Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein.
about
Glypican-1 mediates both prion protein lipid raft association and disease isoform formationAmyloid beta precursor protein and prion protein have a conserved interaction affecting cell adhesion and CNS developmentSynthetic amyloid-beta oligomers impair long-term memory independently of cellular prion proteinMolecular cross talk between misfolded proteins in animal models of Alzheimer's and prion diseasesSynaptic Cell Adhesion Molecules in Alzheimer's DiseaseAlzheimer's Disease: Mechanism and Approach to Cell Therapyα-Cleavage of cellular prion proteinHijacking PrP(c)-dependent signal transduction: when prions impair Aβ clearanceInsoluble cellular prion protein and its association with prion and Alzheimer diseasesZebrafish prion protein PrP2 controls collective migration process during lateral line sensory system developmentStem Cell Therapy: A Prospective Treatment for Alzheimer's DiseaseAlzheimer's disease and prion proteinDeficiency of the copper chaperone for superoxide dismutase increases amyloid-β productionThe ubiquitin-proteasome system in spongiform degenerative disordersCell line specific modulation of extracellular aβ42 by Hsp40The in vivo brain interactome of the amyloid precursor proteinFunctions of the cellular prion protein, the end of Moore's law, and Ockham's razor theoryThe prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1Memory impairment in transgenic Alzheimer mice requires cellular prion protein.The polybasic N-terminal region of the prion protein controls the physical properties of both the cellular and fibrillar forms of PrP.Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation.Genetic cross-interaction between APOE and PRNP in sporadic Alzheimer's and Creutzfeldt-Jakob diseases.Docosahexaenoic and eicosapentaenoic acids increase prion formation in neuronal cellsContext dependent neuroprotective properties of prion protein (PrP).Beta-amyloid oligomers and cellular prion protein in Alzheimer's disease.beta-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins.Cellular prion protein mediates the toxicity of beta-amyloid oligomers: implications for Alzheimer disease.The retinoic acid receptor beta (Rarb) region of Mmu14 is associated with prion disease incubation time in mouse.The N-terminus of the prion protein is a toxic effector regulated by the C-terminus.The 37kDa/67kDa laminin receptor acts as a receptor for Aβ42 internalization.Reduced CSF turnover and decreased ventricular Aβ42 levels are relatedAn overview of APP processing enzymes and products.Beta-secretase: structure, function, and evolution.Interaction between human prion protein and amyloid-beta (Abeta) oligomers: role OF N-terminal residues.Prion protein in Alzheimer's pathogenesis: a hot and controversial issue.Cellular prion protein expression is not regulated by the Alzheimer's amyloid precursor protein intracellular domain.Prion protein and Abeta-related synaptic toxicity impairment.Role of alpha7 nicotinic acetylcholine receptor in calcium signaling induced by prion protein interaction with stress-inducible protein 1.Plasma prion protein concentration and progression of Alzheimer disease.
P2860
Q21131569-704BF2AF-5EB3-43E3-91C5-EAA81EA26803Q24305972-7A683E02-C9E1-4753-9F2F-2FB1ADAD1644Q24630045-D1C5053B-C8CF-4F77-BC36-F7AFA899D8FAQ24633202-7EE70DEB-27A2-425C-802B-D227C56C11A9Q26744544-65FCEA0E-2070-42A2-8AA8-3FF62C5A34B9Q26778149-6D213C46-B1B7-4ABC-BD7C-8FFD45FF7D52Q26863324-FB6EDB05-AE89-4062-A633-A579BA20698CQ27009790-37608DFD-AAD7-425F-8CA4-D0DFE636616DQ27012706-5CDAB07E-5D43-4CD2-A178-CED0DA8B9699Q27324321-8A99A25E-4269-4856-A30C-C5DB1E0DADF3Q28069506-47B40DB2-1210-416C-A2B3-40538540C45CQ28250275-AA4E3D49-0F31-4E4B-AAA1-3B00E7078628Q28289956-F3D61D7A-4566-4B26-A86F-FC91ADD41416Q28386906-FE59801F-89F0-4892-B982-185CAB0AE4D5Q28483971-54D04735-8BFF-4C22-912C-7E1AFC1B0F71Q28509371-0672916B-DEC2-4F51-8480-A24A1FCAF2ABQ28597985-5602A0A2-B69B-4841-9417-CC3BAC20307FQ28771518-784FB5DD-555B-44AE-AC55-3182FFDC6796Q28910209-D1F7A4D0-C276-41FA-99A0-98BD43A4620FQ30032301-B7E29638-8E01-4DCA-BABE-12FA73962CF5Q30485085-7BE485F7-EAE2-49CC-A66D-EFFC32BE06D2Q30535426-56B69209-8602-4989-AA67-742763062BB2Q31026808-B68E7587-4DE1-4F0C-8554-7EF3FA9DB663Q33369210-2AD0B3B5-B302-471B-A00C-BAAE65E70309Q33595425-8EA4FB9A-E7A9-4ECD-BA52-07A94C396E5FQ33757721-95A9EE9B-F9E0-497E-B0F9-18D1B9421CC9Q33762857-39281F51-9281-4E9C-AC17-202C06973560Q33768032-2539DDCA-7FD6-4C3F-B692-19F297170BD4Q33769410-F01172B0-C5D6-4CDF-9B9F-2FAFB14B1505Q33793628-32742C66-F39E-4CFA-A343-B01BB3C234CAQ33840258-4B860286-B79E-4077-BF0D-3E23DF4F4354Q33898968-D712985C-8239-494D-A569-9784DCD47694Q33927819-9AEC2424-70A8-4529-AA99-616768019B8DQ34066765-7FE48CA6-D5B8-476B-80A6-593FFE3DAE96Q34074414-9EBC9C98-1935-4D22-9933-7B51F47422EBQ34130611-CDA52EBD-68AD-456D-834D-4F332F955BB9Q34171325-4C37650A-A5E8-4471-B120-3738ADA1AD64Q34233877-3EB17A31-789B-4266-81B9-076D88B75B1AQ34299079-F06E9350-177E-4BE8-93AC-E636256B8ECFQ34307247-F34474FF-4E04-4D1B-95A5-D7347477019A
P2860
Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Cellular prion protein regulat ...... r's amyloid precursor protein.
@ast
Cellular prion protein regulat ...... r's amyloid precursor protein.
@en
Cellular prion protein regulat ...... r's amyloid precursor protein.
@en-gb
type
label
Cellular prion protein regulat ...... r's amyloid precursor protein.
@ast
Cellular prion protein regulat ...... r's amyloid precursor protein.
@en
Cellular prion protein regulat ...... r's amyloid precursor protein.
@en-gb
prefLabel
Cellular prion protein regulat ...... r's amyloid precursor protein.
@ast
Cellular prion protein regulat ...... r's amyloid precursor protein.
@en
Cellular prion protein regulat ...... r's amyloid precursor protein.
@en-gb
P2093
P2860
P50
P921
P3181
P356
P1476
Cellular prion protein regulat ...... r's amyloid precursor protein.
@en
P2093
Anthony J Turner
Christopher B Eckman
Elizabeth A Eckman
Herbert N Baybutt
Ishrut Hussain
Nicole T Watt
P2860
P304
11062-11067
P3181
P356
10.1073/PNAS.0609621104
P407
P577
2007-06-15T00:00:00Z