Camptothecin attenuates cytochrome P450 3A4 induction by blocking the activation of human pregnane X receptor
about
Development of BODIPY FL vindoline as a novel and high-affinity pregnane X receptor fluorescent probe.Pregnane X receptor and drug-induced liver injury.Overcoming drug resistance by regulating nuclear receptors.Small-molecule modulators of the constitutive androstane receptor.Fucoxanthin attenuates rifampin-induced cytochrome P450 3A4 (CYP3A4) and multiple drug resistance 1 (MDR1) gene expression through pregnane X receptor (PXR)-mediated pathways in human hepatoma HepG2 and colon adenocarcinoma LS174T cells.Nuclear receptors in the multidrug resistance through the regulation of drug-metabolizing enzymes and drug transporters.Small-molecule modulators of PXR and CAR.Sesamin: A Naturally Occurring Lignan Inhibits CYP3A4 by Antagonizing the Pregnane X Receptor Activation.Selective Inhibition of Bakuchicin Isolated from Psoralea corylifolia on CYP1A in Human Liver MicrosomesPXR antagonists and implication in drug metabolism.Differential regulation of CYP3A4 promoter activity by a new class of natural product derivatives binding to pregnane X receptor.A vinblastine fluorescent probe for pregnane X receptor in a time-resolved fluorescence resonance energy transfer assay.Pregnane xenobiotic receptor in cancer pathogenesis and therapeutic response.Allyl isothiocyanate (AITC) inhibits pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation and protects against acetaminophen- and amiodarone-induced cytotoxicity.Effect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity.Probing ligand structure-activity relationships in pregnane X receptor (PXR): efavirenz and 8-hydroxyefavirenz exhibit divergence in activation.Determination of CYP3A4 Inducing Properties of Compounds Using a Laboratory-Developed Cell-Based Assay.
P2860
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P2860
Camptothecin attenuates cytochrome P450 3A4 induction by blocking the activation of human pregnane X receptor
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Camptothecin attenuates cytoch ...... n of human pregnane X receptor
@ast
Camptothecin attenuates cytoch ...... n of human pregnane X receptor
@en
Camptothecin attenuates cytoch ...... n of human pregnane X receptor
@nl
type
label
Camptothecin attenuates cytoch ...... n of human pregnane X receptor
@ast
Camptothecin attenuates cytoch ...... n of human pregnane X receptor
@en
Camptothecin attenuates cytoch ...... n of human pregnane X receptor
@nl
prefLabel
Camptothecin attenuates cytoch ...... n of human pregnane X receptor
@ast
Camptothecin attenuates cytoch ...... n of human pregnane X receptor
@en
Camptothecin attenuates cytoch ...... n of human pregnane X receptor
@nl
P2093
P2860
P356
P1476
Camptothecin attenuates cytoch ...... n of human pregnane X receptor
@en
P2093
P2860
P304
P356
10.1124/JPET.110.168294
P407
P577
2010-05-26T00:00:00Z