynthesis

Anthrabenzoxocinones from Streptomyces sp. as liver X receptor ligands and antibacterial agents

Stampy: a statistical algorithm for sensitive and fast mapping of Illumina sequence reads

Determination of selectivity and efficacy of fatty acid synthesis inhibitors.

Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli.

Dindel: accurate indel calls from short-read data.

P304

2981-2987

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scholarly article

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10.1021/JA207662W

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6

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134

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2012-02-02T00:00:00Z

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221728726

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22224500

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3335777

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