Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim. - Wikidata - wikimedia - TriplyDB

Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.

Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.

http://www.wikidata.org/entity/Q34124538

about

Regulation of Bim in Health and Disease Questions and controversies: the role of necroptosis in liver disease Molecular mechanisms of liver injury and hepatocarcinogenesis: focusing on the role of stress-activated MAPK Inflammation- and stress-related signaling pathways in hepatocarcinogenesis X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C TNFα induces survival through the FLIP-L-dependent activation of the MAPK/ERK pathway RIP3 mediates the embryonic lethality of caspase-8-deficient mice c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice The liver-specific tumor suppressor STAT5 controls expression of the reactive oxygen species-generating enzyme NOX4 and the proapoptotic proteins PUMA and BIM in mice.Hedgehog inhibition promotes a switch from Type II to Type I cell death receptor signaling in cancer cells Modeling the TNFα-induced apoptosis pathway in hepatocytes.Cyclic AMP-guanine exchange factor activation inhibits JNK-dependent lipopolysaccharide-induced apoptosis in rat hepatocytes.The strength of the Fas ligand signal determines whether hepatocytes act as type 1 or type 2 cells in murine livers.Differential roles of Epac in regulating cell death in neuronal and myocardial cells.Hepatocyte death: a clear and present danger.Cholecystokinin octapeptide antagonizes apoptosis in human retinal pigment epithelial cells The many roles of FAS receptor signaling in the immune system Synergistic induction of cell death in liver tumor cells by TRAIL and chemotherapeutic drugs via the BH3-only proteins Bim and Bid Apoptosis as a mechanism for liver disease progression.Death Receptor-Mediated Cell Death and Proinflammatory Signaling in Nonalcoholic Steatohepatitis.Bid and Bim collaborate during induction of T cell death in persistent infection.Role of TRAIL and the pro-apoptotic Bcl-2 homolog Bim in acetaminophen-induced liver damage.PUMA-mediated apoptosis drives chemical hepatocarcinogenesis in mice.Fas death receptor signalling: roles of Bid and XIAP.Gene Expression Analysis Indicates Divergent Mechanisms in DEN-Induced Carcinogenesis in Wild Type and Bid-Deficient Livers.Lowering blood ammonia prevents hepatocyte injury and apoptosis.Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome The BH3-only protein Bad is dispensable for TNF-mediated cell death.The protective role of the transmembrane thioredoxin-related protein TMX in inflammatory liver injury.The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver.Runx1 is a co-activator with FOXO3 to mediate transforming growth factor beta (TGFbeta)-induced Bim transcription in hepatic cells Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis Apoptosis and necrosis in the liver Mechanisms of liver disease: cross-talk between the NF-kappaB and JNK pathways.X chromosome-linked inhibitor of apoptosis regulates cell death induction by proapoptotic receptor agonists.A20 prevents chronic liver inflammation and cancer by protecting hepatocytes from death.Caspase inhibitors for the treatment of hepatitis C.Deciphering the rules of programmed cell death to improve therapy of cancer and other diseases Rejuvenating Bi(d)ology.

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P2860

Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.

http://www.wikidata.org/entity/Q34124538

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

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name

Fatal hepatitis mediated by tu ...... BH3-only proteins Bid and Bim.

@ast

Fatal hepatitis mediated by tu ...... BH3-only proteins Bid and Bim.

@en

Fatal hepatitis mediated by tu ...... BH3-only proteins Bid and Bim.

@nl

type

label

Fatal hepatitis mediated by tu ...... BH3-only proteins Bid and Bim.

@ast

Fatal hepatitis mediated by tu ...... BH3-only proteins Bid and Bim.

@en

Fatal hepatitis mediated by tu ...... BH3-only proteins Bid and Bim.

@nl

prefLabel

Fatal hepatitis mediated by tu ...... BH3-only proteins Bid and Bim.

@ast

Fatal hepatitis mediated by tu ...... BH3-only proteins Bid and Bim.

@en

Fatal hepatitis mediated by tu ...... BH3-only proteins Bid and Bim.

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P356

J.IMMUNI.2008.10.017

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Fatal hepatitis mediated by tu ...... BH3-only proteins Bid and Bim.

@en

P2093

Erika Cretney

http://www.w3.org/2001/XMLSchema#string

Philipp J Jost

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Raffi Gugasyan

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Steve Gerondakis

http://www.w3.org/2001/XMLSchema#string

Tak W Mak

http://www.w3.org/2001/XMLSchema#string

Vishva M Dixit

http://www.w3.org/2001/XMLSchema#string

P2860

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

Death receptors: signaling and modulation

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56-66

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scholarly article

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10.1016/J.IMMUNI.2008.10.017

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1

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30

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Andreas Strasser

Philippe Bouillet

Thomas Kaufmann

Hamsa Puthalakath

Marc Pellegrini

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2009-01-01T00:00:00Z

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23716212

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19119023

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2938743

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