Prion protein in Alzheimer's pathogenesis: a hot and controversial issue. - Wikidata - wikimedia - TriplyDB

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

http://www.wikidata.org/entity/Q34130611

about

Characterizing affinity epitopes between prion protein and β-amyloid using an epitope mapping immunoassay Amyloid oligomer neurotoxicity, calcium dysregulation, and lipid rafts Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an Alzheimer's disease model mouse The intersection of amyloid beta and tau at synapses in Alzheimer's disease Immunomodulation for prion and prion-related diseases.Amyloid-beta42 interacts mainly with insoluble prion protein in the Alzheimer brain.The sheddase ADAM10 is a potent modulator of prion disease.Soluble Aβ oligomer production and toxicity.α-Secretase-derived fragment of cellular prion, N1, protects against monomeric and oligomeric amyloid β (Aβ)-associated cell death.Soluble prion protein inhibits amyloid-β (Aβ) fibrillization and toxicity.Pathogenic prions deviate PrP(C) signaling in neuronal cells and impair A-beta clearance The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease.Alzheimer's amyloid-β oligomers rescue cellular prion protein induced tau reduction via the Fyn pathway.Allosteric function and dysfunction of the prion protein.Prion protein oligomer and its neurotoxicity.Overcoming barriers and thresholds - signaling of oligomeric Aβ through the prion protein to Fyn.Prions and prion-like pathogens in neurodegenerative disorders.Exosomal cellular prion protein drives fibrillization of amyloid beta and counteracts amyloid beta-mediated neurotoxicity.Role of amyloid β protein receptors in mediating synaptic plasticity.High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer's disease.Nucleic Acid Aptamers: Emerging Applications in Medical Imaging, Nanotechnology, Neurosciences, and Drug Delivery.PDK1 decreases TACE-mediated α-secretase activity and promotes disease progression in prion and Alzheimer's diseases.Intraneuronally injected amyloid β inhibits long-term potentiation in rat hippocampal slices.Increased prion protein processing and expression of metabotropic glutamate receptor 1 in a mouse model of Alzheimer's disease.[From prion diseases to Alzheimer's disease: a common therapeutic target, PDK1].The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade.

P2860

Q24313479-2F76E1D9-9D6C-4BFD-A642-144C7C01A071 Q28742804-C21BFAA3-B989-4845-A307-866E8172031F Q33718694-4A17C537-C646-45FD-A3C5-95E9D56A9B17 Q34054680-CD3C6B27-DEAB-4452-8081-997AD4A433DF Q34565644-7F4AF95D-18FE-4A63-8BD7-E586754DE3AF Q34868772-13A7A522-78F0-4D03-BBCE-9B7FEE7B6F32 Q35137829-85A8BBAC-7FE9-4598-83BD-4EB1FE6E8E52 Q35663419-9E9D5292-CB39-4887-99A9-69E5B42648BC Q35763065-792037C8-C56A-4EA2-95E6-8E49459AC7C0 Q36286065-B43BF45D-72A1-4453-830E-F81FBD7F8862 Q36586500-8A5B1E07-78E9-4F8A-B638-35190A12DC09 Q36600160-37084F78-5371-40A3-BA49-7530DCDFD9FA Q37186173-38A9E67D-BB13-4A0A-A78A-828A44074C2D Q37943799-7D3C83DE-0AF0-43D4-8421-547CC6148061 Q38096098-885BCFF3-F626-40E6-85D9-3880D1F810A4 Q38121684-34114BCE-8C23-4ACB-9702-4175FC021463 Q38273271-3D94DEBC-F35D-4F5F-9753-B3FA26D99971 Q38808517-9D0E55D2-03CD-44E6-B74B-E46CF025FC01 Q39245512-7115788A-AC8C-48F0-A646-A20831113163 Q46216495-CBDD34C7-2DC6-4342-AA5D-F76A0C4A0424 Q47104247-AD523387-D5BA-4A23-A006-721C1910DD0A Q47753241-2D216439-302E-4CA1-AAB3-A99373EC8CA9 Q48658737-8C4EE5CD-9853-4FF1-807E-0BA07FECC655 Q51013962-30358C25-1966-4DF5-BDBD-F548C7FB3647 Q53349598-8FD98D29-E89D-4FCE-ABB9-920ADF67BB98 Q54977832-9DD02BC3-DF64-424A-A395-3C7A714BAE24

P2860

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

http://www.wikidata.org/entity/Q34130611

description

2010 nî lūn-bûn

@nan

2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

@ast

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

@en

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

@nl

type

label

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

@ast

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

@en

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

@nl

prefLabel

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

@ast

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

@en

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

@nl

P1433

Q34130611-01243B5E-876F-4AA5-8853-201702D804B7

P1476

Q34130611-4615B519-06EE-4A65-B45D-3A090B51665E

P2093

Q34130611-469D2261-08D3-450C-8A8D-55FE623645D1

P2860

Q34130611-02E9F9AE-B816-436E-9E50-396667E4F091

Q34130611-0F282A2C-AFCE-4EF5-A79B-9C326A1EE3AD

Q34130611-148C4402-FC91-4C3A-BE5C-BA4C74BD3B48

Q34130611-18CB1E3E-E41A-482B-85B9-6CBC6D491AD8

Q34130611-522E3054-9776-4AEA-83F7-DD61B9F5DA3B

Q34130611-6EC20D01-76C4-4E1E-9D67-F93D2EE470D8

Q34130611-722D06F1-B858-468A-AD6D-8217F9033644

Q34130611-8EA0EBBE-3763-47A0-93A9-DDF9713F3E2B

Q34130611-9BC64E20-1229-4DC5-984F-417328FFABE6

Q34130611-9C00A3E5-D748-4A55-B38C-957365FA3E8C

P304

Q34130611-73BA2514-CC29-4639-8D9A-CD4CC9FA05D0

P31

Q34130611-AB5B2292-11ED-4E7A-831E-3A05ED5AF782

P356

Q34130611-97E81CA4-E2E1-4122-8670-D5F1D00E9CE5

P433

Q34130611-58B70894-5B5A-4E93-B2D9-0FFA93CB9A76

P478

Q34130611-1BDA18C7-DB24-472F-A8E5-B717F28FBBE5

P50

Q34130611-F5891EE5-3DE0-4F14-BBDC-9AAD4EDF7FE9

P577

Q34130611-BB6B1FB7-50AA-499C-A656-CC4952D9D9AE

P5875

Q34130611-D7A18C58-233C-479B-B101-94CE28C5C6BF

P698

Q34130611-AF3922E9-F588-4CAB-99C7-10F609F42FCA

P921

Q34130611-6FD1442A-A456-462B-9F7C-2AC0224F9719

Q34130611-FF5B3B48-B860-4354-A478-9A40D564C248

P932

Q34130611-0248ED9E-2F53-4626-8F2A-C65C10E03CDD

P356

P1433

EMBO Molecular Medicine

P1476

Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.

@en

P2093

Iryna Benilova

http://www.w3.org/2001/XMLSchema#string

P2860

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

Unraveling prion strains with cell biology and organic chemistry

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein.

Memory impairment in transgenic Alzheimer mice requires cellular prion protein.

Protein aggregation diseases: pathogenicity and therapeutic perspectives.

Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process.

Probing the biology of Alzheimer's disease in mice.

Prion protein and Abeta-related synaptic toxicity impairment.

P304

289-290

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1002/EMMM.201000088

http://www.w3.org/2001/XMLSchema#string

P433

8

http://www.w3.org/2001/XMLSchema#string

P478

2

http://www.w3.org/2001/XMLSchema#string

P50

Bart De Strooper

P577

2010-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

45584441

http://www.w3.org/2001/XMLSchema#string

P698

20698011

http://www.w3.org/2001/XMLSchema#string

P921

Alzheimer's disease

Prion protein family

P932

3377329

http://www.w3.org/2001/XMLSchema#string