about
New agents for the treatment of drug-resistant Mycobacterium tuberculosisA Review on Platensimycin: A Selective FabF InhibitorThe Role of Medical Structural Genomics in Discovering New Drugs for Infectious DiseasesInhibition of the fungal fatty acid synthase type I multienzyme complexNew design platform for malonyl-CoA-acyl carrier protein transacylaseStructure of the Yersinia pestis FabV Enoyl-ACP Reductase and Its Interaction with Two 2-Pyridone InhibitorsAntibiotics May Trigger Mitochondrial Dysfunction Inducing Psychiatric DisordersSlow onset inhibition of bacterial beta-ketoacyl-acyl carrier protein synthases by thiolactomycin.Discovery of a novel and potent class of F. tularensis enoyl-reductase (FabI) inhibitors by molecular shape and electrostatic matchingEnvironmental DNA-encoded antibiotics fasamycins A and B inhibit FabF in type II fatty acid biosynthesisComplexomics study of two Helicobacter pylori strains of two pathological origins: potential targets for vaccine development and new insight in bacteria metabolism.Metabolism-directed structure optimization of benzimidazole-based Francisella tularensis enoyl-reductase (FabI) inhibitors.How bacterial pathogens eat host lipids: implications for the development of fatty acid synthesis therapeutics.The impact of fatty acids on the antibacterial properties of N-thiolated β-lactams.A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy.Virtually Designed Triclosan-Based Inhibitors of Enoyl-Acyl Carrier Protein Reductase of Mycobacterium tuberculosis and of Plasmodium falciparum.Platensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine.Inhibition of Candida parapsilosis fatty acid synthase (Fas2) induces mitochondrial cell death in serumA Genetic Screen Reveals Novel Targets to Render Pseudomonas aeruginosa Sensitive to Lysozyme and Cell Wall-Targeting AntibioticsCrystallographic insights into the structure-activity relationships of diazaborine enoyl-ACP reductase inhibitors.QSAR based therapeutic management of M. tuberculosis.Unsymmetric aryl-alkyl disulfide growth inhibitors of methicillin-resistant Staphylococcus aureus and Bacillus anthracisThiolactomycin-Based Inhibitors of Bacterial β-Ketoacyl-ACP Synthases with in Vivo Activity.Recent advances in the chemistry and biology of naturally occurring antibiotics.Current understanding of fatty acid biosynthesis and the acyl carrier protein.N-acylated derivatives of sulfamethoxazole block Chlamydia fatty acid synthesis and interact with FabF.Enoyl acyl carrier protein reductase inhibitors: a patent review (2006 - 2010).Proteomic signatures in antibiotic research.Biotin biosynthesis in Mycobacterium tuberculosis: physiology, biochemistry and molecular intervention.Structure, function and selective inhibition of bacterial acetyl-coa carboxylase.Inhibitors of fatty acid synthesis in prokaryotes and eukaryotes as anti-infective, anticancer and anti-obesity drugs.The structural role of the carrier protein--active controller or passive carrier.Molecular modeling studies of Fatty acyl-CoA synthetase (FadD13) from Mycobacterium tuberculosis--a potential target for the development of antitubercular drugs.Docking and molecular dynamics studies on triclosan derivatives binding to FabI.Key Structures and Interactions for Binding of Mycobacterium tuberculosis Protein Kinase B Inhibitors from Molecular Dynamics Simulation.Development of a triclosan scaffold which allows for adaptations on both the A- and B-ring for transport peptides.Deletion of fabN in Enterococcus faecalis results in unsaturated fatty acid auxotrophy and decreased release of inflammatory cytokines.Retrieval of Enterobacteriaceae drug targets using singular value decomposition.Short and Efficient Synthesis of Alkyl- and Aryl-Ortho-Hydroxy-Anilides and their Antibiotic Activity.Membrane Affinity of Platensimycin and Its Dialkylamine Analogs.
P2860
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P2860
description
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im August 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: October 2007)
@en
vedecký článok (publikovaný 2007-10)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd in 2007-10)
@nl
наукова стаття, опублікована в жовтні 2007
@uk
مقالة علمية (نشرت في أكتوبر 2007)
@ar
name
Antibacterial targets in fatty acid biosynthesis
@ast
Antibacterial targets in fatty acid biosynthesis
@en
Antibacterial targets in fatty acid biosynthesis
@nl
type
label
Antibacterial targets in fatty acid biosynthesis
@ast
Antibacterial targets in fatty acid biosynthesis
@en
Antibacterial targets in fatty acid biosynthesis
@nl
prefLabel
Antibacterial targets in fatty acid biosynthesis
@ast
Antibacterial targets in fatty acid biosynthesis
@en
Antibacterial targets in fatty acid biosynthesis
@nl
P2860
P1476
Antibacterial targets in fatty acid biosynthesis
@en
P2093
H Tonie Wright
P2860
P304
P356
10.1016/J.MIB.2007.07.001
P407
P577
2007-08-17T00:00:00Z