Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers. - Wikidata - wikimedia - TriplyDB

Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers.

Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers.

http://www.wikidata.org/entity/Q34403048

about

Decellularized scaffolds in regenerative medicine β-Cell regeneration through the transdifferentiation of pancreatic cells: Pancreatic progenitor cells in the pancreas "Inflammaging" as a Druggable Target: A Senescence-Associated Secretory Phenotype-Centered View of Type 2 Diabetes Changes in Regenerative Capacity through Lifespan Stereological analyses of the whole human pancreas.Dedifferentiation, Transdifferentiation, and Proliferation: Mechanisms Underlying Cardiac Muscle Regeneration in Zebrafish Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity β-Cell Replacement Strategies: The Increasing Need for a "β-Cell Dogma".The novel tool of cell reprogramming for applications in molecular medicine.Adult cell plasticity in vivo: de-differentiation and transdifferentiation are back in style.Targeting GLP-1 receptors for repeated magnetic resonance imaging differentiates graded losses of pancreatic beta cells in mice.A systems view of epigenetic networks regulating pancreas development and β-cell function Glucagon is essential for alpha cell transdifferentiation and beta cell neogenesis.Overcoming Insulin Insufficiency by Forced Follistatin Expression in β-cells of db/db Mice.Q&A: insulin secretion and type 2 diabetes: why do β-cells fail?Beta-cell regeneration from vimentin+/MafB+ cells after STZ-induced extreme beta-cell ablation.Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cells Centroacinar Cells Are Progenitors That Contribute to Endocrine Pancreas Regeneration.A Transcriptome-Led Exploration of Molecular Mechanisms Regulating Somatostatin-Producing D-Cells in the Gastric Epithelium.The Soybean Peptide Vglycin Preserves the Diabetic β-cells through Improvement of Proliferation and Inhibition of Apoptosis.Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing β-cells to a δ-like fate and reveals a facultative proliferative capacity in aged β-cells.Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes.REST represses a subset of the pancreatic endocrine differentiation program.Hyperglycaemia attenuates in vivo reprogramming of pancreatic exocrine cells to beta cells in mice.Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types Direct Reprogramming for Pancreatic Beta-Cells Using Key Developmental Genes Use of the Fluidigm C1 platform for RNA sequencing of single mouse pancreatic islet cells.Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist.Type 1 Diabetes--Reaping the Rewards of a Targeted Research Investment.Autonomous interconversion between adult pancreatic α-cells and β-cells after differential metabolic challenges.Beneficial effects of previous exercise training on renal changes in streptozotocin-induced diabetic female rats.IGFBP1 increases β-cell regeneration by promoting α- to β-cell transdifferentiation.PAX6 maintains β cell identity by repressing genes of alternative islet cell types.PAR2 regulates regeneration, transdifferentiation, and death Stepwise reprogramming of liver cells to a pancreas progenitor state by the transcriptional regulator Tgif2.Metabolic Stress and Compromised Identity of Pancreatic Beta Cells.Evidence for Loss in Identity, De-Differentiation, and Trans-Differentiation of Islet β-Cells in Type 2 Diabetes.Diabetes mellitus--advances and challenges in human β-cell proliferation.In vivo reprogramming for tissue repair.Role of transcription factors in the transdifferentiation of pancreatic islet cells.

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Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers.

http://www.wikidata.org/entity/Q34403048

description

2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Diabetes recovery by age-depen ...... -cells into insulin producers.

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Diabetes recovery by age-depen ...... -cells into insulin producers.

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Diabetes recovery by age-depen ...... -cells into insulin producers.

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Diabetes recovery by age-depen ...... δ-cells into insulin producers

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Delphine Baronnier

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Fabrizio Thorel

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Guoqiang Gu

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Jan N Jensen

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Valentina Cigliola

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P2860

Marked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors

Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

Id and development

Id family of helix-loop-helix proteins in cancer

Epigenomic plasticity enables human pancreatic α to β cell reprogramming.

Immunological mechanisms associated with long-term remission of human type 1 diabetes.

Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice.

Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice

Relationship between beta-cell mass and diabetes onset.

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503-507

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10.1038/NATURE13633

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7523

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514

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Fiona M Gribble

Kenichiro Furuyama

Pedro Luis Herrera

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2014-08-20T00:00:00Z

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264904453

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