G-protein stimulatory subunit alpha and Gq/11α G-proteins are both required to maintain quiescent stem-like chondrocytes.
about
Role of G-proteins in the differentiation of epiphyseal chondrocytesRegulation of Long Bone Growth in Vertebrates; It Is Time to Catch UpOriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage.Prostacyclin regulates bone growth via the Epac/Rap1 pathway.Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.Haploinsufficiency for either one of the type-II regulatory subunits of protein kinase A improves the bone phenotype of Prkar1a+/- mice.Celecoxib treatment of fibrous dysplasia (FD) in a human FD cell line and FD-like lesions in mice with protein kinase A (PKA) defects.Targeted Deletion of Autophagy Genes Atg5 or Atg7 in the Chondrocytes Promotes Caspase-Dependent Cell Death and Leads to Mild Growth Retardation.Deletion of Gαq in the telencephalon alters specific neurobehavioral outcomes.Knock-In of the Recurrent R368X Mutation of PRKAR1A that Represses cAMP-Dependent Protein Kinase A Activation: A Model of Type 1 Acrodysostosis.Dephosphorylation of the NPR2 guanylyl cyclase contributes to inhibition of bone growth by fibroblast growth factor.Constitutive stimulatory G protein activity in limb mesenchyme impairs bone growth.Genetic and epigenetic defects at the GNAS locus lead to distinct patterns of skeletal growth but similar early-onset obesity.Activation of mTORC1 in chondrocytes does not affect proliferation or differentiation, but causes the resting zone of the growth plate to become disordered.
P2860
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P2860
G-protein stimulatory subunit alpha and Gq/11α G-proteins are both required to maintain quiescent stem-like chondrocytes.
description
2014 nî lūn-bûn
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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2014年の論文
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2014年論文
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2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
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2014年论文
@wuu
name
G-protein stimulatory subunit ...... escent stem-like chondrocytes.
@ast
G-protein stimulatory subunit ...... escent stem-like chondrocytes.
@en
G-protein stimulatory subunit ...... escent stem-like chondrocytes.
@nl
type
label
G-protein stimulatory subunit ...... escent stem-like chondrocytes.
@ast
G-protein stimulatory subunit ...... escent stem-like chondrocytes.
@en
G-protein stimulatory subunit ...... escent stem-like chondrocytes.
@nl
prefLabel
G-protein stimulatory subunit ...... escent stem-like chondrocytes.
@ast
G-protein stimulatory subunit ...... escent stem-like chondrocytes.
@en
G-protein stimulatory subunit ...... escent stem-like chondrocytes.
@nl
P2093
P2860
P50
P356
P1476
G-protein stimulatory subunit ...... escent stem-like chondrocytes.
@en
P2093
Henry M Kronenberg
Karuna K Vuppalapati
Lee S Weinstein
Takao Hirai
P2860
P2888
P356
10.1038/NCOMMS4673
P407
P577
2014-04-30T00:00:00Z
P5875
P6179
1012586243