Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice.
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BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cellsCritical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway.PPARβ/δ promotes HRAS-induced senescence and tumor suppression by potentiating p-ERK and repressing p-AKT signalingDiabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers.Distinct role of FoxO1 in M-CSF- and GM-CSF-differentiated macrophages contributes LPS-mediated IL-10: implication in hyperglycemia.Transcription factor binding site analysis identifies FOXO transcription factors as regulators of the cutaneous wound healing process.Deletion of PDK1 causes cardiac sodium current reduction in miceSuppression of Foxo1 activity and down-modulation of CD62L (L-selectin) in HIV-1 infected resting CD4 T cells.Unbreak my heart: targeting mitochondrial autophagy in diabetic cardiomyopathyHistone deacetylase inhibitors induce autophagy through FOXO1-dependent pathways.The Colonic Crypt Protects Stem Cells from Microbiota-Derived MetabolitesTargeting FoxO1 with AS1842856 suppresses adipogenesis.FOXO1 inhibits osteoclastogenesis partially by antagnozing MYC.Coupling between Nutrient Availability and Thyroid Hormone ActivationAn Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc AxisCytosolic phospholipase A2α regulates G1 progression through modulating FOXO1 activityActive FOXO1 Is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming.FOXO1 inhibits osteosarcoma oncogenesis via Wnt/β-catenin pathway suppression.Endothelial p110γPI3K Mediates Endothelial Regeneration and Vascular Repair After Inflammatory Vascular InjuryProgesterone receptors induce FOXO1-dependent senescence in ovarian cancer cells.FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype.FoxO1 antagonist suppresses autophagy and lipid droplet growth in adipocytesFoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytesEffect and the probable mechanisms of silibinin in regulating insulin resistance in the liver of rats with non-alcoholic fatty liver.Advanced glycosylation end product promotes forkhead box O1 and inhibits Wnt pathway to suppress capacities of epidermal stem cells.Forkhead Protein FoxO1 Acts as a Repressor to Inhibit Cell Differentiation in Human Fetal Pancreatic Progenitor CellsGut-liver interaction in triglyceride-rich lipoprotein metabolism.Targeting hepatic glucose metabolism in the treatment of type 2 diabetes.PDK1 controls upstream PI3K expression and PIP3 generation.Identification of direct forkhead box O1 targets involved in palmitate-induced apoptosis in clonal insulin-secreting cells using chromatin immunoprecipitation coupled to DNA selection and ligation.AKT isoforms modulate Th1-like Treg generation and function in human autoimmune diseaseThe constitutive androstane receptor activator 4-[(4R,6R)-4,6-diphenyl-1,3-dioxan-2-yl]-N,N-dimethylaniline inhibits the gluconeogenic genes PEPCK and G6Pase through the suppression of HNF4α and FOXO1 transcriptional activity.Dormant Pluripotent Cells Emerge during Neural Differentiation of Embryonic Stem Cells in a FoxO3-Dependent Manner.Revealing the potency of Annona muricata leaves extract as FOXO1 inhibitor for diabetes mellitus treatment through computational study.Hypoglycemic effect of lipoic Acid, carnitine and nigella sativa in diabetic rat model.Pancreatic islet regeneration through PDX-1/Notch-1/Ngn3 signaling after gastric bypass surgery in db/db mice.FoxO proteins or loss of functional p53 maintain stemness of glioblastoma stem cells and survival after ionizing radiation plus PI3K/mTOR inhibition.Macrophage CGI-58 deficiency promotes IL-1β transcription by activating the SOCS3-FOXO1 pathway.Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension.Metabolic reprogramming of human CD8+ memory T cells through loss of SIRT1.
P2860
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P2860
Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice.
description
2010 nî lūn-bûn
@nan
2010 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Discovery of novel forkhead bo ...... ycemia in diabetic db/db mice.
@ast
Discovery of novel forkhead bo ...... ycemia in diabetic db/db mice.
@en
Discovery of novel forkhead bo ...... ycemia in diabetic db/db mice.
@nl
type
label
Discovery of novel forkhead bo ...... ycemia in diabetic db/db mice.
@ast
Discovery of novel forkhead bo ...... ycemia in diabetic db/db mice.
@en
Discovery of novel forkhead bo ...... ycemia in diabetic db/db mice.
@nl
prefLabel
Discovery of novel forkhead bo ...... ycemia in diabetic db/db mice.
@ast
Discovery of novel forkhead bo ...... ycemia in diabetic db/db mice.
@en
Discovery of novel forkhead bo ...... ycemia in diabetic db/db mice.
@nl
P2093
P356
P1476
Discovery of novel forkhead bo ...... ycemia in diabetic db/db mice.
@en
P2093
Akiyoshi Shimaya
Hirotsugu Tanaka
Masayuki Shibasaki
Nobuharu Shigematsu
Riyo Maruki
Takeyuki Nagashima
Teruhiko Shimokawa
Yasuharu Urano
P304
P356
10.1124/MOL.110.065714
P577
2010-08-24T00:00:00Z